| Literature DB >> 25882557 |
Dimitar V Zlatev1, Emanuela Altobelli2, Joseph C Liao3.
Abstract
Bladder cancer ranges from a low-grade variant to high-grade disease. Assessment for treatment depends on white light cystoscopy, however because of its limitations there is a need for improved visualization of flat, multifocal, high-grade, and muscle-invasive lesions. Photodynamic diagnosis and narrow-band imaging provide additional contrast enhancement of bladder tumors and have been shown to improve detection rates. Confocal laser endomicroscopy and optical coherence tomography enable real-time, high-resolution, subsurface tissue characterization with spatial resolutions similar to histology. Molecular imaging offers the potential for the combination of optical imaging technologies with cancer-specific molecular agents to improve the specificity of disease detection. Published by Elsevier Inc.Entities:
Keywords: Bladder cancer; Confocal laser endomicroscopy; Fluorescence cystoscopy; Molecular imaging; Narrow band imaging; Optical coherence tomography; Photodynamic diagnosis
Mesh:
Year: 2015 PMID: 25882557 PMCID: PMC4402158 DOI: 10.1016/j.ucl.2015.01.001
Source DB: PubMed Journal: Urol Clin North Am ISSN: 0094-0143 Impact factor: 2.241