Literature DB >> 25645241

β-(1-Azulenyl)-L-alanine--a functional probe for determination of pKa of histidine residues.

Pallavi M Gosavi1, Yurii S Moroz, Ivan V Korendovych.   

Abstract

β-(1-Azulenyl)-L-alanine (AzAla) can be incorporated into the influenza A virus M2 proton channel. AzAla's sensitivity to the protonation state of the nearby histidines and the lack of environmental fluorescence dependence allow for direct and straightforward determination of histidine pKa values in ion channels.

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Year:  2015        PMID： 25645241     DOI： 10.1039/c4cc08720h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  10 in total

1.  Azulene-Derived Fluorescent Probe for Bioimaging: Detection of Reactive Oxygen and Nitrogen Species by Two-Photon Microscopy.

Authors:  Lloyd C Murfin; Maria Weber; Sang Jun Park; Won Tae Kim; Carlos M Lopez-Alled; Claire L McMullin; Fabienne Pradaux-Caggiano; Catherine L Lyall; Gabriele Kociok-Köhn; Jannis Wenk; Steven D Bull; Juyoung Yoon; Hwan Myung Kim; Tony D James; Simon E Lewis
Journal:  J Am Chem Soc       Date:  2019-11-27       Impact factor: 15.419

2.  Utility of 5-Cyanotryptophan Fluorescence as a Sensitive Probe of Protein Hydration.

Authors:  Beatrice N Markiewicz; Debopreeti Mukherjee; Thomas Troxler; Feng Gai
Journal:  J Phys Chem B       Date:  2016-01-28       Impact factor: 2.991

Review 3.  Minimalist IR and fluorescence probes of protein function.

Authors:  Pallavi M Gosavi; Ivan V Korendovych
Journal:  Curr Opin Chem Biol       Date:  2016-09-10       Impact factor: 8.822

4.  Direct Enzymatic Synthesis of a Deep-Blue Fluorescent Noncanonical Amino Acid from Azulene and Serine.

Authors:  Ella J Watkins; Patrick J Almhjell; Frances H Arnold
Journal:  Chembiochem       Date:  2019-11-18       Impact factor: 3.164

5.  Broad substrate tolerance of tubulin tyrosine ligase enables one-step site-specific enzymatic protein labeling.

Authors:  Dominik Schumacher; Oliver Lemke; Jonas Helma; Lena Gerszonowicz; Verena Waller; Tina Stoschek; Patrick M Durkin; Nediljko Budisa; Heinrich Leonhardt; Bettina G Keller; Christian P R Hackenberger
Journal:  Chem Sci       Date:  2017-03-20       Impact factor: 9.825

6.  Three-component reaction of azulene, aryl glyoxal and 1,3-dicarbonyl compound for the synthesis of various azulene derivatives.

Authors:  Jing Gong; Anatoly A Peshkov; Jiafeng Yu; Sagadat Amandykova; Aidana Gimnkhan; Jianjun Huang; Stepan Kashtanov; Olga P Pereshivko; Vsevolod A Peshkov
Journal:  RSC Adv       Date:  2020-03-10       Impact factor: 4.036

Review 7.  Tryptophan Synthase: Biocatalyst Extraordinaire.

Authors:  Ella Watkins-Dulaney; Sabine Straathof; Frances Arnold
Journal:  Chembiochem       Date:  2020-09-22       Impact factor: 3.164

8.  Azulenesulfonium Salts: Accessible, Stable, and Versatile Reagents for Cross-Coupling.

Authors:  Paul Cowper; Yu Jin; Michael D Turton; Gabriele Kociok-Köhn; Simon E Lewis
Journal:  Angew Chem Int Ed Engl       Date:  2016-01-14       Impact factor: 15.336

9.  Beneficial Impacts of Incorporating the Non-Natural Amino Acid Azulenyl-Alanine into the Trp-Rich Antimicrobial Peptide buCATHL4B.

Authors:  Areetha R D'Souza; Matthew R Necelis; Alona Kulesha; Gregory A Caputo; Olga V Makhlynets
Journal:  Biomolecules       Date:  2021-03-12

10.  Investigation of the Role of Aromatic Residues in the Antimicrobial Peptide BuCATHL4B.

Authors:  Matthew R Necelis; Luis E Santiago-Ortiz; Gregory A Caputo
Journal:  Protein Pept Lett       Date:  2021       Impact factor: 1.890
  10 in total

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