Literature DB >> 25686280

Coprisamides A and B, new branched cyclic peptides from a gut bacterium of the dung beetle Copris tripartitus.

Soohyun Um1, So Hyun Park, Jihye Kim, Hyen Joo Park, Keebeom Ko, Hea-Son Bang, Sang Kook Lee, Jongheon Shin, Dong-Chan Oh.   

Abstract

Coprisamides A and B (1 and 2) were isolated from a bacterium in the gut of the dung beetle Copris tripartitus. Spectroscopic analysis revealed that the planar structures of 1 and 2 are novel cyclic heptapeptides bearing unusual units, such as β-methylaspartic acid and 2,3-diaminopropanoic acid branched to valine and 2-heptatrienyl cinnamic acid. Absolute configurations were established by chemical derivatization and chiroptical spectroscopy. The coprisamides displayed significant activity for induction of quinone reductase.

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Year:  2015        PMID： 25686280     DOI： 10.1021/acs.orglett.5b00249

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  8 in total

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2.  Eighth Korea-Japan Chemical Biology symposium: chemical biology notes from a small island.

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Journal:  Antibiotics (Basel)       Date:  2018-09-13

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Authors:  Joon Soo An; Seong-Heon Hong; Elisabeth Somers; Jayho Lee; Byung-Yong Kim; Donghee Woo; Suk Won Kim; Hee-Jeon Hong; Shin-Il Jo; Jongheon Shin; Ki-Bong Oh; Dong-Chan Oh
Journal:  Front Microbiol       Date:  2020-10-30       Impact factor: 5.640

7.  Pentaminomycins C-E: Cyclic Pentapeptides as Autophagy Inducers from a Mealworm Beetle Gut Bacterium.

Authors:  Sunghoon Hwang; Ly Thi Huong Luu Le; Shin-Il Jo; Jongheon Shin; Min Jae Lee; Dong-Chan Oh
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Review 8.  An Overview of Antimicrobial Compounds from African Edible Insects and Their Associated Microbiota.

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  8 in total

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