Literature DB >> 2572081

PQQ, the elusive coenzyme.

P M Gallop, M A Paz, R Flückiger, H M Kagan.   

Abstract

The recently discovered redox coenzyme, PQQ (methoxatin), is widely distributed. Quantitation of protein-bound PQQ has been difficult, but unique redox cycling reactions, which reflect its striking biological properties, reveal trace amounts. PQQ is a potential target for drugs.

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Year:  1989        PMID： 2572081     DOI： 10.1016/0968-0004(89)90169-2

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  6 in total

1.  Discovery of Hydroxylase Activity for PqqB Provides a Missing Link in the Pyrroloquinoline Quinone Biosynthetic Pathway.

Authors:  Eric M Koehn; John A Latham; Tara Armand; Robert L Evans; Xiongying Tu; Carrie M Wilmot; Anthony T Iavarone; Judith P Klinman
Journal:  J Am Chem Soc       Date:  2019-02-27       Impact factor: 15.419

2.  Cloning and characterization of a novel human homolog* of mouse U26, a putative PQQ-dependent AAS dehydrogenase.

Authors:  Liu Wang; Chaoneng Jil; Yiren Xu; Jian Xu; Jianfeng Dai; Qihan Wu; Maoqing Wu; Xianqiong Zou; Liyun Sun; Shaohua Gu; Yi Xie; Yumin Mao
Journal:  Mol Biol Rep       Date:  2005-03       Impact factor: 2.316

3.  The neuroprotective effect of pyrroloquinoline quinone on traumatic brain injury.

Authors:  Lili Zhang; Jie Liu; Chun Cheng; Ying Yuan; Biyun Yu; Aiguo Shen; Meijuan Yan
Journal:  J Neurotrauma       Date:  2011-12-20       Impact factor: 5.269

4.  Pyrroloquinoline quinone is a potent neuroprotective nutrient against 6-hydroxydopamine-induced neurotoxicity.

Authors:  Hirokazu Hara; Hideaki Hiramatsu; Tetsuo Adachi
Journal:  Neurochem Res       Date:  2007-03       Impact factor: 3.996

5.  Supplementation of PQQ from pregnancy prevents MK-801-induced schizophrenia-like behaviors in mice.

Authors:  Ying Peng; Dong Xu; Yuedi Ding; Xingqin Zhou
Journal:  Psychopharmacology (Berl)       Date:  2022-03-16       Impact factor: 4.530

6.  Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression.

Authors:  Winyoo Chowanadisai; Kathryn A Bauerly; Eskouhie Tchaparian; Alice Wong; Gino A Cortopassi; Robert B Rucker
Journal:  J Biol Chem       Date:  2009-10-27       Impact factor: 5.157
  6 in total

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