| Literature DB >> 25982030 |
Zhenjie Zhang1, Jianying Huang1, Md Robiul Karim1, Jinfeng Zhao1, Haiju Dong1, Weichang Ai2, Fuhuang Li3, Longxian Zhang1, Rongjun Wang4.
Abstract
Enterocytozoon bieneusi is a zoonotic pathogen of the phylum Microspora that infects humans as well as a variety of animal species worldwide. While molecular epidemiologic studies have characterized this parasite in various hosts, isolates from many susceptible hosts have not yet been examined. In this study, E. bieneusi was isolated from 47 Pere David's deer (Elaphurus davidianus) in Henan, China and characterized via PCR analysis of the internal transcribed spacer (ITS) gene. E. bieneusi was detected in 16 out of 47 (34.0%) fecal specimens examined. Sequence analysis of the ITS revealed six known genotypes: type IV (4), EbpC (4), EbpA (4), BEB6 (2), COS-I (1), and COS-II (1). Of these, type IV, EbpC, and EbpA are known to cause human microsporidiosis worldwide, whereas the remaining genotypes are generally specific to ruminants. The present study indicated that Pere David's deer are naturally infected with E. bieneusi, predominantly with zoonotic genotypes, and may pose a risk for human transmission.Entities:
Keywords: Enterocytozoon bieneusi; Genotyping; ITS; Pere David's deer
Mesh：
Year: 2015 PMID： 25982030 DOI： 10.1016/j.exppara.2015.05.008
Source DB: PubMed Journal: Exp Parasitol ISSN： 0014-4894 Impact factor: 2.011