Literature DB >> 25932775

A thermostable archaeal S-adenosylmethionine synthetase: a promising tool to improve the synthesis of adenosylmethionine analogs of biotechnological interest.

Marina Porcelli1, Concetta Paola Ilisso, Laura Mosca, Giovanna Cacciapuoti.   

Abstract

The naturally and widely occurring sulfonium compound, S-adenosylmethionine (AdoMet), one of nature's most versatile molecules, is biosynthesized from methionine and ATP by AdoMet synthetase or methionine adenosyltransferase (MAT) in a 2-step reaction in which the energy-rich sulfonium compound is formed by dephosphorylation of ATP. All living cells, with the only exception of some parasites and infectious agents, express MAT.

Entities:  

Keywords:  AdoMet, S-Adenosylmethionine; Archaea; BsMAT, MAT from Bacillus subtilis; DMSO, dimethylsulfoxide; MAT, adenosylmethionine synthetase or methionine adenosyltransferase; EcMAT, MAT from E. coli.; MjMAT, MAT from Methanococcus jannaschii; PfMAT, MAT from Pyrococcus furiosus; Pyrococcus furiosus; S-Adenosylmethionine; SsMAT, MAT from Sulfolobus solfataricus; TkMAT, MAT from Thermococcus kodakarensis; adenosylmethionine synthetase; hyperthermophilic enzymes; methionine adenosyltransferase; organic solvent activity and thermostability

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Year:  2015        PMID: 25932775      PMCID: PMC4601474          DOI: 10.1080/21655979.2015.1045170

Source DB:  PubMed          Journal:  Bioengineered        ISSN: 2165-5979            Impact factor:   3.269


  15 in total

Review 1.  Improving enzymes by using them in organic solvents.

Authors:  A M Klibanov
Journal:  Nature       Date:  2001-01-11       Impact factor: 49.962

2.  Structural and kinetic properties of Bacillus subtilis S-adenosylmethionine synthetase expressed in Escherichia coli.

Authors:  Venu Kamarthapu; Khareedu Venkateswara Rao; P N B S Srinivas; G Bhanuprakash Reddy; Vudem Dashavantha Reddy
Journal:  Biochim Biophys Acta       Date:  2008-06-19

3.  Effects of S-adenosylmethionine and methylthioadenosine on inflammation-induced colon cancer in mice.

Authors:  Tony W H Li; Heping Yang; Hui Peng; Meng Xia; José M Mato; Shelly C Lu
Journal:  Carcinogenesis       Date:  2011-12-09       Impact factor: 4.944

Review 4.  S-Adenosylmethionine: a control switch that regulates liver function.

Authors:  Jose M Mato; Fernando J Corrales; Shelly C Lu; Matias A Avila
Journal:  FASEB J       Date:  2002-01       Impact factor: 5.191

5.  Enzymatic properties of S-adenosylmethionine synthetase from the archaeon Methanococcus jannaschii.

Authors:  Zichun J Lu; George D Markham
Journal:  J Biol Chem       Date:  2002-02-28       Impact factor: 5.157

Review 6.  S-Adenosylmethionine.

Authors:  S C Lu
Journal:  Int J Biochem Cell Biol       Date:  2000-04       Impact factor: 5.085

Review 7.  S-adenosylmethionine in liver health, injury, and cancer.

Authors:  Shelly C Lu; José M Mato
Journal:  Physiol Rev       Date:  2012-10       Impact factor: 37.312

8.  S-Adenosylmethionine synthetase from Escherichia coli.

Authors:  G D Markham; E W Hafner; C W Tabor; H Tabor
Journal:  J Biol Chem       Date:  1980-10-10       Impact factor: 5.157

9.  Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus.

Authors:  Fengbin Wang; Shanteri Singh; Jianjun Zhang; Tyler D Huber; Kate E Helmich; Manjula Sunkara; Katherine A Hurley; Randal D Goff; Craig A Bingman; Andrew J Morris; Jon S Thorson; George N Phillips
Journal:  FEBS J       Date:  2014-04-07       Impact factor: 5.542

10.  Structural and functional characterisation of the methionine adenosyltransferase from Thermococcus kodakarensis.

Authors:  Julia Schlesier; Jutta Siegrist; Stefan Gerhardt; Annette Erb; Simone Blaesi; Michael Richter; Oliver Einsle; Jennifer N Andexer
Journal:  BMC Struct Biol       Date:  2013-10-18
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  3 in total

1.  S-Adenosylmethionine regulates apoptosis and autophagy in MCF-7 breast cancer cells through the modulation of specific microRNAs.

Authors:  Concetta Paola Ilisso; Donatella Delle Cave; Laura Mosca; Martina Pagano; Alessandra Coppola; Luigi Mele; Michele Caraglia; Giovanna Cacciapuoti; Marina Porcelli
Journal:  Cancer Cell Int       Date:  2018-12-04       Impact factor: 5.722

2.  S-Adenosyl-l-Methionine Overcomes uL3-Mediated Drug Resistance in p53 Deleted Colon Cancer Cells.

Authors:  Laura Mosca; Martina Pagano; Annalisa Pecoraro; Luigi Borzacchiello; Luigi Mele; Giovanna Cacciapuoti; Marina Porcelli; Giulia Russo; Annapina Russo
Journal:  Int J Mol Sci       Date:  2020-12-24       Impact factor: 6.208

Review 3.  Methyltransferases: Functions and Applications.

Authors:  Eman Abdelraheem; Benjamin Thair; Romina Fernández Varela; Emely Jockmann; Désirée Popadić; Helen C Hailes; John M Ward; Adolfo M Iribarren; Elizabeth S Lewkowicz; Jennifer N Andexer; Peter-Leon Hagedoorn; Ulf Hanefeld
Journal:  Chembiochem       Date:  2022-07-05       Impact factor: 3.461

  3 in total

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