Literature DB >> 25905626

Analog electro-optical readout of SiPMs achieves fast timing required for time-of-flight PET/MR.

M F Bieniosek1, C S Levin.   

Abstract

The design of combined positron emission tomography/magnetic resonance (PET/MR) systems presents a number of challenges to engineers, as it forces the PET system to acquire data in a space constrained environment that is sensitive to electro-magnetic interference and contains high static, radio frequency and gradient fields. In this work we validate fast timing performance of a PET scintillation detector using a potentially very compact, very low power, and MR compatible readout method in which analog silicon photomultipliers (SiPM) signals are transmitted optically away from the MR bore with little or even no additional readout electronics. This analog 'electro-optial' method could reduce the entire PET readout in the MR bore to two compact, low power components (SiPMs and lasers). Our experiments show fast timing performance from analog electro-optical readout with and without pre-amplification. With 3 mm × 3 mm × 20 mm lutetium-yttrium oxyorthosilicate (LYSO) crystals and Excelitas SiPMs the best two-sided fwhm coincident timing resolution achieved was 220 +/- 3 ps in electrical mode, 230 +/- 2 ps in electro-optical with preamp mode, and 253 +/- 2 ps in electro-optical without preamp mode. Timing measurements were also performed with Hamamatsu SiPMs and 3 mm × 3 mm × 5 mm crystals. In the future the timing degradation seen can be further reduced with lower laser noise or improvements SiPM rise time or gain.

Entities:  

Mesh:

Substances:

Year:  2015        PMID: 25905626      PMCID: PMC4431650          DOI: 10.1088/0031-9155/60/9/3795

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  7 in total

1.  Performance test of an LSO-APD detector in a 7-T MRI scanner for simultaneous PET/MRI.

Authors:  Bernd J Pichler; Martin S Judenhofer; Ciprian Catana; Jeffrey H Walton; Manfred Kneilling; Robert E Nutt; Stefan B Siegel; Claus D Claussen; Simon R Cherry
Journal:  J Nucl Med       Date:  2006-04       Impact factor: 10.057

Review 2.  Pre-clinical PET/MR: technological advances and new perspectives in biomedical research.

Authors:  Hans F Wehrl; Martin S Judenhofer; Stefan Wiehr; Bernd J Pichler
Journal:  Eur J Nucl Med Mol Imaging       Date:  2009-03       Impact factor: 9.236

3.  Novel electro-optical coupling technique for magnetic resonance-compatible positron emission tomography detectors.

Authors:  Peter D Olcott; Hao Peng; Craig S Levin
Journal:  Mol Imaging       Date:  2009 Mar-Apr       Impact factor: 4.488

4.  20-Gbit/s directly modulated photonic crystal nanocavity laser with ultra-low power consumption.

Authors:  Shinji Matsuo; Akihiko Shinya; Chin-Hui Chen; Kengo Nozaki; Tomonari Sato; Yoshihiro Kawaguchi; Hideaki Taniyama; Masaya Notomi
Journal:  Opt Express       Date:  2011-01-31       Impact factor: 3.894

5.  Simultaneous PET and MR imaging.

Authors:  Y Shao; S R Cherry; K Farahani; K Meadors; S Siegel; R W Silverman; P K Marsden
Journal:  Phys Med Biol       Date:  1997-10       Impact factor: 3.609

6.  A prototype MR insertable brain PET using tileable GAPD arrays.

Authors:  Key Jo Hong; Yong Choi; Jin Ho Jung; Jihoon Kang; Wei Hu; Hyun Keong Lim; Yoonsuk Huh; Sangsu Kim; Ji Woong Jung; Kyu Bom Kim; Myung Sung Song; Hyun-Wook Park
Journal:  Med Phys       Date:  2013-04       Impact factor: 4.071

7.  Readout strategy of an electro-optical coupled PET detector for time-of-flight PET/MRI.

Authors:  M F Bieniosek; P D Olcott; C S Levin
Journal:  Phys Med Biol       Date:  2013-09-24       Impact factor: 3.609

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.