Literature DB >> 25633006

Gut check: Clostridium difficile testing and treatment in the molecular testing era.

Whitney R Buckel1, Edina Avdic2, Karen C Carroll3, Vidhya Gunaseelan2, Eric Hadhazy3, Sara E Cosgrove3.   

Abstract

We evaluated the impact of nursing education and stewardship interventions on Clostridium difficile testing and treatment appropriateness. Diarrhea documentation increased for those with positive tests (45% to 70%); pretreatment laxative use decreased (50% to 19%). Appropriate treatment increased for severe infection (57% to 93%), but all asymptomatically colonized patients were treated.

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Year:  2015        PMID： 25633006     DOI： 10.1017/ice.2014.19

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN： 0899-823X            Impact factor:   3.254


  14 in total

1.  Clostridium difficile PCR Cycle Threshold Predicts Free Toxin.

Authors:  Fiona Senchyna; Rajiv L Gaur; Saurabh Gombar; Cynthia Y Truong; Lee F Schroeder; Niaz Banaei
Journal:  J Clin Microbiol       Date:  2017-06-14       Impact factor: 5.948

2.  Rising Stakes for Health Care-Associated Infection Prevention: Implications for the Clinical Microbiology Laboratory.

Authors:  Daniel J Diekema
Journal:  J Clin Microbiol       Date:  2017-01-25       Impact factor: 5.948

3.  Evaluation of Correlation between Pretest Probability for Clostridium difficile Infection and Clostridium difficile Enzyme Immunoassay Results.

Authors:  Jennie H Kwon; Kimberly A Reske; Tiffany Hink; C A Burnham; Erik R Dubberke
Journal:  J Clin Microbiol       Date:  2016-12-07       Impact factor: 5.948

Review 4.  Laboratory Tests for the Diagnosis of Clostridium difficile.

Authors:  Karen C Carroll; Masako Mizusawa
Journal:  Clin Colon Rectal Surg       Date:  2020-02-25

5.  The impact of an electronic medical record nudge on reducing testing for hospital-onset Clostridioides difficile infection.

Authors:  Jessica R Howard-Anderson; Mary Elizabeth Sexton; Chad Robichaux; Zanthia Wiley; Jay B Varkey; Sujit Suchindran; Benjamin Albrecht; K Ashley Jones; Scott K Fridkin; Jesse T Jacob
Journal:  Infect Control Hosp Epidemiol       Date:  2020-02-10       Impact factor: 3.254

6.  Real-Time Electronic Tracking of Diarrheal Episodes and Laxative Therapy Enables Verification of Clostridium difficile Clinical Testing Criteria and Reduction of Clostridium difficile Infection Rates.

Authors:  Cynthia Y Truong; Saurabh Gombar; Richard Wilson; Gopalakrishnan Sundararajan; Natasa Tekic; Marisa Holubar; John Shepard; Alexandra Madison; Lucy Tompkins; Neil Shah; Stan Deresinski; Lee F Schroeder; Niaz Banaei
Journal:  J Clin Microbiol       Date:  2017-03-01       Impact factor: 5.948

7.  Increased Clinical Specificity with Ultrasensitive Detection of Clostridioides difficile Toxins: Reduction of Overdiagnosis Compared to Nucleic Acid Amplification Tests.

Authors:  Johanna Sandlund; Joel Estis; Phoebe Katzenbach; Niamh Nolan; Kirstie Hinson; Jennifer Herres; Troy Pero; Gwyn Peterson; Jeung-Mi Schumaker; Craig Stevig; Rhonda Warren; Tsubasa West; Siu-Kei Chow
Journal:  J Clin Microbiol       Date:  2019-10-23       Impact factor: 5.948

Review 8.  Ultrasensitive Clostridioides difficile Toxin Testing for Higher Diagnostic Accuracy.

Authors:  Johanna Sandlund; Kerrie Davies; Mark H Wilcox
Journal:  J Clin Microbiol       Date:  2020-05-26       Impact factor: 5.948

9.  The Role of Diagnostic Stewardship in Clostridioides difficile Testing: Challenges and Opportunities.

Authors:  Frances J Boly; Kimberly A Reske; Jennie H Kwon
Journal:  Curr Infect Dis Rep       Date:  2020-02-17       Impact factor: 3.725

10.  Laxative Use Does Not Preclude Diagnosis or Reduce Disease Severity in Clostridiodes difficile Infection.

Authors:  Nicole C White; Rafael Mendo-Lopez; Konstantinos Papamichael; Christine A Cuddemi; Caitlin Barrett; Kaitlyn Daugherty; Nira Pollock; Ciaran P Kelly; Carolyn D Alonso
Journal:  Clin Infect Dis       Date:  2020-09-12       Impact factor: 9.079
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