OBJECTIVE: To investigate the relationship between Vitamin D deficiency and acute otitis media infection. METHODS: The randomised, single-blind, case-control study was conducted at the Paediatric Department of Ataturk University, Erzurum, Turkey, from January to April 2010. It comprised ambulatory children diagnosed with acute otitis media and healthy controls. The subjects were divided into groups according to their serum 25-hydroxy vitamin D levels. SPSS 18 was used for statistical analysis. RESULTS: Of the 169 subjects in the study, 88(52%) were the cases and 81(48%) were controls. The mean age of the cases was 6.21±3.4 years, and 6.18±3.12 years for the controls (p<0.951). Serum 25-hydroxy vitamin D levels in the cases and controls were 20.6±10.2 ng/mL and 23.8±10.3 ng/mL (p<0.05). There was no statistically significant difference between the groups in terms of parathormone and calcium levels (p>0.05). CONCLUSION:Serum 25-hydroxy vitamin D levels being significantly lower in children diagnosed with acute otitis media compared to the controls in two otherwise similar groups suggests that Vitamin D deficiency plays a role in otitis media infection.
RCT Entities:
OBJECTIVE: To investigate the relationship between Vitamin Ddeficiency and acute otitis media infection. METHODS: The randomised, single-blind, case-control study was conducted at the Paediatric Department of Ataturk University, Erzurum, Turkey, from January to April 2010. It comprised ambulatory children diagnosed with acute otitis media and healthy controls. The subjects were divided into groups according to their serum 25-hydroxy vitamin D levels. SPSS 18 was used for statistical analysis. RESULTS: Of the 169 subjects in the study, 88(52%) were the cases and 81(48%) were controls. The mean age of the cases was 6.21±3.4 years, and 6.18±3.12 years for the controls (p<0.951). Serum 25-hydroxy vitamin D levels in the cases and controls were 20.6±10.2 ng/mL and 23.8±10.3 ng/mL (p<0.05). There was no statistically significant difference between the groups in terms of parathormone and calcium levels (p>0.05). CONCLUSION: Serum 25-hydroxy vitamin D levels being significantly lower in children diagnosed with acute otitis media compared to the controls in two otherwise similar groups suggests that Vitamin D deficiency plays a role in otitis media infection.
Authors: Fatih Alper Akcan; Yusuf Dündar; Hümeyra Bayram Akcan; Ahmet Uluat; Derya Cebeci; İlhan Ünlü Journal: Eur Arch Otorhinolaryngol Date: 2019-01-14 Impact factor: 2.503
Authors: Wojciech Feleszko; Ricardo Marengo; Antonio Sousa Vieira; Karol Ratajczak; José Luis Mayorga Butrón Journal: Clin Otolaryngol Date: 2019-04-14 Impact factor: 2.597
Authors: Elena Chiappini; Francesca Santamaria; Gian Luigi Marseglia; Paola Marchisio; Luisa Galli; Renato Cutrera; Maurizio de Martino; Sara Antonini; Paolo Becherucci; Paolo Biasci; Barbara Bortone; Sergio Bottero; Valeria Caldarelli; Fabio Cardinale; Guido Castelli Gattinara; Martina Ciarcià; Daniele Ciofi; Sofia D'Elios; Giuseppe Di Mauro; Mattia Doria; Luciana Indinnimeo; Andrea Lo Vecchio; Francesco Macrì; Roberto Mattina; Vito Leonardo Miniello; Michele Miraglia Del Giudice; Guido Morbin; Marco Antonio Motisi; Andrea Novelli; Anna Teresa Palamara; Maria Laura Panatta; Angela Pasinato; Diego Peroni; Katia Perruccio; Giorgio Piacentini; Massimo Pifferi; Lorenzo Pignataro; Emanuela Sitzia; Chiara Tersigni; Sara Torretta; Irene Trambusti; Giulia Trippella; Diletta Valentini; Sandro Valentini; Attilio Varricchio; Maria Carmen Verga; Claudio Vicini; Marco Zecca; Alberto Villani Journal: Ital J Pediatr Date: 2021-10-25 Impact factor: 2.638