Literature DB >> 2592421

Regulation of bone sialoprotein mRNA by steroid hormones.

A Oldberg1, B Jirskog-Hed, S Axelsson, D Heinegård.   

Abstract

In this report we demonstrate an increase in the steady-state level of bone sialoprotein (BSP) mRNA in rat calvaria and a rat osteosarcoma cell line (ROS 17/2.8) after treatment with the synthetic glucocorticoid, dexamethasone. In contrast, 1.25-dihydroxyvitamin D3 reduced the amount of BSP mRNA in calvaria and inhibited the dexamethasone induction in ROS 17/2.8 cells. The increase in BSP mRNA is most likely due to an increase in the transcriptional rate. The stability of mRNA was unchanged after dexamethasone treatment with a half-life of approximately 5 h. Nuclear transcription experiments with nuclei isolated from ROS 17/2.8 cells showed an increased BSP mRNA synthesis in cells treated with dexamethasone.

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Year:  1989        PMID： 2592421      PMCID： PMC2115918          DOI： 10.1083/jcb.109.6.3183

Source DB:  PubMed          Journal:  J Cell Biol        ISSN： 0021-9525            Impact factor:   10.539


  11 in total

1.  Identification of a bone sialoprotein receptor in osteosarcoma cells.

Authors:  A Oldberg; A Franzén; D Heinegård; M Pierschbacher; E Ruoslahti
Journal:  J Biol Chem       Date:  1988-12-25       Impact factor: 5.157

2.  Chondrocyte-matrix interactions. Attachment to proteins isolated from cartilage.

Authors:  Y Sommarin; T Larsson; D Heinegård
Journal:  Exp Cell Res       Date:  1989-09       Impact factor: 3.905

3.  Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene.

Authors:  M E Greenberg; E B Ziff
Journal:  Nature       Date:  1984 Oct 4-10       Impact factor: 49.962

4.  Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence.

Authors:  A Oldberg; A Franzén; D Heinegård
Journal:  Proc Natl Acad Sci U S A       Date:  1986-12       Impact factor: 11.205

5.  Dexamethasone stimulates osteogenesis in chick periosteum in vitro.

Authors:  H C Tenenbaum; J N Heersche
Journal:  Endocrinology       Date:  1985-11       Impact factor: 4.736

6.  Mechanism of action of DRB. III. Effect on specific in vitro initiation of transcription.

Authors:  R Zandomeni; D Bunick; S Ackerman; B Mittleman; R Weinmann
Journal:  J Mol Biol       Date:  1983-07-05       Impact factor: 5.469

7.  Purification and partial characterization of small proteoglycans I and II, bone sialoproteins I and II, and osteonectin from the mineral compartment of developing human bone.

Authors:  L W Fisher; G R Hawkins; N Tuross; J D Termine
Journal:  J Biol Chem       Date:  1987-07-15       Impact factor: 5.157

8.  Parathyroid hormone-responsive clonal cell lines from rat osteosarcoma.

Authors:  R J Majeska; S B Rodan; G A Rodan
Journal:  Endocrinology       Date:  1980-11       Impact factor: 4.736

9.  Tissue specificity and developmental expression of rat osteopontin.

Authors:  K Yoon; R Buenaga; G A Rodan
Journal:  Biochem Biophys Res Commun       Date:  1987-11-13       Impact factor: 3.575

10.  Enhanced transcription of c-myc in bursal lymphoma cells requires continuous protein synthesis.

Authors:  M Linial; N Gunderson; M Groudine
Journal:  Science       Date:  1985-12-06       Impact factor: 47.728
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  15 in total

Review 1.  Tissue specific and vitamin D responsive gene expression in bone.

Authors:  C White; E Gardiner; J Eisman
Journal:  Mol Biol Rep       Date:  1998-01       Impact factor: 2.316

2.  In vitro and in vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism.

Authors:  T Meyer; M Kneissel; J Mariani; B Fournier
Journal:  Proc Natl Acad Sci U S A       Date:  2000-08-01       Impact factor: 11.205

3.  Stimulation by bone sialoprotein of calcification in osteoblast-like MC3T3-E1 cells.

Authors:  H Y Zhou; H Takita; R Fujisawa; M Mizuno; Y Kuboki
Journal:  Calcif Tissue Int       Date:  1995-05       Impact factor: 4.333

4.  Further characterization of interaction between bone sialoprotein (BSP) and collagen.

Authors:  R Fujisawa; Y Nodasaka; Y Kuboki
Journal:  Calcif Tissue Int       Date:  1995-02       Impact factor: 4.333

5.  Modulation of bone resorption by phosphorylation state of bone sialoprotein.

Authors:  Paul Curtin; Kevin P McHugh; Hai-Yan Zhou; Rudolf Flückiger; Paul Goldhaber; Frank G Oppenheim; Erdjan Salih
Journal:  Biochemistry       Date:  2009-07-28       Impact factor: 3.162

6.  Gene expression and distribution of key bone turnover markers in the callus of estrogen-deficient, vitamin D-depleted rats.

Authors:  Gunhild Melhus; S H Brorson; E S Baekkevold; G Andersson; R Jemtland; O K Olstad; F P Reinholt
Journal:  Calcif Tissue Int       Date:  2010-05-22       Impact factor: 4.333

7.  Bone sialoprotein mRNA expression and ultrastructural localization in fetal porcine calvarial bone: comparisons with osteopontin.

Authors:  J Chen; M D McKee; A Nanci; J Sodek
Journal:  Histochem J       Date:  1994-01

8.  Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells.

Authors:  Kai Cai; Natasha C Lucki; Marion B Sewer
Journal:  Biochim Biophys Acta       Date:  2013-12-22

9.  Serum concentrations of cartilage oligomeric matrix protein and bone sialoprotein in hip osteoarthritis: a one year prospective study.

Authors:  T Conrozier; T Saxne; C S Fan; P Mathieu; A M Tron; D Heinegård; E Vignon
Journal:  Ann Rheum Dis       Date:  1998-09       Impact factor: 19.103

10.  Cloning and characterization of the rat bone sialoprotein gene promoter.

Authors:  J J Li; J Sodek
Journal:  Biochem J       Date:  1993-02-01       Impact factor: 3.857
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