| Literature DB >> 25992298 |
Jin-Young Min1, Jae Bum Park2, Kyung-Jong Lee2, Kyoung-Bok Min3.
Abstract
OBJECTIVE: This study investigated the impact of occupation on cognitive and physical function within an occupational window of the past 15 years using a nationally representative sample in Korea.Entities:
Year: 2015 PMID: 25992298 PMCID: PMC4436874 DOI: 10.1186/s40557-015-0057-0
Source DB: PubMed Journal: Ann Occup Environ Med ISSN: 2052-4374
Distribution of variables of interest and cognitive and physical function by sex
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| Marital status | |||||
| Married | 1752 | (91.2) | 1354 | (54.5) | |
| Divorced | 32 | (1.7) | 38 | (1.5) | |
| Widowed | 133 | (6.9) | 1086 | (43.7) | |
| Others | 5 | (0.3) | 7 | (0.3) | |
| Educational level | |||||
| No education | 267 | (13.9) | 1070 | (43.0) | |
| Elementary | 618 | (32.2) | 953 | (38.3) | |
| Middle school | 341 | (17.7) | 262 | (10.5) | |
| High school | 446 | (23.2) | 161 | (6.5) | |
| College or more | 249 | (13.0) | 40 | (1.6) | |
| Household income* | |||||
| 1st quartile | 496 | (25.8) | 844 | (34.0) | |
| 2nd quartile | 636 | (33.1) | 781 | (31.4) | |
| 3rd quartile | 495 | (25.8) | 532 | (21.4) | |
| 4th quartile | 295 | (15.3) | 329 | (13.2) | |
| Current employment status | |||||
| Employed | 690 | (35.9) | 336 | (13.5) | |
| Retired | 785 | (40.8) | 453 | (18.2) | |
| Unemployed | 447 | (23.3) | 1697 | (68.3) | |
| Principal job type during lifetime | |||||
| Non-manual work | 468 | (24.3) | 135 | (5.4) | |
| Manual work | 1212 | (63.1) | 1653 | (66.5) | |
| Other | 246 | (12.8) | 699 | (28.1) | |
| Smoking | |||||
| Current smoker | 638 | (33.2) | 91 | (3.7) | |
| Past smoker | 494 | (25.7) | 20 | (0.8) | |
| Nonsmoker | 790 | (41.1) | 2375 | (95.5) | |
| Drinking | |||||
| Yes | 1059 | (55.1) | 277 | (11.1) | |
| No | 863 | (44.9) | 2209 | (88.9) | |
| Chronic disease | |||||
| Hypertension | 627 | (32.6) | 993 | (39.9) | |
| Diabetes mellitus | 295 | (15.3) | 400 | (16.1) | |
| Cardiac disorder | 122 | (6.3) | 187 | (7.5) | |
| Cerebral vascular disease | 115 | (6.0) | 87 | (3.5) | |
| BMI¶ | |||||
| Severe obesity | 22 | (1.1) | 67 | (2.7) | |
| Obesity | 321 | (16.7) | 499 | (20.1) | |
| Overweight | 550 | (28.6) | 602 | (24.2) | |
| Normal | 881 | (45.8) | 1040 | (41.8) | |
| Underweight | 111 | (5.8) | 150 | (6.0) | |
| MMSE | |||||
| ≤17 | 176 | (9.2) | 593 | (23.9) | |
| >17 | 1746 | (90.8) | 1893 | (76.1) | |
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| 24.33 | (5.80) | 21.12 | (6.83) | |
| IADL | |||||
| ≤7 | 1846 | (96.0) | 2385 | (95.9) | |
| >7 | 76 | (4.0) | 101 | (4.1) | |
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| 0.78 | (2.11) | 0.81 | (2.14) | |
| ADL | |||||
| <1 | 1804 | (93.9) | 2307 | (92.8) | |
| ≥1 | 118 | (6.1) | 179 | (7.2) | |
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| 0.26 | (1.18) | 0.23 | (1.01) | |
*Household income: 1st quartile, below 3 million won; 2nd quartile, between 3 million and 12 million won; 3rd quartile, between 12 million and 30 million won; 4th quartile, more than 30 million won.
¶BMI(body mass index): severe obesity, BMI ≥30; obesity, 30 < BMI ≤ 25; overweight, 25 < BMI ≤ 23; normal,23 < BMI ≤ 18.5; underweight, BMI < 18.5.
