Literature DB >> 25780355

Laser micro-grooved, Arginine-Glycine-Apspartic acid (RGD) coated dental implants, a 5 years radiographic follow-up.

Mohamed Ahmed Alkhodary1.   

Abstract

OBJECTIVES: This work has utilized laser direct writing to produce 10 microns wide uniform grooves on the surface of custom made titanium (Ti-6Al-4V) dental implants, and the tri-peptide RGD coating to produce a micromechanical and a chemical union with the tissues around the implant crest module and minimize crestal bone loss. The aim of this study was to follow these implants radiographically after five years of service under a mandibular overdenture.
METHODOLOGY: Standardized digital periapical radiographs and the computer software "Image J" were used to evaluate the bone density profile and vertical bone loss along the mesial and distal sides of the implants used in this study.
RESULTS: The results of this study demonstrated less vertical bone loss and higher bone density profiles next to the laser microgrooved implants coated with the RGD than those only having the laser micro-grooves.
CONCLUSION: The RGD coating has improved the bone density profile and reduced the vertical bone loss around the studied dental implants. However, further studies are needed to compare the effects of the laser micro-grooves versus other uniform or non uniform surface features; also, the RGD coating should be compared to other biomimetic surface coating materials.

Entities:  

Keywords:  RGD; dental implants; direct laser writing; laser micro-grooving; laser micromachining; titanium

Year:  2014        PMID: 25780355      PMCID: PMC4350890     

Source DB:  PubMed          Journal:  Int J Health Sci (Qassim)        ISSN: 1658-3639


  26 in total

1.  The effect of peptide surface density on mineralization of a matrix deposited by osteogenic cells.

Authors:  A Rezania; K E Healy
Journal:  J Biomed Mater Res       Date:  2000-12-15

2.  Effect of grooved titanium substratum on human osteoblastic cell growth.

Authors:  K Anselme; M Bigerelle; B Noël; A Iost; P Hardouin
Journal:  J Biomed Mater Res       Date:  2002-06-15

3.  Implant treatment in the edentulous mandible: a prospective study on Brånemark system implants over more than 20 years.

Authors:  Jan-Anders Ekelund; Lars W Lindquist; Gunnar E Carlsson; Torsten Jemt
Journal:  Int J Prosthodont       Date:  2003 Nov-Dec       Impact factor: 1.681

4.  In vivo study of the effect of RGD treatment on bone ongrowth on press-fit titanium alloy implants.

Authors:  Brian Elmengaard; Joan E Bechtold; Kjeld Søballe
Journal:  Biomaterials       Date:  2005-06       Impact factor: 12.479

5.  Influence of RGD-loaded titanium implants on bone formation in vivo.

Authors:  H C Kroese-Deutman; J van den Dolder; P H M Spauwen; J A Jansen
Journal:  Tissue Eng       Date:  2005 Nov-Dec

6.  Cell/surface interactions and adhesion on Ti-6Al-4V: effects of surface texture.

Authors:  J Chen; S Mwenifumbo; C Langhammer; J-P McGovern; M Li; A Beye; W O Soboyejo
Journal:  J Biomed Mater Res B Appl Biomater       Date:  2007-08       Impact factor: 3.368

Review 7.  Proteins and their peptide motifs in acellular apatite mineralization of scaffolds for tissue engineering.

Authors:  Johan Benesch; João F Mano; Rui L Reis
Journal:  Tissue Eng Part B Rev       Date:  2008-12       Impact factor: 6.389

8.  Design and function of novel osteoblast-adhesive peptides for chemical modification of biomaterials.

Authors:  K C Dee; T T Andersen; R Bizios
Journal:  J Biomed Mater Res       Date:  1998-06-05

9.  Crestal bone loss evaluation in osseotite expanded platform implants: a 5-year study.

Authors:  José Luis Calvo-Guirado; Gerardo Gómez-Moreno; Laura López-Marí; Javier Guardia; Bruno Negri; José María Martínez-González
Journal:  Clin Oral Implants Res       Date:  2011-03-21       Impact factor: 5.977

10.  Comparative in vivo study of commercially pure Ti implants with surfaces modified by laser with and without silicate deposition: biomechanical and scanning electron microscopy analysis.

Authors:  Francisley A Souza; Thallita P Queiroz; Antônio C Guastaldi; Idelmo R Garcia-Júnior; Osvaldo Magro-Filho; Renato S Nishioka; Karin E Sisti; Celso K Sonoda
Journal:  J Biomed Mater Res B Appl Biomater       Date:  2012-10-22       Impact factor: 3.368

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