Elizabeth M Cespedes1,2, Katherine A Dudley3, Daniela Sotres-Alvarez4, Phyllis C Zee5,6, Martha L Daviglus5,6, Neomi A Shah7, Gregory A Talavera8, Linda C Gallo9, Josiemer Mattei1, Qibin Qi10, Alberto R Ramos11, Neil Schneiderman12, Rebeca A Espinoza-Giacinto13, Sanjay R Patel3. 1. Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA. 2. Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA. 3. Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts, USA. 4. Department of Biostatistics, Collaborative Studies Coordinating Center, University of North Carolina, Chapel Hill, North Carolina, USA. 5. Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA. 6. Institute for Minority Health Research, University of Illinois at Chicago, Chicago, Illinois, USA. 7. Montefiore Medical Center, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York, USA. 8. Division of Health Promotion and Behavioral Science, Graduate School of Public Health, San Diego State University, San Diego, California, USA. 9. Departments of Psychology, University of California San Diego, San Diego, California, USA. 10. Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA. 11. Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida, USA. 12. Department of Psychology, University of Miami, Coral Gables, Florida, USA. 13. Medicine, Division of Global Public Health, University of California San Diego, San Diego, California, USA.
Abstract
BACKGROUND: Inadequate sleep quantity and quality are associated with a higher risk of type 2 diabetes. This relationship is not well-examined in U.S. Hispanics/Latinos, and prior analyses may be confounded by sleep apnea. This cross-sectional study examined joint associations of sleep duration and insomnia with diabetes among diverse U.S. Hispanic/Latinos. METHODS: Baseline data on sleep quantity and quality were obtained from 15,227 participants (mean age 41; range 18-74 years) from the Hispanic Community Health Study/Study of Latinos. Complex survey multinomial logistic regression was used to examine associations between prevalent diabetes and six phenotypes defined by cross-classifying sleep duration (short ≤6 h, average >6-9 h, long >9 h) and insomnia, adjusting for sex, age, site and Hispanic/Latino background interaction, education, physical activity, diet quality, and sleep apnea. RESULTS: In the weighted population, 14% had diabetes, 28% had insomnia, 9% were short sleepers, and 19% were long sleepers. Compared with those with average sleep and no insomnia, those with short sleep and insomnia were more likely to have diabetes (odds ratio [OR] 1.46; 95% confidence interval [CI] 1.02, 2.11). Average sleepers with insomnia (1.28; 95% CI 1.02, 1.61) and long sleepers without insomnia (1.33; 95% CI 1.07, 1.65) also had elevated odds of diabetes. Further adjustment for body mass index attenuated associations, except with long sleep without insomnia. CONCLUSIONS: Both decreased quantity and quality of sleep are associated with diabetes in Hispanic/Latinos, with the greatest odds among those with short sleep duration and insomnia. The association is largely explained by obesity.
BACKGROUND: Inadequate sleep quantity and quality are associated with a higher risk of type 2 diabetes. This relationship is not well-examined in U.S. Hispanics/Latinos, and prior analyses may be confounded by sleep apnea. This cross-sectional study examined joint associations of sleep duration and insomnia with diabetes among diverse U.S. Hispanic/Latinos. METHODS: Baseline data on sleep quantity and quality were obtained from 15,227 participants (mean age 41; range 18-74 years) from the Hispanic Community Health Study/Study of Latinos. Complex survey multinomial logistic regression was used to examine associations between prevalent diabetes and six phenotypes defined by cross-classifying sleep duration (short ≤6 h, average >6-9 h, long >9 h) and insomnia, adjusting for sex, age, site and Hispanic/Latino background interaction, education, physical activity, diet quality, and sleep apnea. RESULTS: In the weighted population, 14% had diabetes, 28% had insomnia, 9% were short sleepers, and 19% were long sleepers. Compared with those with average sleep and no insomnia, those with short sleep and insomnia were more likely to have diabetes (odds ratio [OR] 1.46; 95% confidence interval [CI] 1.02, 2.11). Average sleepers with insomnia (1.28; 95% CI 1.02, 1.61) and long sleepers without insomnia (1.33; 95% CI 1.07, 1.65) also had elevated odds of diabetes. Further adjustment for body mass index attenuated associations, except with long sleep without insomnia. CONCLUSIONS: Both decreased quantity and quality of sleep are associated with diabetes in Hispanic/Latinos, with the greatest odds among those with short sleep duration and insomnia. The association is largely explained by obesity.
Authors: Sabra M Abbott; Jia Weng; Kathryn J Reid; Martha L Daviglus; Linda C Gallo; Jose S Loredo; Sharmilee M Nyenhuis; Alberto R Ramos; Neomi A Shah; Daniela Sotres-Alvarez; Sanjay R Patel; Phyllis C Zee Journal: Chest Date: 2018-10-06 Impact factor: 9.410
Authors: Jinsong Chen; Sanjay R Patel; Susan Redline; Ramon Durazo-Arvizu; Daniel B Garside; Kathryn J Reid; James Lash; Daniela Sotres-Alvarez; Linda C Gallo; Megan E Petrov; Krista M Perreira; Gregory A Talavera; Alberto R Ramos; Phyllis Zee; Martha L Daviglus Journal: Sleep Date: 2018-10-01 Impact factor: 5.849
Authors: Alberto R Ramos; Wassim Tarraf; Benson Wu; Susan Redline; Jianwen Cai; Martha L Daviglus; Linda Gallo; Yasmin Mossavar-Rahmani; Krista M Perreira; Phyllis Zee; Donglin Zeng; Hector M Gonzalez Journal: Alzheimers Dement Date: 2020-01-06 Impact factor: 21.566
Authors: Daria M McMahon; James B Burch; Michael D Wirth; Shawn D Youngstedt; James W Hardin; Thomas G Hurley; Steven N Blair; Gregory A Hand; Robin P Shook; Clemens Drenowatz; Stephanie Burgess; James R Hebert Journal: Chronobiol Int Date: 2017-12-12 Impact factor: 2.877