Logistic analysis of work duration and functional status by sex
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| MMSE | |||||||
| 15 | 0.532 | 0.320 | 0.429 | 1.598 | 0.988 | 0.934 | |
| (0.326,0.869) | (0.190,0.538) | (0.243,0.759) | (1.205,2.118) | (0.730,1.336) | (0.677,1.288) | ||
| 8-14 | 0.658 | 0.469 | 0.533 | 1.512 | 1.048 | 1.037 | |
| (0.400,1.083) | (0.277,0.793) | (0.300,0.946) | (1.122,2.038) | (0.760,1.445) | (0.739,1.455) | ||
| 1-7 | 0.507 | 0.452 | 0.425 | 1.165 | 0.904 | 0.854 | |
| (0.299,0.862) | (0.259,0.790) | (0.228,0.790) | (0.868,1.565) | (0.660,1.237) | (0.611,1.192) | ||
| 0 | Reference | Reference | Reference | Reference | Reference | Reference | |
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| 0.038 | 0.0003 |
| 0.0037 | 0.8781 | 0.7441 | |
| IADL | |||||||
| 15 | 0.135 | 0.100 | 0.140 | 0.236 | 0.187 | 0.230 | |
| (0.057,0.323) | (0.041,0.243) | (0.051,0.383) | (0.083,0.667) | (0.065,0.533) | (0.079,0.665) | ||
| 8-14 | 0.702 | 0.584 | 0.643 | 1.053 | 0.900 | 0.935 | |
| (0.371,1.327) | (0.306,1.115) | (0.301,1.370) | (0.558,1.989) | (0.472,1.719) | (0.462,1.894) | ||
| 1-7 | 0.463 | 0.449 | 0.382 | 1.237 | 1.157 | 1.117 | |
| (0.231,0.931) | (0.221,0.911) | (0.164,0.892) | (0.712,2.146) | (0.661,2.023) | (0.604,2.067) | ||
| 0 | Reference | Reference | Reference | Reference | Reference | Reference | |
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| <.0001 | <.0001 |
| 0.0308 | 0.0121 |
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| ADL | |||||||
| 15 | 0.163 | 0.125 | 0.196 | 0.432 | 0.352 | 0.414 | |
| (0.085,0.313) | (0.065,0.243) | (0.095,0.404) | (0.244,0.767) | (0.197,0.631) | (0.223,0.767) | ||
| 8-14 | 0.526 | 0.459 | 0.495 | 0.992 | 0.879 | 0.974 | |
| (0.304,0.910) | (0.263,0.800) | (0.262,0.935) | (0.622,1.581) | (0.547,1.413) | (0.585,1.621) | ||
| 1-7 | 0.569 | 0.545 | 0.494 | 1.032 | 0.953 | 1.011 | |
| (0.328,0.987) | (0.312,0.954) | (0.257,0.947) | (0.672,1.587) | (0.616,1.473) | (0.628,1.628) | ||
| 0 | Reference | Reference | Reference | Reference | Reference | Reference | |
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| <.0001 | <.0001 |
| 0.029 | 0.0054 |
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The reported values indicate odds ratios (95% CI).
Model 1: controlling for age.
Model 2: controlling for marital status, educational level, household income, and a component in Model 1.
Model 3: controlling for chronic disease, BMI, smoking, drinking, and components in Models 1 and 2.
Bold numbers indicate p < 0.05 in final models.
