| Literature DB >> 25818437 |
Shuhuan Li1, Shumei Zhai1, Yin Liu1, Hongyu Zhou1, Jinmei Wu1, Qing Jiao1, Bin Zhang1, Hao Zhu2, Bing Yan3.
Abstract
We demonstrate that nano-hydrophobicity, which governs the biological aggressiveness of nanoparticles, is determined by the outermost regions of surface ligands. We have also successfully modulated nano-hydrophobicity using systematic surface ligand modifications and built the first computational model of nano-hydrophobicity.Entities:
Keywords: Cytotoxicity; Gold; Hydrophilicity/hydrophobicity; Macrophages; Nanoparticle; Transmission electron microscopy (TEM)
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Year: 2015 PMID: 25818437 PMCID: PMC5586105 DOI: 10.1016/j.biomaterials.2015.02.043
Source DB: PubMed Journal: Biomaterials ISSN: 0142-9612 Impact factor: 12.479