Literature DB >> 25913470

A small molecule--DNA binding landscape.

Jonathan B Chaires1.   

Abstract

This brief account traces the development of a "competition dialysis" method used to characterize the structural and sequence selectivity of DNA binding compounds. The method was inspired by a simple "differential dialysis" method pioneered by Don Crothers to explore base-selective intercalator binding. Results from compiled competition dialysis studies provide a small-molecule DNA binding landscape that shows a rich diversity of interactions and molecular recognition.
© 2015 Wiley Periodicals, Inc.

Entities:  

Keywords:  DNA binding; Donald Crothers; dialysis; molecular recognition

Mesh：

Substances：

Year:  2015        PMID： 25913470      PMCID： PMC5705039          DOI： 10.1002/bip.22660

Source DB:  PubMed          Journal:  Biopolymers        ISSN： 0006-3525            Impact factor:   2.505


  33 in total

1.  Assembly of an antiparallel homo-adenine DNA duplex by small-molecule binding.

Authors:  Ozgül Persil; Catherine T Santai; Swapan S Jain; Nicholas V Hud
Journal:  J Am Chem Soc       Date:  2004-07-21       Impact factor: 15.419

Review 2.  Competition dialysis: an assay to measure the structural selectivity of drug-nucleic acid interactions.

Authors:  Jonathan B Chaires
Journal:  Curr Med Chem Anticancer Agents       Date:  2005-07

Review 3.  Competition dialysis: a method for the study of structural selective nucleic acid binding.

Authors:  Patricia A Ragazzon; Nichola C Garbett; Jonathan B Chaires
Journal:  Methods       Date:  2007-06       Impact factor: 3.608

Review 4.  Sequence-specific DNA minor groove binders. Design and synthesis of netropsin and distamycin analogues.

Authors:  C Bailly; J B Chaires
Journal:  Bioconjug Chem       Date:  1998 Sep-Oct       Impact factor: 4.774

5.  Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay.

Authors:  J L Mergny; L Lacroix; M P Teulade-Fichou; C Hounsou; L Guittat; M Hoarau; P B Arimondo; J P Vigneron; J M Lehn; J F Riou; T Garestier; C Hélène
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-13       Impact factor: 11.205

6.  Allosteric conversion of Z DNA to an intercalated right-handed conformation by daunomycin.

Authors:  J B Chaires
Journal:  J Biol Chem       Date:  1986-07-05       Impact factor: 5.157

7.  Theoretical aspects of DNA-protein interactions: co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice.

Authors:  J D McGhee; P H von Hippel
Journal:  J Mol Biol       Date:  1974-06-25       Impact factor: 5.469

8.  An octakis-intercalating molecule.

Authors:  M M Murr; M T Harting; V Guelev; J Ren; J B Chaires; B L Iverson
Journal:  Bioorg Med Chem       Date:  2001-05       Impact factor: 3.641

9.  Molecular recognition of nucleic acids: coralyne binds strongly to poly(A).

Authors:  Feifei Xing; Guangtao Song; Jinsong Ren; Jonathan B Chaires; Xiaogang Qu
Journal:  FEBS Lett       Date:  2005-09-12       Impact factor: 4.124

10.  Discovery of novel triple helical DNA intercalators by an integrated virtual and actual screening platform.

Authors:  Patrick A Holt; Patricia Ragazzon; Lucjan Strekowski; Jonathan B Chaires; John O Trent
Journal:  Nucleic Acids Res       Date:  2009-01-09       Impact factor: 16.971
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  3 in total

1.  A rapid fluorescent indicator displacement assay and principal component/cluster data analysis for determination of ligand-nucleic acid structural selectivity.

Authors:  Rafael Del Villar-Guerra; Robert D Gray; John O Trent; Jonathan B Chaires
Journal:  Nucleic Acids Res       Date:  2018-04-20       Impact factor: 16.971

2.  A modular design for minor groove binding and recognition of mixed base pair sequences of DNA.

Authors:  Pu Guo; Ananya Paul; Arvind Kumar; Narinder K Harika; Siming Wang; Abdelbasset A Farahat; David W Boykin; W David Wilson
Journal:  Chem Commun (Camb)       Date:  2017-09-07       Impact factor: 6.222

Review 3.  Structural modifications of berberine and their binding effects towards polymorphic deoxyribonucleic acid structures: A review.

Authors:  Lanlan Fu; Jiajia Mou; Yanru Deng; Xiaoliang Ren
Journal:  Front Pharmacol       Date:  2022-08-09       Impact factor: 5.988
  3 in total

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