Literature DB >> 2564696

Multidrug resistance in cancer.

N Kartner1, V Ling.   

Abstract

Chemotherapy often fails because a tumor develops resistance to an array of different drugs. A single glycoprotein turns out to be responsible: it proliferates in some cells and pumps out the drugs. Now that the protein pump has been identified it may be possible to interfere with its action or to make it the target for drugs that destroy the cancer cell.

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Year:  1989        PMID： 2564696     DOI： 10.1038/scientificamerican0389-44

Source DB:  PubMed          Journal:  Sci Am        ISSN： 0036-8733            Impact factor:   2.142


  24 in total

Review 1.  Genetic aspects of multidrug resistance.

Authors:  M Pauly; F Ries; M Dicato
Journal:  Med Oncol Tumor Pharmacother       Date:  1992

2.  Adrenergic regulation of intercellular communications between cultured striatal astrocytes from the mouse.

Authors:  C Giaume; P Marin; J Cordier; J Glowinski; J Premont
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-01       Impact factor: 11.205

Review 3.  Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis.

Authors:  T Wallimann; M Wyss; D Brdiczka; K Nicolay; H M Eppenberger
Journal:  Biochem J       Date:  1992-01-01       Impact factor: 3.857

Review 4.  In vitro microfluidic models of tumor microenvironment to screen transport of drugs and nanoparticles.

Authors:  Altug Ozcelikkale; Hye-Ran Moon; Michael Linnes; Bumsoo Han
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2017-02-14

5.  Immunocytochemical detection of P-glycoprotein in the management of malignant effusions.

Authors:  P Athanassiadou; P Athanassiades; E Petrakakou; C Zerva; M Mavrikakis
Journal:  J Cancer Res Clin Oncol       Date:  1997       Impact factor: 4.553

Review 6.  Important issues in high dose chemotherapy and stem cell transplantation.

Authors:  R Gelfand; R Gandhi; S C Gulati
Journal:  Indian J Pediatr       Date:  1994 Sep-Oct       Impact factor: 1.967

7.  Influence of sequential exposure to R-verapamil or B8509-035 on rhodamine 123 accumulation in human lymphoblastoid cell lines.

Authors:  E Roller; B Klumpp; J Krause; M Eichelbaum; K Schumacher
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333

Review 8.  Multidrug resistance in cancer chemotherapy.

Authors:  N H Patel; M L Rothenberg
Journal:  Invest New Drugs       Date:  1994       Impact factor: 3.850

9.  Expression of multidrug resistance 1 (MDR1), multidrug resistance-related protein 1 (MRP1), lung resistance protein (LRP), and breast cancer resistance protein (BCRP) genes and clinical outcome in childhood acute lymphoblastic leukemia.

Authors:  M Kourti; N Vavatsi; N Gombakis; V Sidi; G Tzimagiorgis; T Papageorgiou; D Koliouskas; F Athanassiadou
Journal:  Int J Hematol       Date:  2007-08       Impact factor: 2.490

10.  MDR-1 gene expression, anthracycline retention and cytotoxicity in human lung-tumor cells from refractory patients.

Authors:  C Ramachandran; A Sauerteig; K S Sridhar; R J Thurer; A Krishan
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333
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