Literature DB >> 25643909

Therapeutic insights from genomic studies of head and neck squamous cell carcinomas.

Peter S Hammerman1, D Neil Hayes2, Jennifer R Grandis3.   

Abstract

Large and comprehensive genomic surveys of head and neck squamous cell carcinomas (HNSCC) are now greatly increasing our understanding of the diversity of this disease and the key genomic changes that drive these tumors. The results from these studies are beginning to inform the introduction of novel therapies for patients with HNSCCs. Here, we review some of the key findings from recent genomic studies of head and neck cancers, including the most comprehensive study to date from The Cancer Genome Atlas Network. ©2015 American Association for Cancer Research.

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Year:  2015        PMID： 25643909      PMCID： PMC4355279          DOI： 10.1158/2159-8290.CD-14-1205

Source DB:  PubMed          Journal:  Cancer Discov        ISSN： 2159-8274            Impact factor:   39.397


  32 in total

1.  Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas.

Authors:  Christine H Chung; Kim Ely; Loris McGavran; Marileila Varella-Garcia; Joel Parker; Natalie Parker; Carolyn Jarrett; Jesse Carter; Barbara A Murphy; James Netterville; Brian B Burkey; Robert Sinard; Anthony Cmelak; Shawn Levy; Wendell G Yarbrough; Robbert J C Slebos; Fred R Hirsch
Journal:  J Clin Oncol       Date:  2006-09-01       Impact factor: 44.544

Review 2.  Head and neck cancer.

Authors:  E E Vokes; R R Weichselbaum; S M Lippman; W K Hong
Journal:  N Engl J Med       Date:  1993-01-21       Impact factor: 91.245

Review 3.  Role of epidermal growth factor receptor pathway-targeted therapy in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck.

Authors:  Ezra E W Cohen
Journal:  J Clin Oncol       Date:  2006-06-10       Impact factor: 44.544

4.  Genome-wide DNA copy number alterations in head and neck squamous cell carcinomas with or without oncogene-expressing human papillomavirus.

Authors:  S J Smeets; B J M Braakhuis; S Abbas; P J F Snijders; B Ylstra; M A van de Wiel; G A Meijer; C R Leemans; R H Brakenhoff
Journal:  Oncogene       Date:  2006-04-20       Impact factor: 9.867

5.  TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.

Authors:  Patrick J Killela; Zachary J Reitman; Yuchen Jiao; Chetan Bettegowda; Nishant Agrawal; Luis A Diaz; Allan H Friedman; Henry Friedman; Gary L Gallia; Beppino C Giovanella; Arthur P Grollman; Tong-Chuan He; Yiping He; Ralph H Hruban; George I Jallo; Nils Mandahl; Alan K Meeker; Fredrik Mertens; George J Netto; B Ahmed Rasheed; Gregory J Riggins; Thomas A Rosenquist; Mark Schiffman; Ie-Ming Shih; Dan Theodorescu; Michael S Torbenson; Victor E Velculescu; Tian-Li Wang; Nicolas Wentzensen; Laura D Wood; Ming Zhang; Roger E McLendon; Darell D Bigner; Kenneth W Kinzler; Bert Vogelstein; Nickolas Papadopoulos; Hai Yan
Journal:  Proc Natl Acad Sci U S A       Date:  2013-03-25       Impact factor: 11.205

6.  Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression.

Authors:  Christine H Chung; Joel S Parker; Gamze Karaca; Junyuan Wu; William K Funkhouser; Dominic Moore; Dale Butterfoss; Dong Xiang; Adam Zanation; Xiaoying Yin; William W Shockley; Mark C Weissler; Lynn G Dressler; Carol G Shores; Wendell G Yarbrough; Charles M Perou
Journal:  Cancer Cell       Date:  2004-05       Impact factor: 31.743

7.  Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck.

Authors:  James A Bonner; Paul M Harari; Jordi Giralt; Nozar Azarnia; Dong M Shin; Roger B Cohen; Christopher U Jones; Ranjan Sur; David Raben; Jacek Jassem; Roger Ove; Merrill S Kies; Jose Baselga; Hagop Youssoufian; Nadia Amellal; Eric K Rowinsky; K Kian Ang
Journal:  N Engl J Med       Date:  2006-02-09       Impact factor: 91.245

8.  Head and neck carcinoma in the United States: first comprehensive report of the Longitudinal Oncology Registry of Head and Neck Carcinoma (LORHAN).

Authors:  K Kian Ang; Amy Chen; Walter J Curran; Adam S Garden; Paul M Harari; Barbara A Murphy; Stuart J Wong; Lisa A Bellm; Marc Schwartz; Jason Newman; Douglas Adkins; D Neil Hayes; Upendra Parvathaneni; David Brachman; Bassam Ghabach; Charles J Schneider; Michael Greenberg; Pramila R Anné
Journal:  Cancer       Date:  2012-05-08       Impact factor: 6.860

9.  Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes.

Authors:  Vonn Walter; Xiaoying Yin; Matthew D Wilkerson; Christopher R Cabanski; Ni Zhao; Ying Du; Mei Kim Ang; Michele C Hayward; Ashley H Salazar; Katherine A Hoadley; Karen Fritchie; Charles J Sailey; Charles G Sailey; Mark C Weissler; William W Shockley; Adam M Zanation; Trevor Hackman; Leigh B Thorne; William D Funkhouser; Kenneth L Muldrew; Andrew F Olshan; Scott H Randell; Fred A Wright; Carol G Shores; D Neil Hayes
Journal:  PLoS One       Date:  2013-02-22       Impact factor: 3.240

10.  Comprehensive genomic characterization of squamous cell lung cancers.

Authors: 
Journal:  Nature       Date:  2012-09-09       Impact factor: 49.962
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  43 in total

Review 1.  Therapeutic Implications of the Genetic Landscape of Head and Neck Cancer.

