Bao-lin Li1, Wei Li1, Jia-Qi Bi1, Jian-gang Zhao1, Zhi-Wei Qu1, Chen Lin1, Song-Lin Yang2, Qing-gang Meng3, Qi Yue4. 1. Department of Orthopaedic Surgery, The First Hospital of Harbin City, Harbin Medical University, No. 149, Mai Mai Street, Dao Li District, 150001, Harbin, Heilongjiang Province, China. 2. Department of Surgery, Harbin Medical University, No. 23, You Zheng Street, Nan Gang District, 150001, Harbin, Heilongjiang Province, China. 3. Department of Orthopaedic Surgery, The First Hospital of Harbin City, Harbin Medical University, No. 149, Mai Mai Street, Dao Li District, 150001, Harbin, Heilongjiang Province, China. doctorbaolin@163.com. 4. Department of Surgery, Harbin Medical University, No. 23, You Zheng Street, Nan Gang District, 150001, Harbin, Heilongjiang Province, China. libaolin0609@163.com.
Abstract
BACKGROUND: In this report, the effects of long-term pulsed electromagnetic field (PEMF) exposure on hepatic and immunologic functions were examined. METHODS: Male rats were randomly divided into four groups: a control group and three experimental groups exposed to a 50-Hz PEMF at 5, 10, or 20 mT for 10 weeks. RESULTS: Compared with the control group, activities of serum alanine aminotransferase and aspartate aminotransferase and concentrations of serum, liver, and spleen Metabolism of lipid peroxidation (MDA) in the 10- and 20-mT PEMF groups were significantly increased. The activities of Glutathione peroxidase (GSH-Px) and Superoxide Dismutase (SOD) in the serum, liver, and spleen and concentrations of serum immunoglobulins were significantly decreased. CONCLUSION: These results demonstrate that long-term exposure to PEMF can lead to oxidative damage of the liver and spleen.
BACKGROUND: In this report, the effects of long-term pulsed electromagnetic field (PEMF) exposure on hepatic and immunologic functions were examined. METHODS: Male rats were randomly divided into four groups: a control group and three experimental groups exposed to a 50-Hz PEMF at 5, 10, or 20 mT for 10 weeks. RESULTS: Compared with the control group, activities of serum alanine aminotransferase and aspartate aminotransferase and concentrations of serum, liver, and spleen Metabolism of lipid peroxidation (MDA) in the 10- and 20-mT PEMF groups were significantly increased. The activities of Glutathione peroxidase (GSH-Px) and Superoxide Dismutase (SOD) in the serum, liver, and spleen and concentrations of serum immunoglobulins were significantly decreased. CONCLUSION: These results demonstrate that long-term exposure to PEMF can lead to oxidative damage of the liver and spleen.
Authors: Michelle A Sandrey; David N Vesper; Mary T Johnson; Gabi Nindl; John A Swez; Jack Chamberlain; Walter X Balcavage Journal: Bioelectromagnetics Date: 2002-01 Impact factor: 2.010