Hyungjin Kim1,2,3, Chang Min Park4,5,6, Sang Min Lee1,2, Jin Mo Goo1,2,7. 1. Department of Radiology, Seoul National University College of Medicine, 101, Daehangno, Jongno-gu, Seoul, 110-744, Korea. 2. Institute of Radiation Medicine, Seoul National University Medical Research Center, 101, Daehangno, Jongno-gu, Seoul, 110-744, Korea. 3. Aerospace Medical Group, Air Force Education and Training Command, Jinju, Korea. 4. Department of Radiology, Seoul National University College of Medicine, 101, Daehangno, Jongno-gu, Seoul, 110-744, Korea. cmpark.morphius@gmail.com. 5. Institute of Radiation Medicine, Seoul National University Medical Research Center, 101, Daehangno, Jongno-gu, Seoul, 110-744, Korea. cmpark.morphius@gmail.com. 6. Cancer Research Institute, Seoul National University, 101, Daehangno, Jongno-gu, Seoul, 110-744, Korea. cmpark.morphius@gmail.com. 7. Cancer Research Institute, Seoul National University, 101, Daehangno, Jongno-gu, Seoul, 110-744, Korea.
Abstract
OBJECTIVES: To assess the usefulness of C-arm cone-beam computed tomography (CBCT) virtual navigation-guided percutaneous mediastinal mass biopsy in terms of diagnostic accuracy and complication rates. METHODS: Seventy-eight CBCT virtual navigation-guided percutaneous mediastinal mass biopsies were performed in 75 patients (M:F, 38:37; mean age, 48.55 ± 18.76 years). The procedural details, diagnostic sensitivity, specificity, accuracy and complication rate were investigated. RESULTS: Mean lesion size was 6.80 ± 3.08 cm, skin-to-target distance was 3.67 ± 1.80 cm, core needle biopsy rate was 96.2 % (75/78), needle indwelling time was 9.29 ± 4.34 min, total procedure time was 13.26 ± 5.29 min, number of biopsy specimens obtained was 3.13 ± 1.02, number of CBCTs performed was 3.03 ± 0.68, rate of lesion border discrimination from abutting mediastinal structures on CBCT was 26.9 % (21/78), technical success rate was 100 % (78/78), estimated effective dose was 5.33 ± 4.99 mSv, and the dose area product was 12,723.68 ± 10,665.74 mGy⋅cm(2). Among the 78 biopsies, 69 were malignant, 7 were benign and 2 were indeterminate. Diagnostic sensitivity, specificity and accuracy for the diagnosis of malignancies were 97.1 % (67/69), 100 % (7/7) and 97.4 % (74/76), respectively, with a complication rate of 3.85 % (3/78), all of which were small pneumothoraces. CONCLUSIONS: CBCT virtual navigation-guided biopsy is a highly accurate and safe procedure for the evaluation of mediastinal lesions. KEY POINTS: • CBCT virtual navigation-guided percutaneous mediastinal biopsy is highly accurate • CBCT virtual navigation-guided percutaneous mediastinal biopsy is a safe procedure • Mediastinal vascular injury can be avoided under CBCT virtual navigation guidance.
OBJECTIVES: To assess the usefulness of C-arm cone-beam computed tomography (CBCT) virtual navigation-guided percutaneous mediastinal mass biopsy in terms of diagnostic accuracy and complication rates. METHODS: Seventy-eight CBCT virtual navigation-guided percutaneous mediastinal mass biopsies were performed in 75 patients (M:F, 38:37; mean age, 48.55 ± 18.76 years). The procedural details, diagnostic sensitivity, specificity, accuracy and complication rate were investigated. RESULTS: Mean lesion size was 6.80 ± 3.08 cm, skin-to-target distance was 3.67 ± 1.80 cm, core needle biopsy rate was 96.2 % (75/78), needle indwelling time was 9.29 ± 4.34 min, total procedure time was 13.26 ± 5.29 min, number of biopsy specimens obtained was 3.13 ± 1.02, number of CBCTs performed was 3.03 ± 0.68, rate of lesion border discrimination from abutting mediastinal structures on CBCT was 26.9 % (21/78), technical success rate was 100 % (78/78), estimated effective dose was 5.33 ± 4.99 mSv, and the dose area product was 12,723.68 ± 10,665.74 mGy⋅cm(2). Among the 78 biopsies, 69 were malignant, 7 were benign and 2 were indeterminate. Diagnostic sensitivity, specificity and accuracy for the diagnosis of malignancies were 97.1 % (67/69), 100 % (7/7) and 97.4 % (74/76), respectively, with a complication rate of 3.85 % (3/78), all of which were small pneumothoraces. CONCLUSIONS: CBCT virtual navigation-guided biopsy is a highly accurate and safe procedure for the evaluation of mediastinal lesions. KEY POINTS: • CBCT virtual navigation-guided percutaneous mediastinal biopsy is highly accurate • CBCT virtual navigation-guided percutaneous mediastinal biopsy is a safe procedure • Mediastinal vascular injury can be avoided under CBCT virtual navigation guidance.
Authors: W M H Busser; S J Braak; J J Fütterer; M J L van Strijen; Y L Hoogeveen; F de Lange; L J Schultze Kool Journal: Br J Radiol Date: 2013-08-02 Impact factor: 3.039
Authors: Stephanie K Carlson; Joel P Felmlee; Claire E Bender; Richard L Ehman; Kelly L Classic; Tanya L Hoskin; William S Harmsen; Houchun H Hu Journal: Radiology Date: 2005-11 Impact factor: 11.105
Authors: P L Zinzani; G Corneli; A Cancellieri; M Magagnoli; N Lacava; F Gherlinzoni; M Bendandi; P Albertini; G Baruzzi; S Tura; M Boaron Journal: Haematologica Date: 1999-07 Impact factor: 9.941
Authors: G Carrafiello; F Fontana; M Mangini; A M Ierardi; E Cotta; C Floridi; F Piacentino; C Fugazzola Journal: Radiol Med Date: 2012-02-10 Impact factor: 3.469
Authors: Jin Woo Choi; Chang Min Park; Jin Mo Goo; Yang-Kyun Park; Wonmo Sung; Hyun-Ju Lee; Sang Min Lee; Ji Young Ko; Mi-Suk Shim Journal: AJR Am J Roentgenol Date: 2012-09 Impact factor: 3.959
Authors: Hyungjin Kim; Kum Ju Chae; Soon Ho Yoon; Miso Kim; Bhumsuk Keam; Tae Min Kim; Dong-Wan Kim; Jin Mo Goo; Chang Min Park Journal: Eur Radiol Date: 2017-08-07 Impact factor: 5.315
Authors: Caroline Burgard; Robert Stahl; Giovanna Negrao de Figueiredo; Julien Dinkel; Thomas Liebig; Dania Cioni; Emanuele Neri; Christoph G Trumm Journal: Diagnostics (Basel) Date: 2021-04-26