Authors:  Janice Cho; Daniel E Johnson; Jennifer R Grandis
Journal:  Semin Radiat Oncol       Date:  2018-01       Impact factor: 5.934

2.  Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas.

Authors:  Simon Papillon-Cavanagh; Chao Lu; Tenzin Gayden; Leonie G Mikael; Denise Bechet; Christina Karamboulas; Laurie Ailles; Jason Karamchandani; Dylan M Marchione; Benjamin A Garcia; Ilan Weinreb; David Goldstein; Peter W Lewis; Octavia Maria Dancu; Sandeep Dhaliwal; William Stecho; Christopher J Howlett; Joe S Mymryk; John W Barrett; Anthony C Nichols; C David Allis; Jacek Majewski; Nada Jabado
Journal:  Nat Genet       Date:  2017-01-09       Impact factor: 38.330

3.  The head and neck cancer immune landscape and its immunotherapeutic implications.

Authors:  Rajarsi Mandal; Yasin Şenbabaoğlu; Alexis Desrichard; Jonathan J Havel; Martin G Dalin; Nadeem Riaz; Ken-Wing Lee; Ian Ganly; A Ari Hakimi; Timothy A Chan; Luc Gt Morris
Journal:  JCI Insight       Date:  2016-10-20

4.  An Integrated Approach Identifies Mediators of Local Recurrence in Head and Neck Squamous Carcinoma.

Authors:  Francesca Citron; Joshua Armenia; Giovanni Franchin; Jerry Polesel; Renato Talamini; Sara D'Andrea; Sandro Sulfaro; Carlo M Croce; William Klement; David Otasek; Chiara Pastrello; Tomas Tokar; Igor Jurisica; Deborah French; Riccardo Bomben; Emanuela Vaccher; Diego Serraino; Barbara Belletti; Andrea Vecchione; Luigi Barzan; Gustavo Baldassarre
Journal:  Clin Cancer Res       Date:  2017-02-07       Impact factor: 12.531

5.  Identification and Clinical Validation of 4-lncRNA Signature for Predicting Survival in Head and Neck Squamous Cell Carcinoma.

Authors:  Yanping Ji; Yu Xue
Journal:  Onco Targets Ther       Date:  2020-08-21       Impact factor: 4.147

Review 6.  EGFR-targeted therapies in the post-genomic era.

Authors:  Mary Jue Xu; Daniel E Johnson; Jennifer R Grandis
Journal:  Cancer Metastasis Rev       Date:  2017-09       Impact factor: 9.264

7.  Evaluation of Prexasertib, a Checkpoint Kinase 1 Inhibitor, in a Phase Ib Study of Patients with Squamous Cell Carcinoma.

Authors:  David S Hong; Kathleen Moore; Manish Patel; Stefan C Grant; Howard A Burris; William N William; Suzanne Jones; Funda Meric-Bernstam; Jeffrey Infante; Lisa Golden; Wei Zhang; Ricardo Martinez; Sameera Wijayawardana; Richard Beckmann; Aimee Bence Lin; Cathy Eng; Johanna Bendell
Journal:  Clin Cancer Res       Date:  2018-04-11       Impact factor: 12.531

8.  Biomarker and Tumor Responses of Oral Cavity Squamous Cell Carcinoma to Trametinib: A Phase II Neoadjuvant Window-of-Opportunity Clinical Trial.

Authors:  Ravindra Uppaluri; Ashley E Winkler; Tianxiang Lin; Jonathan H Law; Bruce H Haughey; Brian Nussenbaum; Randal C Paniello; Jason T Rich; Jason A Diaz; Loren P Michel; Tanya Wildes; Gavin P Dunn; Paul Zolkind; Dorina Kallogjeri; Jay F Piccirillo; Farrokh Dehdashti; Barry A Siegel; Rebecca D Chernock; James S Lewis; Douglas R Adkins
Journal:  Clin Cancer Res       Date:  2016-11-09       Impact factor: 12.531

9.  miR-9 modulates and predicts the response to radiotherapy and EGFR inhibition in HNSCC.

Authors:  Francesca Citron; Ilenia Segatto; Lorena Musco; Ilenia Pellarin; Gian Luca Rampioni Vinciguerra; Giovanni Franchin; Giuseppe Fanetti; Francesco Miccichè; Vittorio Giacomarra; Valentina Lupato; Andrea Favero; Isabella Concina; Sanjana Srinivasan; Michele Avanzo; Isabella Castiglioni; Luigi Barzan; Sandro Sulfaro; Gianluigi Petrone; Andrea Viale; Giulio F Draetta; Andrea Vecchione; Barbara Belletti; Gustavo Baldassarre
Journal:  EMBO Mol Med       Date:  2021-06-01       Impact factor: 12.137

10.  Histopathological image and gene expression pattern analysis for predicting molecular features and prognosis of head and neck squamous cell carcinoma.

Authors:  Linyan Chen; Hao Zeng; Mingxuan Zhang; Yuling Luo; Xuelei Ma
Journal:  Cancer Med       Date:  2021-05-13       Impact factor: 4.452
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