Literature DB >> 25972041

Modeling-based determination of physiological parameters of systemic VOCs by breath gas analysis: a pilot study.

Karl Unterkofler1, Julian King, Pawel Mochalski, Martin Jandacka, Helin Koc, Susanne Teschl, Anton Amann, Gerald Teschl.   

Abstract

In this paper we develop a simple two compartment model which extends the Farhi equation to the case when the inhaled concentration of a volatile organic compound (VOC) is not zero. The model connects the exhaled breath concentration of systemic VOCs with physiological parameters such as endogenous production rates and metabolic rates. Its validity is tested with data obtained for isoprene and inhaled deuterated isoprene-D5.

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Year:  2015        PMID： 25972041      PMCID： PMC4909147          DOI： 10.1088/1752-7155/9/3/036002

Source DB:  PubMed          Journal:  J Breath Res        ISSN： 1752-7155            Impact factor:   3.262


  23 in total

1.  Variation in volatile organic compounds in the breath of normal humans.

Authors:  M Phillips; J Herrera; S Krishnan; M Zain; J Greenberg; R N Cataneo
Journal:  J Chromatogr B Biomed Sci Appl       Date:  1999-06-11

2.  A modeling-based evaluation of isothermal rebreathing for breath gas analyses of highly soluble volatile organic compounds.

Authors:  J King; K Unterkofler; G Teschl; S Teschl; P Mochalski; H Koç; H Hinterhuber; A Amann
Journal:  J Breath Res       Date:  2012-01-10       Impact factor: 3.262

3.  Measurement of endogenous acetone and isoprene in exhaled breath during sleep.

Authors:  Julian King; Alexander Kupferthaler; Birgit Frauscher; Heinz Hackner; Karl Unterkofler; Gerald Teschl; Hartmann Hinterhuber; Anton Amann; Birgit Högl
Journal:  Physiol Meas       Date:  2012-02-28       Impact factor: 2.833

4.  Towards standardization in the analysis of breath gas volatiles.

Authors:  Jens Herbig; Jonathan Beauchamp
Journal:  J Breath Res       Date:  2014-09-04       Impact factor: 3.262

5.  Immediate effects of breath holding maneuvers onto composition of exhaled breath.

Authors:  Pritam Sukul; Phillip Trefz; Jochen K Schubert; Wolfram Miekisch
Journal:  J Breath Res       Date:  2014-09-04       Impact factor: 3.262

6.  Clinical breath analysis: discriminating between human endogenous compounds and exogenous (environmental) chemical confounders.

Authors:  Joachim D Pleil; Matthew A Stiegel; Terence H Risby
Journal:  J Breath Res       Date:  2013-02-27       Impact factor: 3.262

7.  A linear model relating breath concentrations to environmental exposures: application to a chamber study of four volunteers exposed to volatile organic chemicals.

Authors:  L Wallace; E Pellizzari; S Gordon
Journal:  J Expo Anal Environ Epidemiol       Date:  1993 Jan-Mar

8.  Breath isoprene: muscle dystrophy patients support the concept of a pool of isoprene in the periphery of the human body.

Authors:  J King; P Mochalski; K Unterkofler; G Teschl; M Klieber; M Stein; A Amann; M Baumann
Journal:  Biochem Biophys Res Commun       Date:  2012-06-05       Impact factor: 3.575

9.  Exhaled methane concentration profiles during exercise on an ergometer.

Authors:  A Szabó; V Ruzsanyi; K Unterkofler; Á Mohácsi; E Tuboly; M Boros; G Szabó; H Hinterhuber; A Amann
Journal:  J Breath Res       Date:  2015-03-09       Impact factor: 3.262

10.  Breath analysis in disease diagnosis: methodological considerations and applications.

Authors:  Célia Lourenço; Claire Turner
Journal:  Metabolites       Date:  2014-06-20
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  4 in total

Review 1.  A Compendium of Volatile Organic Compounds (VOCs) Released By Human Cell Lines.

Authors:  Wojciech Filipiak; Pawel Mochalski; Anna Filipiak; Clemens Ager; Raquel Cumeras; Cristina E Davis; Agapios Agapiou; Karl Unterkofler; Jakob Troppmair
Journal:  Curr Med Chem       Date:  2016       Impact factor: 4.530

2.  Modelling of Breath and Various Blood Volatilomic Profiles-Implications for Breath Volatile Analysis.

Authors:  Paweł Mochalski; Julian King; Chris A Mayhew; Karl Unterkofler
Journal:  Molecules       Date:  2022-04-07       Impact factor: 4.411

3.  Prediction of blood:air and fat:air partition coefficients of volatile organic compounds for the interpretation of data in breath gas analysis.

Authors:  Christian Kramer; Paweł Mochalski; Karl Unterkofler; Agapios Agapiou; Veronika Ruzsanyi; Klaus R Liedl
Journal:  J Breath Res       Date:  2016-01-27       Impact factor: 3.262

4.  Modeling of breath methane concentration profiles during exercise on an ergometer.

Authors:  Anna Szabó; Karl Unterkofler; Pawel Mochalski; Martin Jandacka; Vera Ruzsanyi; Gábor Szabó; Árpád Mohácsi; Susanne Teschl; Gerald Teschl; Julian King
Journal:  J Breath Res       Date:  2016-02-01       Impact factor: 3.262
  4 in total

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