Literature DB >> 25814400

Immune biomarkers: the promises and pitfalls of personalized medicine.

Joanna C D Willis1, Graham M Lord1.   

Abstract

Substantial progress in molecular immunology, coupled with an increasing focus on translational research and an enthusiasm for personalized medicine, has resulted in a rapid expansion in the field of immune biomarkers in recent years. In this Science and Society article, we provide a conceptual overview of the field and discuss the progress that has been made so far, as well as the future potential in the context of the scientific, logistical, financial, legal and ethical framework within which this research is being carried out and translated into clinical use.

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Year:  2015        PMID： 25814400     DOI： 10.1038/nri3820

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   53.106


  45 in total

Review 1.  Biomarkers and surrogate endpoints: preferred definitions and conceptual framework.

Authors: 
Journal:  Clin Pharmacol Ther       Date:  2001-03       Impact factor: 6.875

Review 2.  Systems immunology: a survey of modeling formalisms, applications and simulation tools.

Authors:  Vipin Narang; James Decraene; Shek-Yoon Wong; Bindu S Aiswarya; Andrew R Wasem; Shiang Rong Leong; Alexandre Gouaillard
Journal:  Immunol Res       Date:  2012-09       Impact factor: 2.829

Review 3.  Cell therapy as a strategy to minimize maintenance immunosuppression in solid organ transplant recipients.

Authors:  Edward K Geissler; James A Hutchinson
Journal:  Curr Opin Organ Transplant       Date:  2013-08       Impact factor: 2.640

Review 4.  The pits and pearls in translating operational tolerance biomarkers into clinical practice.

Authors:  Silke Roedder; Xiaoxiao Gao; Minnie M Sarwal
Journal:  Curr Opin Organ Transplant       Date:  2012-12       Impact factor: 2.640

5.  Infliximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group.

Authors:  R Maini; E W St Clair; F Breedveld; D Furst; J Kalden; M Weisman; J Smolen; P Emery; G Harriman; M Feldmann; P Lipsky
Journal:  Lancet       Date:  1999-12-04       Impact factor: 79.321

6.  Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR).

Authors:  Evan M Kroh; Rachael K Parkin; Patrick S Mitchell; Muneesh Tewari
Journal:  Methods       Date:  2010-02-08       Impact factor: 3.608

7.  Current concepts in the diagnosis and management of cytokine release syndrome.

Authors:  Daniel W Lee; Rebecca Gardner; David L Porter; Chrystal U Louis; Nabil Ahmed; Michael Jensen; Stephan A Grupp; Crystal L Mackall
Journal:  Blood       Date:  2014-05-29       Impact factor: 22.113

8.  Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.

Authors:  Lam C Tsoi; Sarah L Spain; Jo Knight; Eva Ellinghaus; Philip E Stuart; Francesca Capon; Jun Ding; Yanming Li; Trilokraj Tejasvi; Johann E Gudjonsson; Hyun M Kang; Michael H Allen; Ross McManus; Giuseppe Novelli; Lena Samuelsson; Joost Schalkwijk; Mona Ståhle; A David Burden; Catherine H Smith; Michael J Cork; Xavier Estivill; Anne M Bowcock; Gerald G Krueger; Wolfgang Weger; Jane Worthington; Rachid Tazi-Ahnini; Frank O Nestle; Adrian Hayday; Per Hoffmann; Juliane Winkelmann; Cisca Wijmenga; Cordelia Langford; Sarah Edkins; Robert Andrews; Hannah Blackburn; Amy Strange; Gavin Band; Richard D Pearson; Damjan Vukcevic; Chris C A Spencer; Panos Deloukas; Ulrich Mrowietz; Stefan Schreiber; Stephan Weidinger; Sulev Koks; Külli Kingo; Tonu Esko; Andres Metspalu; Henry W Lim; John J Voorhees; Michael Weichenthal; H Erich Wichmann; Vinod Chandran; Cheryl F Rosen; Proton Rahman; Dafna D Gladman; Christopher E M Griffiths; Andre Reis; Juha Kere; Rajan P Nair; Andre Franke; Jonathan N W N Barker; Goncalo R Abecasis; James T Elder; Richard C Trembath
Journal:  Nat Genet       Date:  2012-11-11       Impact factor: 38.330

9.  IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel.

Authors:  Vanda A Lennon; Thomas J Kryzer; Sean J Pittock; A S Verkman; Shannon R Hinson
Journal:  J Exp Med       Date:  2005-08-08       Impact factor: 14.307

10.  Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.

