Literature DB >> 2587261

Structure and functional expression of a cloned Xenopus thyroid hormone receptor.

A R Brooks1, G Sweeney, R W Old.   

Abstract

A clone corresponding to a thyroid hormone receptor was isolated from a Xenopus laevis cDNA library prepared from folliculated oocytes. The cDNA encodes a protein of 418 amino acid residues with a domain structure, including a putative DNA binding region with two zinc fingers, similar to other members of the v-erbA-related superfamily of receptors. The encoded protein resembles the TR alpha 1-type receptor of the rat. When expressed in COS cells the protein product binds triiodothyronine with a Kd of 0.12 nM. The receptor mediates thyroid-hormone-inducible expression of a reporter gene which includes a thyroid hormone response element in its upstream region.

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Year:  1989        PMID： 2587261      PMCID： PMC335140          DOI： 10.1093/nar/17.22.9395

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  18 in total

1.  On the fidelity of mRNA translation in the nuclease-treated rabbit reticulocyte lysate system.

Authors:  M C Dasso; R J Jackson
Journal:  Nucleic Acids Res       Date:  1989-04-25       Impact factor: 16.971

2.  Early metamorphic competence of Xenopus larvae.

Authors:  J R Tata
Journal:  Dev Biol       Date:  1968-11       Impact factor: 3.582

3.  The c-erb-A protein is a high-affinity receptor for thyroid hormone.

Authors:  J Sap; A Muñoz; K Damm; Y Goldberg; J Ghysdael; A Leutz; H Beug; B Vennström
Journal:  Nature       Date:  1986 Dec 18-31       Impact factor: 49.962

Review 4.  Zinc fingers: gilt by association.

Authors:  R M Evans; S M Hollenberg
Journal:  Cell       Date:  1988-01-15       Impact factor: 41.582

5.  Short-term, high-efficiency expression of transfected DNA.

Authors:  D J Sussman; G Milman
Journal:  Mol Cell Biol       Date:  1984-08       Impact factor: 4.272

6.  Rapid and efficient site-specific mutagenesis without phenotypic selection.

Authors:  T A Kunkel
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205

7.  Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system.

Authors:  C C Thompson; C Weinberger; R Lebo; R M Evans
Journal:  Science       Date:  1987-09-25       Impact factor: 47.728

8.  Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

Authors:  C M Gorman; L F Moffat; B H Howard
Journal:  Mol Cell Biol       Date:  1982-09       Impact factor: 4.272

9.  Filter-binding assay procedure for thyroid hormone receptors.

Authors:  A Inoue; J Yamakawa; M Yukioka; S Morisawa
Journal:  Anal Biochem       Date:  1983-10-01       Impact factor: 3.365

Review 10.  The steroid and thyroid hormone receptor superfamily.

Authors:  R M Evans
Journal:  Science       Date:  1988-05-13       Impact factor: 47.728
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  11 in total

1.  Thyroid hormone receptor transcriptional activity is potentially autoregulated by truncated forms of the receptor.

Authors:  J Bigler; W Hokanson; R N Eisenman
Journal:  Mol Cell Biol       Date:  1992-05       Impact factor: 4.272

Review 2.  Amphibian metamorphosis.

Authors:  Donald D Brown; Liquan Cai
Journal:  Dev Biol       Date:  2007-03-23       Impact factor: 3.582

3.  Xenopus laevis alpha and beta thyroid hormone receptors.

Authors:  Y Yaoita; Y B Shi; D D Brown
Journal:  Proc Natl Acad Sci U S A       Date:  1990-09       Impact factor: 11.205

4.  Precocious synthesis of a thyroid hormone receptor inXenopus embryos causes hormone-dependent developmental abnormalities.

Authors:  Robert Old; Elizabeth Ashby Jones; Glen Sweeney; Darrin Paul Smith
Journal:  Rouxs Arch Dev Biol       Date:  1992-09

5.  Expression of a dominant negative retinoic acid receptor γ in Xenopus embryos leads to partial resistance to retinoic acid.

Authors:  Darrin Paul Smith; Clive Scott Mason; Elizabeth Jones; Robert Old
Journal:  Rouxs Arch Dev Biol       Date:  1994-03

6.  Accumulation of proto-oncogene c-erb-A related transcripts during Xenopus development: association with early acquisition of response to thyroid hormone and estrogen.

Authors:  B S Baker; J R Tata
Journal:  EMBO J       Date:  1990-03       Impact factor: 11.598

7.  The thyroid hormone receptor gene (c-erbA alpha) is expressed in advance of thyroid gland maturation during the early embryonic development of Xenopus laevis.

Authors:  D E Banker; J Bigler; R N Eisenman
Journal:  Mol Cell Biol       Date:  1991-10       Impact factor: 4.272

8.  A novel nuclear receptor superfamily member in Xenopus that associates with RXR, and shares extensive sequence similarity to the mammalian vitamin D3 receptor.

Authors:  D P Smith; C S Mason; E A Jones; R W Old
Journal:  Nucleic Acids Res       Date:  1994-01-11       Impact factor: 16.971

9.  Mouse retinoid X receptor contains a separable ligand-binding and transactivation domain in its E region.

Authors:  X Leng; J Blanco; S Y Tsai; K Ozato; B W O'Malley; M J Tsai
Journal:  Mol Cell Biol       Date:  1995-01       Impact factor: 4.272

10.  Chimeric retinoic acid/thyroid hormone receptors implicate RAR-alpha 1 as mediating growth inhibition by retinoic acid.

Authors:  J G Schilthuis; A A Gann; J P Brockes
Journal:  EMBO J       Date:  1993-09       Impact factor: 11.598
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