Xu Han1, Yiheng Yang1, Yue Chen1, Lianjun Gao1, Xiaomeng Yin1, Huihua Li2, Jing Qiu3, Youxin Wang4, Yong Zhou5, Yunlong Xia1. 1. Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, China. 2. Institute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian, China. 3. Human Resource, Wuhan Hospital of Traditional Chinese Medicine, Wuhan, China. 4. Beijing Municipal Key Laboratory of Clinical Epidemiology, School of Public Health, Capital Medical University, Beijing, China. 5. Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Abstract
BACKGROUND: Insomnia is the most prevalent sleep disorder; however, little research has explored the link between insomnia and atrial fibrillation (AF). HYPOTHESIS: Insomnia is associated with increased risk of AF in a Chinese population. METHODS: A total of 8371 Chinese participants (4314 males; mean age, 42.4 ± 13.1 years) were enrolled in this cross-sectional study to investigate the association between insomnia and AF. AF was assessed in a standard supine resting position with a 10-s 12-lead electrocardiograph (ECG) or by self-reported history. Insomnia was assessed using the Athens Insomnia Scale (AIS), and a score of ≥6 was regarded as having insomnia. The association between insomnia and AF was determined by logistic regression analysis. RESULTS: Among the 8371 subjects, 1074 (12.8%) had different degrees of insomnia, and AF was observed in 50 subjects (0.60%). After adjusting for potential confounders, individuals with insomnia had moderately increased likelihood of suffering from AF compared with those without insomnia (odds ratio [OR]: 1.92, 95% confidence interval [CI]: 1.00-3.70, P = 0.05). After stratifying data by age, a significant positive association was found in those age <40 years (OR: 6.52, 95% CI: 1.64-25.83, P = 0.01), and a similar trend existed in males after stratifying by sex, although this relationship was not statistically significant (OR: 2.11, 95% CI: 0.92-4.83, P = 0.08). CONCLUSIONS: Individuals with insomnia may have a higher risk of AF in the particular Chinese population assessed in this study. Age (<40 years) is a significant factor in the association between insomnia and AF.
BACKGROUND:Insomnia is the most prevalent sleep disorder; however, little research has explored the link between insomnia and atrial fibrillation (AF). HYPOTHESIS: Insomnia is associated with increased risk of AF in a Chinese population. METHODS: A total of 8371 Chinese participants (4314 males; mean age, 42.4 ± 13.1 years) were enrolled in this cross-sectional study to investigate the association between insomnia and AF. AF was assessed in a standard supine resting position with a 10-s 12-lead electrocardiograph (ECG) or by self-reported history. Insomnia was assessed using the Athens Insomnia Scale (AIS), and a score of ≥6 was regarded as having insomnia. The association between insomnia and AF was determined by logistic regression analysis. RESULTS: Among the 8371 subjects, 1074 (12.8%) had different degrees of insomnia, and AF was observed in 50 subjects (0.60%). After adjusting for potential confounders, individuals with insomnia had moderately increased likelihood of suffering from AF compared with those without insomnia (odds ratio [OR]: 1.92, 95% confidence interval [CI]: 1.00-3.70, P = 0.05). After stratifying data by age, a significant positive association was found in those age <40 years (OR: 6.52, 95% CI: 1.64-25.83, P = 0.01), and a similar trend existed in males after stratifying by sex, although this relationship was not statistically significant (OR: 2.11, 95% CI: 0.92-4.83, P = 0.08). CONCLUSIONS: Individuals with insomnia may have a higher risk of AF in the particular Chinese population assessed in this study. Age (<40 years) is a significant factor in the association between insomnia and AF.
Authors: Michael Littner; Max Hirshkowitz; Milton Kramer; Sheldon Kapen; W McDowell Anderson; Dennis Bailey; Richard B Berry; David Davila; Stephen Johnson; Clete Kushida; Daniel I Loube; Merrill Wise; B Tucker Woodson Journal: Sleep Date: 2003-09 Impact factor: 5.849
Authors: Ronnier J Aviles; David O Martin; Carolyn Apperson-Hansen; Penny L Houghtaling; Pentti Rautaharju; Richard A Kronmal; Russell P Tracy; David R Van Wagoner; Bruce M Psaty; Michael S Lauer; Mina K Chung Journal: Circulation Date: 2003-11-17 Impact factor: 29.690
Authors: Nancy S Redeker; Samantha Conley; George Anderson; John Cline; Laura Andrews; Vahid Mohsenin; Daniel Jacoby; Sangchoon Jeon Journal: Behav Sleep Med Date: 2018-11-21 Impact factor: 2.964