Mina Taghizadeh Asl1, Farzaneh Yousefi2, Reza Nemati2, Majid Assadi3. 1. Department of Nuclear Medicine, Kasra Hospital Tehran, Iran. 2. Department of Neurology, Bushehr Medical University Hospital, Bushehr University of Medical Sciences Bushehr, Iran. 3. The Persian Gulf Nuclear Medicine Research Center, Bushehr University of Medical Sciences Bushehr, Iran.
Abstract
OBJECTIVE: The present study was carried out to evaluate cerebral perfusion in different types of cerebral palsy (CP) patients. For those patients who underwent hyperbaric oxygen therapy, brain perfusion before and after the therapy was compared. METHODS: A total of 11 CP patients were enrolled in this study, of which 4 patients underwent oxygen therapy. Before oxygen therapy and at the end of 40 sessions of oxygen treatment, 99mTc-ECD brain perfusion single photon emission computed tomography (SPECT) was performed , and the results were compared. RESULTS: A total of 11 CP patients, 7 females and 4 males with an age range of 5-27 years participated in the study. In brain SPECT studies, all the patients showed perfusion impairments. The region most significantly involved was the frontal lobe (54.54%), followed by the temporal lobe (27.27%), the occipital lobe (18.18%), the visual cortex (18.18%), the basal ganglia (9.09%), the parietal lobe (9.09%), and the cerebellum (9.09%). Frontal-lobe hypoperfusion was seen in all types of cerebral palsy. Two out of 4 patients (2 males and 2 females) who underwent oxygen therapy revealed certain degree of brain perfusion improvement. CONCLUSION: This study demonstrated decreased cerebral perfusion in different types of CP patients. The study also showed that hyperbaric oxygen therapy improved cerebral perfusion in a few CP patients. However, it could keep the physiological discussion open and strenghten a link with other areas of neurology in which this approach may have some value.
OBJECTIVE: The present study was carried out to evaluate cerebral perfusion in different types of cerebral palsy (CP) patients. For those patients who underwent hyperbaric oxygen therapy, brain perfusion before and after the therapy was compared. METHODS: A total of 11 CPpatients were enrolled in this study, of which 4 patients underwent oxygen therapy. Before oxygen therapy and at the end of 40 sessions of oxygen treatment, 99mTc-ECD brain perfusion single photon emission computed tomography (SPECT) was performed , and the results were compared. RESULTS: A total of 11 CPpatients, 7 females and 4 males with an age range of 5-27 years participated in the study. In brain SPECT studies, all the patients showed perfusion impairments. The region most significantly involved was the frontal lobe (54.54%), followed by the temporal lobe (27.27%), the occipital lobe (18.18%), the visual cortex (18.18%), the basal ganglia (9.09%), the parietal lobe (9.09%), and the cerebellum (9.09%). Frontal-lobe hypoperfusion was seen in all types of cerebral palsy. Two out of 4 patients (2 males and 2 females) who underwent oxygen therapy revealed certain degree of brain perfusion improvement. CONCLUSION: This study demonstrated decreased cerebral perfusion in different types of CPpatients. The study also showed that hyperbaric oxygen therapy improved cerebral perfusion in a few CPpatients. However, it could keep the physiological discussion open and strenghten a link with other areas of neurology in which this approach may have some value.
Authors: J P Collet; M Vanasse; P Marois; M Amar; J Goldberg; J Lambert; M Lassonde; P Hardy; J Fortin; S D Tremblay; D Montgomery; J Lacroix; A Robinson; A Majnemer Journal: Lancet Date: 2001-02-24 Impact factor: 79.321
Authors: J C Baron; M Levasseur; B Mazoyer; F Legault-Demare; F Mauguière; S Pappata; P Jedynak; P Derome; J Cambier; S Tran-Dinh Journal: J Neurol Neurosurg Psychiatry Date: 1992-10 Impact factor: 10.154