Literature DB >> 25977056

Nanoemulsion delivery systems for oil-soluble vitamins: Influence of carrier oil type on lipid digestion and vitamin D3 bioaccessibility.

Bengu Ozturk1, Sanem Argin2, Mustafa Ozilgen2, David Julian McClements3.   

Abstract

The influence of carrier oil type on the bioaccessibility of vitamin D3 encapsulated within oil-in-water nanoemulsions prepared using a natural surfactant (quillaja saponin) was studied using a simulated gastrointestinal tract (GIT) model: mouth; stomach; small intestine. The rate of free fatty acid release during lipid digestion decreased in the following order: medium chain triglycerides (MCT) > corn oil ≈ fish oil > orange oil > mineral oil. Conversely, the measured bioaccessibility of vitamin D3 decreased in the following order: corn oil ≈ fish oil > orange oil > mineral oil > MCT. These results show that carrier oil type has a considerable impact on lipid digestion and vitamin bioaccessibility, which was attributed to differences in the release of bioactives from lipid droplets, and their solubilization in mixed micelles. Nanoemulsions prepared using long chain triglycerides (corn or fish oil) were most effective at increasing vitamin bioaccessibility.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Bioaccessibility; Bioavailability; Calcifediol; Calcitriol; Carrier oil; Cholecalciferol; Digestion; Nanoemulsions; Quillaja saponin; Vitamin D(3)

Mesh:

Substances:

Year:  2015        PMID: 25977056     DOI: 10.1016/j.foodchem.2015.04.065

Source DB:  PubMed          Journal:  Food Chem        ISSN: 0308-8146            Impact factor:   7.514


  27 in total

Review 1.  Bioavailability of nanoemulsion formulations vs conventional fat soluble preparations of cholecalciferol (D3) - An overview.

Authors:  Raman Kumar Marwaha; Aashima Dabas
Journal:  J Clin Orthop Trauma       Date:  2019-07-31

2.  The Role of the Food Matrix and Gastrointestinal Tract in the assessment of biological properties of ingested engineered nanomaterials (iENMs): State of the science and knowledge gaps.

Authors:  David Julian McClements; Glen DeLoid; Georgios Pyrgiotakis; Jo Anne Shatkin; Hang Xiao; Philip Demokritou
Journal:  NanoImpact       Date:  2016-10-13

Review 3.  Utilization of Nanotechnology to Improve the Handling, Storage and Biocompatibility of Bioactive Lipids in Food Applications.

Authors:  David Julian McClements; Bengü Öztürk
Journal:  Foods       Date:  2021-02-08

4.  Enhanced oral bioavailability of oligomeric proanthocyanidins by a self-double-emulsifying drug delivery system.

Authors:  Yuan Tian; Xinyu Mao; Rui Sun; Ming Zhang; Qiang Xia
Journal:  Food Sci Nutr       Date:  2020-06-01       Impact factor: 2.863

5.  Stability and in vitro digestibility of beta-carotene in nanoemulsions fabricated with different carrier oils.

Authors:  Xinhui Zhou; Hao Wang; Cuina Wang; Chao Zhao; Qian Peng; Tiehua Zhang; Changhui Zhao
Journal:  Food Sci Nutr       Date:  2018-10-19       Impact factor: 2.863

6.  Evaluation of date palm pollen (Phoenix dactylifera L.) encapsulation, impact on the nutritional and functional properties of fortified yoghurt.

Authors:  Wedad Mohamed El-Kholy; Tarek Nour Soliman; Amira Muhammad Galal Darwish
Journal:  PLoS One       Date:  2019-10-15       Impact factor: 3.240

Review 7.  Nanostructured Lipid-Based Delivery Systems as a Strategy to Increase Functionality of Bioactive Compounds.

Authors:  Ariadna Gasa-Falcon; Isabel Odriozola-Serrano; Gemma Oms-Oliu; Olga Martín-Belloso
Journal:  Foods       Date:  2020-03-11

8.  Development of Turmeric Extract Nanoemulsions and Their Incorporation into Canned Ham.

Authors:  Seung Wook Kim; Coralia V Garcia; Bom Nae Lee; Ho Jeong Kwon; Jun Tae Kim
Journal:  Korean J Food Sci Anim Resour       Date:  2017-12-31       Impact factor: 2.622

9.  β-Sitosterol Loaded Nanostructured Lipid Carrier: Physical and Oxidative Stability, In Vitro Simulated Digestion and Hypocholesterolemic Activity.

Authors:  Yasamin Soleimanian; Sayed Amir Hossein Goli; Jaleh Varshosaz; Lorenzo Di Cesare Mannelli; Carla Ghelardini; Marzia Cirri; Francesca Maestrelli
Journal:  Pharmaceutics       Date:  2020-04-22       Impact factor: 6.321

Review 10.  Development of Next-Generation Nutritionally Fortified Plant-Based Milk Substitutes: Structural Design Principles.

Authors:  David Julian McClements
Journal:  Foods       Date:  2020-04-03
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