Literature DB >> 25653445

Glycosylation of mouse DPP4 plays a role in inhibiting Middle East respiratory syndrome coronavirus infection.

Kayla M Peck1, Adam S Cockrell2, Boyd L Yount3, Trevor Scobey3, Ralph S Baric4, Mark T Heise5.   

Abstract

Middle East respiratory syndrome coronavirus (MERS-CoV) utilizes dipeptidyl peptidase 4 (DPP4) as an entry receptor. Mouse DPP4 (mDPP4) does not support MERS-CoV entry; however, changes at positions 288 and 330 can confer permissivity. Position 330 changes the charge and glycosylation state of mDPP4. We show that glycosylation is a major factor impacting DPP4 receptor function. These results provide insight into DPP4 species-specific differences impacting MERS-CoV host range and may inform MERS-CoV mouse model development.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2015        PMID： 25653445      PMCID： PMC4442375          DOI： 10.1128/JVI.03445-14

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  15 in total

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Authors:  D E Wentworth; K V Holmes
Journal:  J Virol       Date:  2001-10       Impact factor: 5.103

2.  Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus.

Authors:  V Stalin Raj; Saskia L Smits; Lisette B Provacia; Judith M A van den Brand; Lidewij Wiersma; Werner J D Ouwendijk; Theo M Bestebroer; Monique I Spronken; Geert van Amerongen; Peter J M Rottier; Ron A M Fouchier; Berend Jan Bosch; Albert D M E Osterhaus; Bart L Haagmans
Journal:  J Virol       Date:  2013-11-20       Impact factor: 5.103

3.  Receptor variation and susceptibility to Middle East respiratory syndrome coronavirus infection.

Authors:  Arlene Barlan; Jincun Zhao; Mayukh K Sarkar; Kun Li; Paul B McCray; Stanley Perlman; Tom Gallagher
Journal:  J Virol       Date:  2014-02-19       Impact factor: 5.103

4.  Mouse dipeptidyl peptidase 4 is not a functional receptor for Middle East respiratory syndrome coronavirus infection.

Authors:  Adam S Cockrell; Kayla M Peck; Boyd L Yount; Sudhakar S Agnihothram; Trevor Scobey; Nicole R Curnes; Ralph S Baric; Mark T Heise
Journal:  J Virol       Date:  2014-02-26       Impact factor: 5.103

5.  Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4.

Authors:  Neeltje van Doremalen; Kerri L Miazgowicz; Shauna Milne-Price; Trenton Bushmaker; Shelly Robertson; Dana Scott; Joerg Kinne; Jason S McLellan; Jiang Zhu; Vincent J Munster
Journal:  J Virol       Date:  2014-06-04       Impact factor: 5.103

6.  Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe.

Authors:  Augustina Annan; Heather J Baldwin; Victor Max Corman; Stefan M Klose; Michael Owusu; Evans Ewald Nkrumah; Ebenezer Kofi Badu; Priscilla Anti; Olivia Agbenyega; Benjamin Meyer; Samuel Oppong; Yaw Adu Sarkodie; Elisabeth K V Kalko; Peter H C Lina; Elena V Godlevska; Chantal Reusken; Antje Seebens; Florian Gloza-Rausch; Peter Vallo; Marco Tschapka; Christian Drosten; Jan Felix Drexler
Journal:  Emerg Infect Dis       Date:  2013-03       Impact factor: 6.883

7.  I-TASSER server for protein 3D structure prediction.

Authors:  Yang Zhang
Journal:  BMC Bioinformatics       Date:  2008-01-23       Impact factor: 3.169

8.  Middle East respiratory syndrome coronavirus in bats, Saudi Arabia.

Authors:  Ziad A Memish; Nischay Mishra; Kevin J Olival; Shamsudeen F Fagbo; Vishal Kapoor; Jonathan H Epstein; Rafat Alhakeem; Abdulkareem Durosinloun; Mushabab Al Asmari; Ariful Islam; Amit Kapoor; Thomas Briese; Peter Daszak; Abdullah A Al Rabeeah; W Ian Lipkin
Journal:  Emerg Infect Dis       Date:  2013-11       Impact factor: 6.883

9.  The Middle East respiratory syndrome coronavirus (MERS-CoV) does not replicate in Syrian hamsters.

Authors:  Emmie de Wit; Joseph Prescott; Laura Baseler; Trenton Bushmaker; Tina Thomas; Matthew G Lackemeyer; Cynthia Martellaro; Shauna Milne-Price; Elaine Haddock; Bart L Haagmans; Heinz Feldmann; Vincent J Munster
Journal:  PLoS One       Date:  2013-07-02       Impact factor: 3.240

10.  Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC.

