B J S al-Haddad1, Elima Jedy-Agba2, Emmanuel Oga3, E R Ezeome4, Christopher C Obiorah5, Michael Okobia6, J Olufemi Ogunbiyi7, Cornelius Ozobia Ukah8, Abidemi Omonisi9, A M E Nwofor10, Festus Igbinoba11, Clement Adebamowo12. 1. Medical Scientist Training Program, University of Minnesota, 420 Delaware Street SE, B681 Mayo Building, MMC 293, Minneapolis, MN 55414, USA. Electronic address: haddad@umn.edu. 2. Institute of Human Virology, Nigeria, Pent House, Maina Court, Plot 252, Herbert Macaulay Way, Central Business District, P.O. Box 9396, Garki, Abuja, Nigeria. Electronic address: elima.jedyagba@gmail.com. 3. Institute of Human Virology, Nigeria, Pent House, Maina Court, Plot 252, Herbert Macaulay Way, Central Business District, P.O. Box 9396, Garki, Abuja, Nigeria. Electronic address: imanueloga@gmail.com. 4. University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Enugu State, Nigeria. Electronic address: ezeome95@gmail.com. 5. University of Port Harcourt Teaching Hospital, East-West Road, Port Harcourt, Rivers State, Nigeria. Electronic address: christopherobiorah@yahoo.com. 6. Professor Olikoye Ransome-Kuti (Midwestern Nigeria) Cancer Registry, Department of Surgery, University of Benin Teaching Hospital, P.M.B. 1111, Benin City, Edo State, Nigeria. Electronic address: michaelokobia@yahoo.com. 7. Ibadan Cancer Registry, Department of Pathology, University College Hospital, P.M.B. 5116, Ibadan, Nigeria. Electronic address: f_ogunbiyi@yahoo.com. 8. Nnewi Cancer Registry, Nnamdi Azikiwe University Teaching Hospital, P.M.B. 5025, Nnewi, Anambra State, Nigeria. Electronic address: ukahcornelius@yahoo.com. 9. Ife Ijesha Cancer Registry, Obafemi Awolowo University Teaching Hospitals, PO Box 1923, Ile Ife, Osun State, Nigeria. Electronic address: abidemi.omonisi@gmail.com. 10. Nnewi Cancer Registry, Nnamdi Azikiwe University Teaching Hospital, P.M.B. 5025, Nnewi, Anambra State, Nigeria. Electronic address: xnwofor@yahoo.com. 11. Abuja Cancer Registry, National Hospital, Abuja, Plot 132, Central District (Phase 11), P.M.B. 425, Garki-Abuja, Federal Capital Territory, Nigeria. Electronic address: figbinoba@gmail.com. 12. Institute of Human Virology, Nigeria, Pent House, Maina Court, Plot 252, Herbert Macaulay Way, Central Business District, P.O. Box 9396, Garki, Abuja, Nigeria. Electronic address: cadebamowo@yahoo.com.
Abstract
BACKGROUND: Like many countries in Africa, Nigeria is improving the quality and coverage of its cancer surveillance. This work is essential to address this growing category of chronic diseases, but is made difficult by economic, geographic and other challenges. PURPOSE: To evaluate the completeness, comparability and diagnostic validity of Nigeria's cancer registries. METHODS: Completeness was measured using children's age-specific incidence (ASI) and an established metric based on a modified Poisson distribution with regional comparisons. We used a registry questionnaire as well as percentages of death-certificate-only cases, morphologically verified cases, and case registration errors to examine comparability and diagnostic validity. RESULTS: Among the children's results, we found that over half of all cancers were non-Hodgkin lymphoma. There was also evidence of incompleteness. Considering the regional completeness comparisons, we found potential evidence of cancer-specific general incompleteness as well as what appears to be incompleteness due to inability to diagnose specific cancers. We found that registration was generally comparable, with some exceptions. Since autopsies are not common across Nigeria, coding for both them and death-certificate-only cases was also rare. With one exception, registries in our study had high rates of morphological verification of female breast, cervical and prostate cancers. CONCLUSIONS: Nigeria's registration procedures were generally comparable to each other and to international standards, and we found high rates of morphological verification, suggesting high diagnostic validity. There was, however, evidence of incompleteness.
BACKGROUND: Like many countries in Africa, Nigeria is improving the quality and coverage of its cancer surveillance. This work is essential to address this growing category of chronic diseases, but is made difficult by economic, geographic and other challenges. PURPOSE: To evaluate the completeness, comparability and diagnostic validity of Nigeria's cancer registries. METHODS: Completeness was measured using children's age-specific incidence (ASI) and an established metric based on a modified Poisson distribution with regional comparisons. We used a registry questionnaire as well as percentages of death-certificate-only cases, morphologically verified cases, and case registration errors to examine comparability and diagnostic validity. RESULTS: Among the children's results, we found that over half of all cancers were non-Hodgkin lymphoma. There was also evidence of incompleteness. Considering the regional completeness comparisons, we found potential evidence of cancer-specific general incompleteness as well as what appears to be incompleteness due to inability to diagnose specific cancers. We found that registration was generally comparable, with some exceptions. Since autopsies are not common across Nigeria, coding for both them and death-certificate-only cases was also rare. With one exception, registries in our study had high rates of morphological verification of female breast, cervical and prostate cancers. CONCLUSIONS: Nigeria's registration procedures were generally comparable to each other and to international standards, and we found high rates of morphological verification, suggesting high diagnostic validity. There was, however, evidence of incompleteness.
Authors: Leah L Zullig; Kristin Schroeder; Pilli Nyindo; Theresia Namwai; Elvis Silayo; Angelah Msomba; Michael Oresto Munishi; Francis Karia; Charles Muiruri; John Bartlett; Venance Maro; S Yousuf Zafar Journal: J Glob Oncol Date: 2016-04-27
Authors: Elima E Jedy-Agba; Emmanuel A Oga; Michael Odutola; Yusuf M Abdullahi; Abiodun Popoola; Peter Achara; Enoch Afolayan; Adekunbiola Aina Fehintola Banjo; Ima-Obong Ekanem; Olagoke Erinomo; Emmanuel Ezeome; Festus Igbinoba; Christopher Obiorah; Olufemi Ogunbiyi; Abidemi Omonisi; Clement Osime; Cornelius Ukah; Patience Osinubi; Ramatu Hassan; William Blattner; Patrick Dakum; Clement A Adebamowo Journal: Front Public Health Date: 2015-07-30
Authors: Davies Adeloye; Olaperi Y Sowunmi; Wura Jacobs; Rotimi A David; Adeyemi A Adeosun; Ann O Amuta; Sanjay Misra; Muktar Gadanya; Asa Auta; Michael O Harhay; Kit Yee Chan Journal: J Glob Health Date: 2018-06 Impact factor: 4.413