Authors:  Charlie G Buffie; Vanni Bucci; Richard R Stein; Peter T McKenney; Lilan Ling; Asia Gobourne; Daniel No; Hui Liu; Melissa Kinnebrew; Agnes Viale; Eric Littmann; Marcel R M van den Brink; Robert R Jenq; Ying Taur; Chris Sander; Justin R Cross; Nora C Toussaint; Joao B Xavier; Eric G Pamer
Journal:  Nature       Date:  2014-10-22       Impact factor: 49.962
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  36 in total

Review 1.  Moving Biomarkers toward Clinical Implementation in Kidney Transplantation.

Authors:  Madhav C Menon; Barbara Murphy; Peter S Heeger
Journal:  J Am Soc Nephrol       Date:  2017-01-06       Impact factor: 10.121

Review 2.  Proteomics for Allergy: from Proteins to the Patients.

Authors:  Emmanuel Nony; Maxime Le Mignon; Sébastien Brier; Armelle Martelet; Philippe Moingeon
Journal:  Curr Allergy Asthma Rep       Date:  2016-09       Impact factor: 4.806

Review 3.  Does evidence support the high expectations placed in precision medicine? A bibliographic review.

Authors:  Jordi Cortés; José Antonio González; María Nuncia Medina; Markus Vogler; Marta Vilaró; Matt Elmore; Stephen John Senn; Michael Campbell; Erik Cobo
Journal:  F1000Res       Date:  2018-01-09

4.  Influence of cytotoxic T lymphocyte antigen 4 genetic variants on acute rejection in kidney transplant patients: precision medicine perspective.

Authors:  Andia Taleb; Mahdi Afshari; Mohammad Samzadeh; Negar Sarhangi; Mohsen Nafar; Mandana Hasanzad
Journal:  J Diabetes Metab Disord       Date:  2021-12-02

5.  Orthogonal Comparison of Molecular Signatures of Kidney Transplants With Subclinical and Clinical Acute Rejection: Equivalent Performance Is Agnostic to Both Technology and Platform.

Authors:  S M Kurian; E Velazquez; R Thompson; T Whisenant; S Rose; N Riley; F Harrison; T Gelbart; J J Friedewald; J Charette; S Brietigam; J Peysakhovich; M R First; M M Abecassis; D R Salomon
Journal:  Am J Transplant       Date:  2017-04-03       Impact factor: 8.086

Review 6.  Protein function in precision medicine: deep understanding with machine learning.

Authors:  Burkhard Rost; Predrag Radivojac; Yana Bromberg
Journal:  FEBS Lett       Date:  2016-08-06       Impact factor: 4.124

Review 7.  The Use of Genomics and Pathway Analysis in Our Understanding and Prediction of Clinical Renal Transplant Injury.

Authors:  Madhav C Menon; Karen L Keung; Barbara Murphy; Philip J OʼConnell
Journal:  Transplantation       Date:  2016-07       Impact factor: 4.939

8.  A virtual host model of Mycobacterium tuberculosis infection identifies early immune events as predictive of infection outcomes.

Authors:  Louis R Joslyn; Jennifer J Linderman; Denise E Kirschner
Journal:  J Theor Biol       Date:  2022-01-31       Impact factor: 2.405

9.  A Combined microRNA and Chemokine Profile in Urine to Identify Rejection After Kidney Transplantation.

Authors:  Els M Gielis; Jacqueline D H Anholts; Els van Beelen; Geert W Haasnoot; Hans W De Fijter; Ingeborg Bajema; Sebastiaan Heidt; Mathijs van de Vrie; Luuk B Hilbrands; Marko J K Mallat; Kristien J Ledeganck; Frans H J Claas; Michael Eikmans
Journal:  Transplant Direct       Date:  2021-06-10

10.  Computational and Empirical Studies Predict Mycobacterium tuberculosis-Specific T Cells as a Biomarker for Infection Outcome.

Authors:  Simeone Marino; Hannah P Gideon; Chang Gong; Shawn Mankad; John T McCrone; Philana Ling Lin; Jennifer J Linderman; JoAnne L Flynn; Denise E Kirschner
Journal:  PLoS Comput Biol       Date:  2016-04-11       Impact factor: 4.475
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