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Literature DB >> 27190245

Programmable biomaterials for dynamic and responsive drug delivery.

Anna Stejskalová¹, Mehrdad T Kiani¹, Benjamin D Almquist².

Abstract

Biomaterials are continually being designed that enable new methods for interacting dynamically with cell and tissues, in turn unlocking new capabilities in areas ranging from drug delivery to regenerative medicine. In this review, we explore some of the recent advances being made in regards to programming biomaterials for improved drug delivery, with a focus on cancer and infection. We begin by explaining several of the underlying concepts that are being used to design this new wave of drug delivery vehicles, followed by examining recent materials systems that are able to coordinate the temporal delivery of multiple therapeutics, dynamically respond to changing tissue environments, and reprogram their bioactivity over time.

Entities: Disease

Keywords: Bionanoscience; bacteria; biomaterials; cancer; drug delivery; nanoparticles

Mesh：

Substances：

Year: 2016 PMID： 27190245 PMCID： PMC4950367 DOI： 10.1177/1535370216649445

Source DB: PubMed Journal: Exp Biol Med (Maywood) ISSN： 1535-3699

98 in total

Review 1. Current applications of nanoparticles in infectious diseases.

Authors: Hinojal Zazo; Clara I Colino; José M Lanao
Journal: J Control Release Date: 2016-01-06 Impact factor: 9.776

Review 2. Cu-catalyzed azide-alkyne cycloaddition.

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Journal: Chem Rev Date: 2008-08 Impact factor: 60.622

3. Mimicking biological phenomena in hydrogel-based biomaterials to promote dynamic cellular responses.

Authors: Nicholas P Murphy; Kyle J Lampe
Journal: J Mater Chem B Date: 2015-09-14 Impact factor: 6.331

4. Poly(L-lysine) Interfaces via Dual Click Reactions on Surface-Bound Custom-Designed Dithiol Adsorbates.

Authors: Amin Shakiba; Andrew C Jamison; T Randall Lee
Journal: Langmuir Date: 2015-05-26 Impact factor: 3.882

5. Implantable hydrogel embedded dark-gold nanoswitch as a theranostic probe to sense and overcome cancer multidrug resistance.

Authors: João Conde; Nuria Oliva; Natalie Artzi
Journal: Proc Natl Acad Sci U S A Date: 2015-03-02 Impact factor: 11.205

Review 6. Multidrug resistance in bacteria.

Authors: Hiroshi Nikaido
Journal: Annu Rev Biochem Date: 2009 Impact factor: 23.643

Programmable biomaterials for dynamic and responsive drug delivery.

Review 1. Current applications of nanoparticles in infectious diseases.

Review 2. Cu-catalyzed azide-alkyne cycloaddition.

3. Mimicking biological phenomena in hydrogel-based biomaterials to promote dynamic cellular responses.

4. Poly(L-lysine) Interfaces via Dual Click Reactions on Surface-Bound Custom-Designed Dithiol Adsorbates.

5. Implantable hydrogel embedded dark-gold nanoswitch as a theranostic probe to sense and overcome cancer multidrug resistance.

Review 6. Multidrug resistance in bacteria.

7. Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay.

Review 8. Engineered in-situ depot-forming hydrogels for intratumoral drug delivery.

9. Nanoparticles that communicate in vivo to amplify tumour targeting.

10. Infection-mimicking materials to program dendritic cells in situ.

Review 1. Design strategies for physical-stimuli-responsive programmable nanotherapeutics.

2. Design strategies for programmable oligonucleotide nanotherapeutics.

Review 3. Using biomaterials to rewire the process of wound repair.