Literature DB >> 25963916

Binding of Anticell Adhesive Oxime-Crosslinked PEG Hydrogels to Cardiac Tissues.

Gregory N Grover1, Julian Garcia1, Mary M Nguyen1, Matthew Zanotelli1, Michael M Madani2, Karen L Christman1.   

Abstract

Postsurgical cardiac adhesions increase the number of surgeries as well as patient mortality and morbidity. A fast gelling oxime-crosslinked PEG hydrogel with tunable gelation time, degradation, and mechanical properties is presented. This material is cytocompatible and prevents cellular adhesion. Material retention on different cardiac tissues is demonstrated ex vivo over time and that functional group ratio alters material retention on different cardiac tissues.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  cardiac surgery; hydrogels; postsurgical adhesions

Mesh：

Substances：

Year:  2015        PMID： 25963916      PMCID： PMC5812365          DOI： 10.1002/adhm.201500167

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


  21 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  2017-08-14       Impact factor: 11.205

2.  Preventing post-surgical cardiac adhesions with a catechol-functionalized oxime hydrogel.

Authors:  Masaki Fujita; Gina M Policastro; Austin Burdick; Hillary T Lam; Jessica L Ungerleider; Rebecca L Braden; Diane Huang; Kent G Osborn; Jeffrey H Omens; Michael M Madani; Karen L Christman
Journal:  Nat Commun       Date:  2021-06-18       Impact factor: 14.919
  2 in total

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