Literature DB >> 3629259

Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system.

C C Thompson, C Weinberger, R Lebo, R M Evans.   

Abstract

A complementary DNA clone derived from rat brain messenger RNA has been isolated on the basis of homology to the human thyroid hormone receptor gene. Expression of this complementary DNA produces a high-affinity binding protein for thyroid hormones. Sequence analysis and the mapping of this gene to a distinct human genetic locus indicate the existence of multiple human thyroid hormone receptors. Messenger RNA from this gene is expressed in a tissue-specific fashion with highest levels in the central nervous system.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3629259     DOI： 10.1126/science.3629259

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  75 in total

1.  Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor.

Authors:  Sabine Borngraeber; Mary-Jane Budny; Grazia Chiellini; Suzana T Cunha-Lima; Marie Togashi; Paul Webb; John D Baxter; Thomas S Scanlan; Robert J Fletterick
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-12       Impact factor: 11.205

2.  Accumulation of different c-erbA transcripts during rat brain development and in cortical neurons cultured in a synthetic medium.

Authors:  D Castiglia; A Cestelli; C Di Liegro; L Bonfanti; I Di Liegro
Journal:  Cell Mol Neurobiol       Date:  1992-06       Impact factor: 5.046

Review 3.  Neuronal cell cultures: a tool for investigations in developmental neurobiology.

Authors:  A Cestelli; G Savettieri; G Salemi; I Di Liegro
Journal:  Neurochem Res       Date:  1992-12       Impact factor: 3.996

4.  Thyroid hormone receptor transcriptional activity is potentially autoregulated by truncated forms of the receptor.

Authors:  J Bigler; W Hokanson; R N Eisenman
Journal:  Mol Cell Biol       Date:  1992-05       Impact factor: 4.272

Review 5.  Nuclear thyroid hormone receptors.

Authors:  M A Lazar; W W Chin
Journal:  J Clin Invest       Date:  1990-12       Impact factor: 14.808

6.  The C'-terminal interaction domain of the thyroid hormone receptor confers the ability of the DNA site to dictate positive or negative transcriptional activity.

Authors:  J M Holloway; C K Glass; S Adler; C A Nelson; M G Rosenfeld
Journal:  Proc Natl Acad Sci U S A       Date:  1990-10       Impact factor: 11.205

Review 7.  Molecular basis of cardiac performance. Plasticity of the myocardium generated through protein isoform switches.

Authors:  B Nadal-Ginard; V Mahdavi
Journal:  J Clin Invest       Date:  1989-12       Impact factor: 14.808

8.  Is the thyroid still important in major depression?

Authors:  Russell T Joffe
Journal:  J Psychiatry Neurosci       Date:  2006-11       Impact factor: 6.186

9.  Human carboxyl-terminal variant of alpha-type c-erbA inhibits trans-activation by thyroid hormone receptors without binding thyroid hormone.

Authors:  M A Lazar; R A Hodin; W W Chin
Journal:  Proc Natl Acad Sci U S A       Date:  1989-10       Impact factor: 11.205

10.  Alpha and beta thyroid hormone receptor (TR) gene expression during auditory neurogenesis: evidence for TR isoform-specific transcriptional regulation in vivo.

Authors:  D J Bradley; H C Towle; W S Young
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-18       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.