| Literature DB >> 25978870 |
Chidananda Nagamangala Kanchiswamy1, Mickael Malnoy2, Riccardo Velasco2, Jin-Soo Kim3, Roberto Viola2.
Abstract
Direct delivery of purified Cas9 protein with guide RNA into plant cells, as opposed to plasmid-mediated delivery, displays high efficiency and reduced off-target effects. Following regeneration from edited cells, the ensuing plant is also likely to bypass genetically modified organism (GMO) legislation as the genome editing complex is degraded in the recipient cells.Mesh:
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Year: 2015 PMID: 25978870 DOI: 10.1016/j.tibtech.2015.04.002
Source DB: PubMed Journal: Trends Biotechnol ISSN: 0167-7799 Impact factor: 19.536