Logistic analysis of work duration and functional status by job category
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| MMSE | ||||||||||
| 15 | 1.168 | 1.098 | 1.174 | 1.107 | 0.825 | 0.803 | 1.136 | 0.869 | 0.950 | |
| (0.569,2.399) | (0.519,2.323) | (0.536,2.572) | (0.895,1.369) | (0.661,1.029) | (0.637,1.012) | (0.724,1.784) | (0.541,1.395) | (0.586,1.542) | ||
| 8-14 | 0.670 | 0.692 | 0.766 | 1.440 | 1.127 | 1.106 | 1.238 | 1.030 | 1.074 | |
| (0.339,1.324) | (0.335,1.432) | (0.356,1.647) | (1.141,1.818) | (0.885,1.434) | (0.861,1.420) | (0.838,1.830) | (0.680,1.559) | (0.702,1.641) | ||
| 1-7 | 0.861 | 0.737 | 0.756 | 1.062 | 0.948 | 0.917 | 1.051 | 0.843 | 0.784 | |
| (0.444,1.670) | (0.365,1.491) | (0.356,1.603) | (0.839,1.345) | (0.744,1.209) | (0.712,1.180) | (0.711,1.554) | (0.560,1.270) | (0.512,1.199) | ||
| 0 | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference | |
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| 0.3908 | 0.4833 | 0.5995 | 0.0119 | 0.0328 |
| 0.7545 | 0.7777 | 0.6219 | |
| IADL | ||||||||||
| 15 | 0.214 | 0.263 | 0.354 | 0.193 | 0.165 | 0.234 | 0.166 | 0.152 | 0.118 | |
| (0.035,1.309) | (0.040,1.718) | (0.040,3.159) | (0.090,0.413) | (0.076,0.355) | (0.101,0.541) | (0.020,1.357) | (0.018,1.255) | (0.013,1.116) | ||
| 8-14 | 0.527 | 0.689 | 1.092 | 1.036 | 0.917 | 0.997 | 0.849 | 0.816 | 0.662 | |
| (0.141,1.968) | (0.178,2.664) | (0.189,6.304) | (0.613,1.751) | (0.538,1.563) | (0.547,1.816) | (0.277,2.607) | (0.257,2.598) | (0.175,2.511) | ||
| 1-7 | 0.277 | 0.358 | 0.212 | 0.802 | 0.790 | 0.841 | 1.412 | 1.332 | 1.149 | |
| (0.066,1.162) | (0.082,1.553) | (0.027,1.685) | (0.469,1.373) | (0.460,1.357) | (0.450,1.572) | (0.581,3.436) | (0.538,3.296) | (0.421,3.134) | ||
| 0 | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference | |
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| 0.2154 | 0.3646 | 0.2798 | 0.0001 | <.0001 |
| 0.2541 | 0.2565 | 0.2595 | |
| ADL | ||||||||||
| 15 | 0.237 | 0.268 | 0.325 | 0.270 | 0.240 | 0.332 | 0.205 | 0.197 | 0.179 | |
| (0.054,1.033) | (0.060,1.202) | (0.062,1.710) | (0.166,0.439) | (0.147,0.393) | (0.197,0.561) | (0.044,0.945) | (0.042,0.915) | (0.034,0.941) | ||
| 8-14 | 0.437 | 0.491 | 0.517 | 0.800 | 0.734 | 0.803 | 0.959 | 0.964 | 1.001 | |
| (0.141,1.350) | (0.158,1.524) | (0.131,2.032) | (0.529,1.211) | (0.482,1.118) | (0.506,1.274) | (0.399,2.303) | (0.391,2.380) | (0.350,2.863) | ||
| 1-7 | 0.405 | 0.456 | 0.331 | 0.857 | 0.830 | 0.876 | 0.977 | 0.923 | 0.875 | |
| (0.136,1.208) | (0.150,1.389) | (0.082,1.331) | (0.574,1.280) | (0.554,1.244) | (0.558,1.377) | (0.437,2.184) | (0.407,2.091) | (0.348,2.198) | ||
| 0 | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference | |
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| 0.1987 | 0.3049 | 0.3759 | <.0001 | <.0001 |
| 0.2261 | 0.2132 | 0.2269 | |
The reported values indicate odds ratios (95% CI).
Model 1: controlling for age and sex.
Model 2: controlling for marital status, educational level, household income, and a component in Model 1.
Model 3: controlling for chronic disease, BMI, smoking, drinking, and components in Models 1 and 2.
Bold numbers indicate p < 0.05 in final models.
Figure 1GAM output of changes in cognitive and physical performances during the past 15 years according to sex. (A) Men’s MMSE; (B) Women’s MMSE; (C) Men’s IADL; (D) Women’s IADL; (E) Men’s ADL; (F) Women’s ADL. The y-axis represents the additive predictor by GAM, which is a smoothed function for each variable and explains the effect of each variable on work duration. The rug-plot on the x-axis represents the number of observations, and dashed lines are the SE +/− 2 confidence bands.
Figure 2GAM output of changes in cognitive and physical performances during the past 15 years according to job categories. (A) Manual worker’s MMSE; (B) Non-manual worker’s MMSE; (C) Other worker‘s MMSE; (D) Manual worker’s IADL; (E) Non-manual worker’s IADL; (F) Other worker‘s IADL; (G) Manual worker’s ADL; (H) Non-manual worker’s ADL; (I) Other worker‘s ADL. The y-axis represents the additive predictor by GAM, which is a smoothed function for each variable and explains the effect of each variable on working duration. The rug-plot on the x-axis represents the number of observations, and dashed lines are the SE +/−2 confidence bands.