Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Endogenous neurogenic cell response in the mature mammalian brain following traumatic injury.

Literature DB >> 25936874

Endogenous neurogenic cell response in the mature mammalian brain following traumatic injury.

Abstract

In the mature mammalian brain, new neurons are generated throughout life in the neurogenic regions of the subventricular zone (SVZ) and the dentate gyrus (DG) of the hippocampus. Over the past two decades, extensive studies have examined the extent of adult neurogenesis in the SVZ and DG, the role of the adult generated new neurons in normal brain function and the underlying mechanisms regulating the process of adult neurogenesis. The extent and the function of adult neurogenesis under neuropathological conditions have also been explored in varying types of disease models in animals. Increasing evidence has indicated that these endogenous neural stem/progenitor cells may play regenerative and reparative roles in response to CNS injuries or diseases. This review will discuss the potential functions of adult neurogenesis in the injured brain and will describe the recent development of strategies aimed at harnessing this neurogenic capacity in order to repopulate and repair the injured brain following trauma.

Entities: Chemical Disease Gene Species

Keywords: Cognitive function; Endogenous neurogenesis; Hippocampus; Subventricular zone; Traumatic brain injury

Mesh：

Year: 2015 PMID： 25936874 PMCID： PMC4627904 DOI： 10.1016/j.expneurol.2015.04.017

Source DB: PubMed Journal: Exp Neurol ISSN： 0014-4886 Impact factor: 5.330

113 in total

1. Adult-generated hippocampal and neocortical neurons in macaques have a transient existence.

Authors: E Gould; N Vail; M Wagers; C G Gross
Journal: Proc Natl Acad Sci U S A Date: 2001-08-28 Impact factor: 11.205

2. Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain.

Authors: H G Kuhn; J Winkler; G Kempermann; L J Thal; F H Gage
Journal: J Neurosci Date: 1997-08-01 Impact factor: 6.167

3. Olfactory perceptual learning requires adult neurogenesis.

Authors: Mélissa M Moreno; Christiane Linster; Olga Escanilla; Joëlle Sacquet; Anne Didier; Nathalie Mandairon
Journal: Proc Natl Acad Sci U S A Date: 2009-10-07 Impact factor: 11.205

4. Adrenal steroids suppress granule cell death in the developing dentate gyrus through an NMDA receptor-dependent mechanism.

Authors: E Gould; P Tanapat; H A Cameron
Journal: Brain Res Dev Brain Res Date: 1997-10-20

5. Dynamics of hippocampal neurogenesis in adult humans.

Authors: Kirsty L Spalding; Olaf Bergmann; Kanar Alkass; Samuel Bernard; Mehran Salehpour; Hagen B Huttner; Emil Boström; Isabelle Westerlund; Celine Vial; Bruce A Buchholz; Göran Possnert; Deborah C Mash; Henrik Druid; Jonas Frisén
Journal: Cell Date: 2013-06-06 Impact factor: 41.582

6. Importance of newly generated neurons in the adult olfactory bulb for odor discrimination.

Authors: G Gheusi; H Cremer; H McLean; G Chazal; J D Vincent; P M Lledo
Journal: Proc Natl Acad Sci U S A Date: 2000-02-15 Impact factor: 11.205

7. Short-term and long-term survival of new neurons in the rat dentate gyrus.

Authors: Alexandre G Dayer; Abigail A Ford; Kathryn M Cleaver; Mina Yassaee; Heather A Cameron
Journal: J Comp Neurol Date: 2003-06-09 Impact factor: 3.215

8. EphrinB3 regulates cell proliferation and survival in adult neurogenesis.

Authors: Jerome Ricard; Jessica Salinas; Lissette Garcia; Daniel J Liebl
Journal: Mol Cell Neurosci Date: 2006-02-17 Impact factor: 4.314

9. A small molecule p75(NTR) ligand protects neurogenesis after traumatic brain injury.

Authors: Jian Shi; Frank M Longo; Stephen M Massa
Journal: Stem Cells Date: 2013-11 Impact factor: 6.277

10. Neurogenesis and glial proliferation persist for at least one year in the subventricular zone following brain trauma in rats.

Authors: Xiao-Han Chen; Akira Iwata; Masahiro Nonaka; Kevin D Browne; Douglas H Smith
Journal: J Neurotrauma Date: 2003-07 Impact factor: 5.269

23 in total

10. Impact of siRNA targeting of β-catenin on differentiation of rat neural stem cells and gene expression of Ngn1 and BMP4 following in vitro hypoxic-ischemic brain damage.

Authors: Xiaoying Zhang; Cuicui Zhu; Qiong Luo; Jv Dong; Lv Liu; Min Li; Hongtao Zhu; Xiangping Ma; Jun Wang
Journal: Mol Med Rep Date: 2016-08-24 Impact factor: 2.952

Endogenous neurogenic cell response in the mature mammalian brain following traumatic injury.

1. Adult-generated hippocampal and neocortical neurons in macaques have a transient existence.

2. Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain.

3. Olfactory perceptual learning requires adult neurogenesis.

4. Adrenal steroids suppress granule cell death in the developing dentate gyrus through an NMDA receptor-dependent mechanism.

5. Dynamics of hippocampal neurogenesis in adult humans.

6. Importance of newly generated neurons in the adult olfactory bulb for odor discrimination.

7. Short-term and long-term survival of new neurons in the rat dentate gyrus.

8. EphrinB3 regulates cell proliferation and survival in adult neurogenesis.

9. A small molecule p75(NTR) ligand protects neurogenesis after traumatic brain injury.

10. Neurogenesis and glial proliferation persist for at least one year in the subventricular zone following brain trauma in rats.

Review 1. Modes of division and differentiation of neural stem cells.

2. miR-124-3p is a chronic regulator of gene expression after brain injury.

Review 3. Strategies targeting endogenous neurogenic cell response to improve recovery following traumatic brain injury.

Review 4. The role of autoimmunity in pituitary dysfunction due to traumatic brain injury.

Review 5. Therapeutic Application of Stem Cells in the Repair of Traumatic Brain Injury.

Review 6. The Potential of Stem Cells in Treatment of Traumatic Brain Injury.

7. Polyplex transfection from intracerebroventricular delivery is not significantly affected by traumatic brain injury.

Review 8. Physiological, pathological, and engineered cell identity reprogramming in the central nervous system.

9. Heterogeneous generation of new cells in the adult echinoderm nervous system.

10. Impact of siRNA targeting of β-catenin on differentiation of rat neural stem cells and gene expression of Ngn1 and BMP4 following in vitro hypoxic-ischemic brain damage.