Authors:  V Stalin Raj; Huihui Mou; Saskia L Smits; Dick H W Dekkers; Marcel A Müller; Ronald Dijkman; Doreen Muth; Jeroen A A Demmers; Ali Zaki; Ron A M Fouchier; Volker Thiel; Christian Drosten; Peter J M Rottier; Albert D M E Osterhaus; Berend Jan Bosch; Bart L Haagmans
Journal:  Nature       Date:  2013-03-14       Impact factor: 49.962
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  33 in total

1.  Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection.

Authors:  Kirsten A Kulcsar; Christopher M Coleman; Sarah E Beck; Matthew B Frieman
Journal:  JCI Insight       Date:  2019-10-17

Review 2.  The battle against SARS and MERS coronaviruses: Reservoirs and Animal Models.

Authors:  Shu-Ran Gong; Lin-Lin Bao
Journal:  Animal Model Exp Med       Date:  2018-07-28

3.  CD8+ T Cells and Macrophages Regulate Pathogenesis in a Mouse Model of Middle East Respiratory Syndrome.

Authors:  Christopher M Coleman; Jeanne M Sisk; Gabor Halasz; Jixin Zhong; Sarah E Beck; Krystal L Matthews; Thiagarajan Venkataraman; Sanjay Rajagopalan; Christos A Kyratsous; Matthew B Frieman
Journal:  J Virol       Date:  2016-12-16       Impact factor: 5.103

4.  Permissivity of Dipeptidyl Peptidase 4 Orthologs to Middle East Respiratory Syndrome Coronavirus Is Governed by Glycosylation and Other Complex Determinants.

Authors:  Kayla M Peck; Trevor Scobey; Jesica Swanstrom; Kara L Jensen; Christina L Burch; Ralph S Baric; Mark T Heise
Journal:  J Virol       Date:  2017-09-12       Impact factor: 5.103

5.  Exceptional diversity and selection pressure on coronavirus host receptors in bats compared to other mammals.

Authors:  Hannah K Frank; David Enard; Scott D Boyd
Journal:  Proc Biol Sci       Date:  2022-07-27       Impact factor: 5.530

Review 6.  Structure, Function, and Evolution of Coronavirus Spike Proteins.

Authors:  Fang Li
Journal:  Annu Rev Virol       Date:  2016-08-25       Impact factor: 10.431

7.  Mapping the Specific Amino Acid Residues That Make Hamster DPP4 Functional as a Receptor for Middle East Respiratory Syndrome Coronavirus.

Authors:  Neeltje van Doremalen; Kerri L Miazgowicz; Vincent J Munster
Journal:  J Virol       Date:  2016-05-12       Impact factor: 5.103

8.  The Role of Host Genetic Factors in Coronavirus Susceptibility: Review of Animal and Systematic Review of Human Literature.

Authors:  Marissa LoPresti; David B Beck; Priya Duggal; Derek A T Cummings; Benjamin D Solomon
Journal:  medRxiv       Date:  2020-06-03

Review 9.  Animal models of Middle East respiratory syndrome coronavirus infection.

Authors:  Neeltje van Doremalen; Vincent J Munster
Journal:  Antiviral Res       Date:  2015-07-17       Impact factor: 5.970

Review 10.  Humanized Mice for Infectious and Neurodegenerative disorders.

Authors:  Prasanta K Dash; Santhi Gorantla; Larisa Poluektova; Mahmudul Hasan; Emiko Waight; Chen Zhang; Milica Markovic; Benson Edagwa; Jatin Machhi; Katherine E Olson; Xinglong Wang; R Lee Mosley; Bhavesh Kevadiya; Howard E Gendelman
Journal:  Retrovirology       Date:  2021-06-05       Impact factor: 3.768
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