Literature DB >> 25891472

Antibiotic loaded nanocapsules functionalized with aptamer gates for targeted destruction of pathogens.

M Kavruk1, O Celikbicak, V C Ozalp, B A Borsa, F J Hernandez, G Bayramoglu, B Salih, M Y Arica.   

Abstract

In this study, we designed aptamer-gated nanocapsules for the specific targeting of cargo to bacteria with controlled release of antibiotics based on aptamer-receptor interactions. Aptamer-gates caused a specific decrease in minimum inhibitory concentration (MIC) values of vancomycin for Staphylococcus aureus when mesoporous silica nanoparticles (MSNs) were used for bacteria-targeted delivery.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 25891472     DOI： 10.1039/c5cc01869b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  18 in total

Review 1.  Programmable biomaterials for dynamic and responsive drug delivery.

Authors:  Anna Stejskalová; Mehrdad T Kiani; Benjamin D Almquist
Journal:  Exp Biol Med (Maywood)       Date:  2016-05-13

Review 2.  Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

Authors:  María Vallet-Regí; Ferdi Schüth; Daniel Lozano; Montserrat Colilla; Miguel Manzano
Journal:  Chem Soc Rev       Date:  2022-07-04       Impact factor: 60.615

Review 3.  Nanomaterial-based fluorescent biosensors for veterinary drug detection in foods.

Authors:  Xiaoqi Tao; Yuanyuan Peng; Juewen Liu
Journal:  J Food Drug Anal       Date:  2020-12-15       Impact factor: 6.157

4.  Aptamer-Targeted Drug Delivery for Staphylococcus aureus Biofilm.

Authors:  Pernille Ommen; Line Hansen; Bente K Hansen; Hieu Vu-Quang; Jørgen Kjems; Rikke L Meyer
Journal:  Front Cell Infect Microbiol       Date:  2022-04-29       Impact factor: 6.073

5.  Inhibitory effects of aptamer targeted teicoplanin encapsulated PLGA nanoparticles for Staphylococcus aureus strains.

Authors:  Samet Ucak; Mert Sudagidan; Baris A Borsa; Banu Mansuroglu; Veli C Ozalp
Journal:  World J Microbiol Biotechnol       Date:  2020-04-25       Impact factor: 3.312

Review 6.  Aptamer Hybrid Nanocomplexes as Targeting Components for Antibiotic/Gene Delivery Systems and Diagnostics: A Review.

Authors:  Navid Rabiee; Sepideh Ahmadi; Zeynab Arab; Mojtaba Bagherzadeh; Moein Safarkhani; Behzad Nasseri; Mohammad Rabiee; Mohammadreza Tahriri; Thomas J Webster; Lobat Tayebi
Journal:  Int J Nanomedicine       Date:  2020-06-17

7.  Vancomycin-Loaded Nanoparticles Enhance Sporicidal and Antibacterial Efficacy for Clostridium difficile Infection.

Authors:  Yi-Hsuan Chen; Tsung-Ju Li; Bo-Yang Tsai; Liang-Kuei Chen; Yi-Hsin Lai; Meng-Jia Li; Cheng-Yang Tsai; Pei-Jane Tsai; Dar-Bin Shieh
Journal:  Front Microbiol       Date:  2019-05-24       Impact factor: 5.640

8.  Antibiotic administration in targeted nanoparticles protects the faecal microbiota of mice.

Authors:  Baris A Borsa; Mert Sudagidan; Mehmet E Aldag; Isik I Baris; Elif E Acar; Cagatay Acuner; Murat Kavruk; Veli C Ozalp
Journal:  RSC Med Chem       Date:  2021-01-15

Review 9.  Oligonucleotide aptamers: promising and powerful diagnostic and therapeutic tools for infectious diseases.

Authors:  Qin Pan; Fengling Luo; Min Liu; Xiao-Lian Zhang
Journal:  J Infect       Date:  2018-05-07       Impact factor: 6.072

Review 10.  Therapeutic applications of nucleic acid aptamers in microbial infections.

Authors:  Shima Afrasiabi; Maryam Pourhajibagher; Reza Raoofian; Maryam Tabarzad; Abbas Bahador
Journal:  J Biomed Sci       Date:  2020-01-03       Impact factor: 8.410
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.