Literature DB >> 25877186

Cancer: The Ras renaissance.

Heidi Ledford.   

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Year:  2015        PMID： 25877186     DOI： 10.1038/520278a

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  5 in total

Review 1.  Development of farnesyl transferase inhibitors: a review.

Authors:  Natalie M G M Appels; Jos H Beijnen; Jan H M Schellens
Journal:  Oncologist       Date:  2005-09

Review 2.  Synthetic lethal vulnerabilities of cancer.

Authors:  Ferran Fece de la Cruz; Bianca V Gapp; Sebastian M B Nijman
Journal:  Annu Rev Pharmacol Toxicol       Date:  2014-10-09       Impact factor: 13.820

3.  Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses.

Authors:  C J Der; T G Krontiris; G M Cooper
Journal:  Proc Natl Acad Sci U S A       Date:  1982-06       Impact factor: 11.205

4.  K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.

Authors:  Jonathan M Ostrem; Ulf Peters; Martin L Sos; James A Wells; Kevan M Shokat
Journal:  Nature       Date:  2013-11-20       Impact factor: 49.962

5.  Discovery of small molecules that bind to K-Ras and inhibit Sos-mediated activation.

Authors:  Qi Sun; Jason P Burke; Jason Phan; Michael C Burns; Edward T Olejniczak; Alex G Waterson; Taekyu Lee; Olivia W Rossanese; Stephen W Fesik
Journal:  Angew Chem Int Ed Engl       Date:  2012-05-08       Impact factor: 15.336
  5 in total
  50 in total

Review 1.  How to Target Activated Ras Proteins: Direct Inhibition vs. Induced Mislocalization.

Authors:  Ethan J Brock; Kyungmin Ji; John J Reiners; Raymond R Mattingly
Journal:  Mini Rev Med Chem       Date:  2016       Impact factor: 3.862

Review 2.  Drugging Ras GTPase: a comprehensive mechanistic and signaling structural view.

Authors:  Shaoyong Lu; Hyunbum Jang; Shuo Gu; Jian Zhang; Ruth Nussinov
Journal:  Chem Soc Rev       Date:  2016-07-11       Impact factor: 54.564

Review 3.  Ras and Rap1: A tale of two GTPases.

Authors:  Seema Shah; Ethan J Brock; Kyungmin Ji; Raymond R Mattingly
Journal:  Semin Cancer Biol       Date:  2018-04-03       Impact factor: 15.707

4.  Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies.

Authors:  Andrew M Waters; Irem Ozkan-Dagliyan; Angelina V Vaseva; Nicole Fer; Leslie A Strathern; G Aaron Hobbs; Basile Tessier-Cloutier; William K Gillette; Rachel Bagni; Gordon R Whiteley; James L Hartley; Frank McCormick; Adrienne D Cox; Peter J Houghton; David G Huntsman; Mark R Philips; Channing J Der
Journal:  Sci Signal       Date:  2017-09-26       Impact factor: 8.192

Review 5.  Inhibition of Nonfunctional Ras.

Authors:  Ruth Nussinov; Hyunbum Jang; Attila Gursoy; Ozlem Keskin; Vadim Gaponenko
Journal:  Cell Chem Biol       Date:  2021-01-12       Impact factor: 8.116

Review 6.  Targeting Ras with Macromolecules.

Authors:  Dehua Pei; Kuangyu Chen; Hui Liao
Journal:  Cold Spring Harb Perspect Med       Date:  2018-03-01       Impact factor: 6.915

Review 7.  Genomic alterations in pancreatic cancer and their relevance to therapy.

Authors:  Erina Takai; Shinichi Yachida
Journal:  World J Gastrointest Oncol       Date:  2015-10-15

Review 8.  CRISPR/Cas9 library screening for drug target discovery.

Authors:  Morito Kurata; Kouhei Yamamoto; Branden S Moriarity; Masanobu Kitagawa; David A Largaespada
Journal:  J Hum Genet       Date:  2017-11-20       Impact factor: 3.172

Review 9.  RAS isoforms and mutations in cancer at a glance.

Authors:  G Aaron Hobbs; Channing J Der; Kent L Rossman
Journal:  J Cell Sci       Date:  2016-03-16       Impact factor: 5.285

10.  MicroRNA-30a attenuates mutant KRAS-driven colorectal tumorigenesis via direct suppression of ME1.

Authors:  Hongxing Shen; Chuan Xing; Kaisa Cui; Yunxiao Li; Jinxiang Zhang; Runlei Du; Xiaodong Zhang; Youjun Li
Journal:  Cell Death Differ       Date:  2017-05-05       Impact factor: 15.828
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