Literature DB >> 30053253

Weekly sleep trajectories and their associations with obesity and hypertension in the Hispanic/Latino population.

Jinsong Chen1, Sanjay R Patel2, Susan Redline3, Ramon Durazo-Arvizu1, Daniel B Garside1, Kathryn J Reid4, James Lash1, Daniela Sotres-Alvarez5, Linda C Gallo6, Megan E Petrov7, Krista M Perreira5, Gregory A Talavera6, Alberto R Ramos8, Phyllis Zee4, Martha L Daviglus1.   

Abstract

Study
Objectives: To identify weekly sleep trajectories (sleep pattern changing by day over a course of week) of specific characteristics and examine the associations between trajectory classes and obesity and hypertension.
Methods: A total of 2043 participants (mean age 46.9, 65.5% female) completed at least 7 days of actigraphy aged 18-64 from the Sueño ancillary study of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Weekly sleep trajectories for three daily level measures (wake after sleep onset [WASO], daytime napping duration, and intranight instability index) were identified using latent class growth models. The outcomes were obesity and hypertension.
Results: Using the trajectory with low-stable WASO as reference, the trajectory classes with increasing and high-concave patterns had significantly higher odds for obesity (OR 3.64 [1.23-10.84]) and hypertension (OR 5.25 [1.33, 20.82]), respectively. Compared with individuals with a low-stable napping duration trajectory, those with the high-concave pattern class were associated with hypertension (OR 2.27 [1.10-4.67]), and the association was mediated in part by obesity (OR 1.11 [1.00-1.22]). Individuals in the high intranight instability index trajectory had significantly larger likelihood for both obesity (OR 1.90 [1.26-2.86]) and hypertension (OR 1.86 [1.13-3.06]) compared with those in the low intranight instability index trajectory. Conclusions: Weekly trajectories varied for WASO, daytime napping duration, and intranight instability index. The trajectories with relatively larger values for these three measures were associated with greater risk for obesity and hypertension. These findings suggest that a stable pattern with relatively small weekly and nightly variability may be beneficial for cardiovascular health.

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Year:  2018        PMID: 30053253      PMCID: PMC6187108          DOI: 10.1093/sleep/zsy150

Source DB:  PubMed          Journal:  Sleep        ISSN: 0161-8105            Impact factor:   5.849


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