Wenji Guo1, Kathryn E Bradbury2, Gillian K Reeves2, Timothy J Key2. 1. Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK. Electronic address: wenji.guo@ceu.ox.ac.uk. 2. Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Abstract
PURPOSE: Physical activity is thought to protect against obesity, but the evidence is limited and few large studies of this topic have direct, objective measures of several different anthropometric variables. We examined the association of self-reported physical activity with measures of total and central adiposity. METHODS: Our cross-sectional study included 38,201 premenopausal and 94,592 postmenopausal healthy women aged 40 to 70 years in UK Biobank, recruited from 2006 to 2010. RESULTS: Means for total and vigorous physical activity were 31.3 (SD, 30.8) and 9.7 (SD, 14.8) metabolic equivalent h/wk, respectively, for premenopausal and 34.4 (SD, 33.1) and 8.9 (SD, 15.6) metabolic equivalent h/wk, respectively, for postmenopausal women. Multiple linear regression models showed that in both premenopausal and postmenopausal women, body mass index, body fat mass and percentage, trunk fat mass and percentage, waist and hip circumference, and waist-to-hip ratio were lower in women with higher physical activity (P < .0001). Within each category of total physical activity, a larger proportion of vigorous physical activity was associated with lower adiposity (P < .0001). CONCLUSIONS: These findings support the roles of a physically active lifestyle and vigorous exercise in maintaining healthy body size and composition. Higher exercise intensity may be associated with lower adiposity, beyond the influence of exercise frequency and duration.
PURPOSE: Physical activity is thought to protect against obesity, but the evidence is limited and few large studies of this topic have direct, objective measures of several different anthropometric variables. We examined the association of self-reported physical activity with measures of total and central adiposity. METHODS: Our cross-sectional study included 38,201 premenopausal and 94,592 postmenopausal healthy women aged 40 to 70 years in UK Biobank, recruited from 2006 to 2010. RESULTS: Means for total and vigorous physical activity were 31.3 (SD, 30.8) and 9.7 (SD, 14.8) metabolic equivalent h/wk, respectively, for premenopausal and 34.4 (SD, 33.1) and 8.9 (SD, 15.6) metabolic equivalent h/wk, respectively, for postmenopausal women. Multiple linear regression models showed that in both premenopausal and postmenopausal women, body mass index, body fat mass and percentage, trunk fat mass and percentage, waist and hip circumference, and waist-to-hip ratio were lower in women with higher physical activity (P < .0001). Within each category of total physical activity, a larger proportion of vigorous physical activity was associated with lower adiposity (P < .0001). CONCLUSIONS: These findings support the roles of a physically active lifestyle and vigorous exercise in maintaining healthy body size and composition. Higher exercise intensity may be associated with lower adiposity, beyond the influence of exercise frequency and duration.
Authors: Jill Pell; Naveed Sattar; Jason M R Gill; Stuart R Gray; Carlos A Celis-Morales; Donald M Lyall; Fanny Petermann; Jana Anderson; Joey Ward; Stamatina Iliodromiti; Daniel F Mackay; Paul Welsh; Mark E S Bailey Journal: Int J Obes (Lond) Date: 2019-06-05 Impact factor: 5.095
Authors: Carlos A Celis-Morales; Paul Welsh; Donald M Lyall; Lewis Steell; Fanny Petermann; Jana Anderson; Stamatina Iliodromiti; Anne Sillars; Nicholas Graham; Daniel F Mackay; Jill P Pell; Jason M R Gill; Naveed Sattar; Stuart R Gray Journal: BMJ Date: 2018-05-08
Authors: Carlos A Celis-Morales; Donald M Lyall; Lewis Steell; Stuart R Gray; Stamatina Iliodromiti; Jana Anderson; Daniel F Mackay; Paul Welsh; Thomas Yates; Jill P Pell; Naveed Sattar; Jason M R Gill Journal: BMC Med Date: 2018-05-24 Impact factor: 8.775
Authors: Nicholas Graham; Joey Ward; Daniel Mackay; J P Pell; Jonathan Cavanagh; Sandosh Padmanabhan; Daniel J Smith Journal: BMJ Open Date: 2019-09-30 Impact factor: 2.692
Authors: Carlos A Celis-Morales; Donald M Lyall; Jana Anderson; Stamatina Iliodromiti; Yu Fan; Uduakobong E Ntuk; Daniel F Mackay; Jill P Pell; Naveed Sattar; Jason M R Gill Journal: Eur Heart J Date: 2017-01-07 Impact factor: 29.983