Literature DB >> 16125177

Molecular recognition of nucleic acids: coralyne binds strongly to poly(A).

Feifei Xing1, Guangtao Song, Jinsong Ren, Jonathan B Chaires, Xiaogang Qu.   

Abstract

The small molecule coralyne was found to bind preferentially and strongly to single-stranded poly(A) with an apparent association constant (Ka) of (1.8+/-0.3) x 10(6)M(-1). Binding of coralyne to poly(A) is predominantly enthalpically driven with a stoichiometry of one coralyne per four adenine bases. Poly(A) forms a coralyne dependent secondary structure with a melting temperature of 60 degrees C, for the conditions of our study.

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Year:  2005        PMID： 16125177     DOI： 10.1016/j.febslet.2005.07.091

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  24 in total

1.  A tunable assay for modulators of genome-destabilizing DNA structures.

Authors:  Imee M A Del Mundo; Eun Jeong Cho; Kevin N Dalby; Karen M Vasquez
Journal:  Nucleic Acids Res       Date:  2019-07-26       Impact factor: 16.971

2.  Intercalation as a means to suppress cyclization and promote polymerization of base-pairing oligonucleotides in a prebiotic world.

Authors:  Eric D Horowitz; Aaron E Engelhart; Michael C Chen; Kaycee A Quarles; Michael W Smith; David G Lynn; Nicholas V Hud
Journal:  Proc Natl Acad Sci U S A       Date:  2010-03-08       Impact factor: 11.205

3.  Thermodynamics of nucleic acid "shape readout" by an aminosugar.

Authors:  Hongjuan Xi; Erik Davis; Nihar Ranjan; Liang Xue; David Hyde-Volpe; Dev P Arya
Journal:  Biochemistry       Date:  2011-10-03       Impact factor: 3.162

Review 4.  RNA targeting by small molecules: Binding of protoberberine, benzophenanthridine and aristolochia alkaloids to various RNA structures.

Authors:  Gopinatha Suresh Kumar
Journal:  J Biosci       Date:  2012-07       Impact factor: 1.826

5.  A small molecule--DNA binding landscape.

Authors:  Jonathan B Chaires
Journal:  Biopolymers       Date:  2015-09       Impact factor: 2.505

6.  Polymorphic nucleic Acid binding of bioactive isoquinoline alkaloids and their role in cancer.

Authors:  Motilal Maiti; Gopinatha Suresh Kumar
Journal:  J Nucleic Acids       Date:  2009-12-15

7.  A 'light-up' intercalator displacement assay for detection of triplex DNA stabilizers.

Authors:  Imee M A Del Mundo; Eun Jeong Cho; Kevin N Dalby; Karen M Vasquez
Journal:  Chem Commun (Camb)       Date:  2020-02-13       Impact factor: 6.222

8.  Molecular dynamics simulations and coupled nucleotide substitution experiments indicate the nature of A{middle dot}A base pairing and a putative structure of the coralyne-induced homo-adenine duplex.

Authors:  In Suk Joung; Ozgül Persil Cetinkol; Nicholas V Hud; Thomas E Cheatham
Journal:  Nucleic Acids Res       Date:  2009-12       Impact factor: 16.971

9.  New aspects of the interaction of the antibiotic coralyne with RNA: coralyne induces triple helix formation in poly(rA)*poly(rU).

Authors:  Tarita Biver; Alessia Boggioni; Begoña García; José M Leal; Rebeca Ruiz; Fernando Secco; Marcella Venturini
Journal:  Nucleic Acids Res       Date:  2009-12-14       Impact factor: 16.971

10.  Toward site-specific, homogeneous and highly stable fluorescent silver nanoclusters fabrication on triplex DNA scaffolds.

Authors:  Lingyan Feng; Zhenzhen Huang; Jinsong Ren; Xiaogang Qu
Journal:  Nucleic Acids Res       Date:  2012-05-08       Impact factor: 16.971
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