Literature DB >> 25789869

Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies.

Jessica Nasica-Labouze1, Phuong H Nguyen1, Fabio Sterpone1, Olivia Berthoumieu2, Nicolae-Viorel Buchete, Sébastien Coté3, Alfonso De Simone4, Andrew J Doig5, Peter Faller2, Angel Garcia, Alessandro Laio6, Mai Suan Li7,8, Simone Melchionna9, Normand Mousseau, Yuguang Mu10, Anant Paravastu11, Samuela Pasquali1, David J Rosenman, Birgit Strodel12, Bogdan Tarus1, John H Viles13, Tong Zhang1,10, Chunyu Wang, Philippe Derreumaux1,14.   

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Year:  2015        PMID： 25789869      PMCID： PMC5504919          DOI： 10.1021/cr500638n

Source DB:  PubMed          Journal:  Chem Rev        ISSN： 0009-2665            Impact factor:   60.622


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  514 in total

1.  Mutations that replace aromatic side chains promote aggregation of the Alzheimer's Aβ peptide.

Authors:  Anne H Armstrong; Jermont Chen; Angela Fortner McKoy; Michael H Hecht
Journal:  Biochemistry       Date:  2011-04-22       Impact factor: 3.162

2.  Zinc ions promote Alzheimer Abeta aggregation via population shift of polymorphic states.

Authors:  Yifat Miller; Buyong Ma; Ruth Nussinov
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-06       Impact factor: 11.205

Review 3.  Diffraction to study protein and peptide assemblies.

Authors:  O Sumner Makin; Pawel Sikorski; Louise C Serpell
Journal:  Curr Opin Chem Biol       Date:  2006-08-23       Impact factor: 8.822

4.  Quasihomogeneous nucleation of amyloid beta yields numerical bounds for the critical radius, the surface tension, and the free energy barrier for nucleus formation.

Authors:  K Garai; B Sahoo; P Sengupta; S Maiti
Journal:  J Chem Phys       Date:  2008-01-28       Impact factor: 3.488

Review 5.  Coarse-grained models for protein folding and aggregation.

Authors:  Philippe Derreumaux
Journal:  Methods Mol Biol       Date:  2013

6.  Amyloid-β-induced synapse damage is mediated via cross-linkage of cellular prion proteins.

Authors:  Clive Bate; Alun Williams
Journal:  J Biol Chem       Date:  2011-09-07       Impact factor: 5.157

7.  Models of toxic beta-sheet channels of protegrin-1 suggest a common subunit organization motif shared with toxic alzheimer beta-amyloid ion channels.

Authors:  Hyunbum Jang; Buyong Ma; Ratnesh Lal; Ruth Nussinov
Journal:  Biophys J       Date:  2008-08-15       Impact factor: 4.033

8.  Amyloid plaques in PSAPP mice bind less metal than plaques in human Alzheimer's disease.

Authors:  Andreana C Leskovjan; Antonio Lanzirotti; Lisa M Miller
Journal:  Neuroimage       Date:  2009-05-28       Impact factor: 6.556

9.  Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin.

Authors:  Hans Zempel; Julia Luedtke; Yatender Kumar; Jacek Biernat; Hana Dawson; Eckhard Mandelkow; Eva-Maria Mandelkow
Journal:  EMBO J       Date:  2013-09-24       Impact factor: 11.598

10.  A multiscale approach to characterize the early aggregation steps of the amyloid-forming peptide GNNQQNY from the yeast prion sup-35.

Authors:  Jessica Nasica-Labouze; Massimiliano Meli; Philippe Derreumaux; Giorgio Colombo; Normand Mousseau
Journal:  PLoS Comput Biol       Date:  2011-05-19       Impact factor: 4.475
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  131 in total

1.  Steric Crowding of the Turn Region Alters the Tertiary Fold of Amyloid-β18-35 and Makes It Soluble.

Authors:  Muralidharan Chandrakesan; Debanjan Bhowmik; Bidyut Sarkar; Rajiv Abhyankar; Harwinder Singh; Mamata Kallianpur; Sucheta P Dandekar; Perunthiruthy K Madhu; Sudipta Maiti; Venus Singh Mithu
Journal:  J Biol Chem       Date:  2015-10-20       Impact factor: 5.157

2.  Stability of Aβ-fibril fragments in the presence of fatty acids.

Authors:  Wenhui Xi; Elliott K Vanderford; Qinxin Liao; Ulrich H E Hansmann
Journal:  Protein Sci       Date:  2019-09-11       Impact factor: 6.725

3.  The membrane axis of Alzheimer's nanomedicine.

Authors:  Yuhuan Li; Huayuan Tang; Nicholas Andrikopoulos; Ibrahim Javed; Luca Cecchetto; Aparna Nandakumar; Aleksandr Kakinen; Thomas P Davis; Feng Ding; Pu Chun Ke
Journal:  Adv Nanobiomed Res       Date:  2020-11-26

4.  Conformational Ensembles of the Wild-Type and S8C Aβ1-42 Dimers.

Authors:  Viet Hoang Man; Phuong H Nguyen; Philippe Derreumaux
Journal:  J Phys Chem B       Date:  2017-03-10       Impact factor: 2.991

5.  Exploring the aggregation free energy landscape of the amyloid-β protein (1-40).

Authors:  Weihua Zheng; Min-Yeh Tsai; Mingchen Chen; Peter G Wolynes
Journal:  Proc Natl Acad Sci U S A       Date:  2016-10-03       Impact factor: 11.205

Review 6.  Multiscale simulation of molecular processes in cellular environments.

Authors:  Mara Chiricotto; Fabio Sterpone; Philippe Derreumaux; Simone Melchionna
Journal:  Philos Trans A Math Phys Eng Sci       Date:  2016-11-13       Impact factor: 4.226

7.  Kinetics and mechanical stability of the fibril state control fibril formation time of polypeptide chains: A computational study.

Authors:  Maksim Kouza; Nguyen Truong Co; Mai Suan Li; Sebastian Kmiecik; Andrzej Kolinski; Andrzej Kloczkowski; Irina Alexandra Buhimschi
Journal:  J Chem Phys       Date:  2018-06-07       Impact factor: 3.488

8.  How accurate are your simulations? Effects of confined aqueous volume and AMBER FF99SB and CHARMM22/CMAP force field parameters on structural ensembles of intrinsically disordered proteins: Amyloid-β42 in water.

Authors:  Orkid Coskuner Weber; Vladimir N Uversky
Journal:  Intrinsically Disord Proteins       Date:  2017-10-30

9.  Conformational-Sensitive Fast Photochemical Oxidation of Proteins and Mass Spectrometry Characterize Amyloid Beta 1-42 Aggregation.

Authors:  Ke Sherry Li; Don L Rempel; Michael L Gross
Journal:  J Am Chem Soc       Date:  2016-09-12       Impact factor: 15.419

10.  Biocompatible and blood-brain barrier permeable carbon dots for inhibition of Aβ fibrillation and toxicity, and BACE1 activity.

Authors:  Xu Han; Zhifeng Jing; Wei Wu; Bing Zou; Zhili Peng; Pengyu Ren; Athula Wikramanayake; Zhongmin Lu; Roger M Leblanc
Journal:  Nanoscale       Date:  2017-09-14       Impact factor: 7.790
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