| Literature DB >> 26001659 |
Eunkyung Cho1, Dong Jin Chung2, Dong Myung Yeo3, Dongwan Sohn4, Yohan Son5, Taejung Kim6, Sung-Tae Hahn7.
Abstract
To determine cut-off value of dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) parameters for differentiation of prostate malignant from benign and cancer with high-grade Gleason score (GS) (GS>7) from low-grade GS (GS≤7), 35 patients (24 malignant and 11 benign) who underwent DCE-MRI were included. Difference between malignant and benign was statistically significant for all magnetic resonance parameters except Ve. The cut-off values were K(trans)=0.184min(-1), Kep=0.695min(-1), iAUC=4.219mmol/l/min, and ADC=1340.5mm(2)/s. A significant difference in mean values of K(trans) and Kep between cancer with high-grade GS and low-grade GS was also observed. K(trans) and Kep showed a significant correlation with GS.Entities:
Keywords: Cut-off value; DCE-MRI; Gleason’s score; Perfusion parameter; Prostate cancer
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Year: 2015 PMID: 26001659 DOI: 10.1016/j.clinimag.2015.04.020
Source DB: PubMed Journal: Clin Imaging ISSN: 0899-7071 Impact factor: 1.605