Literature DB >> 23495015

Oxime cross-linked injectable hydrogels for catheter delivery.

Gregory N Grover1, Rebecca L Braden, Karen L Christman.   

Abstract

Catheter delivery of therapeutic materials is important for developing minimally invasive treatment approaches. However, the majority of injectable materials gel rapidly upon mixing and/or heating to body temperature. The application of an oxime cross-linked hydrogel system is demonstrated. The system has a broad range of tunable gelation rates, is capable of injection through a catheter, and exhibits rapid gelation upon injection into tissue.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  catheters; injectable hydrogels; oxime cross-linking

Mesh:

Substances:

Year:  2013        PMID: 23495015      PMCID: PMC3884068          DOI: 10.1002/adma.201205234

Source DB:  PubMed          Journal:  Adv Mater        ISSN: 0935-9648            Impact factor:   30.849


  34 in total

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