Alejandra Parri1, David Benaiges2, Helmut Schröder3, Maria Izquierdo-Pulido4, José Ramón5, Montserrat Villatoro6, Juana Flores-Le Roux7, Alberto Goday7. 1. Department of Endocrinology and Nutrition, Parc de Salut Mar, Barcelona, Spain Cardiovascular Risk and Nutrition Research Group (CARIN-ULEC), IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain CIBER Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, Spain Research Program in Dietetics and Nutrition (EEES H0502), University of Barcelona, Spain Alejandra.parri.bonet@gmail.com aparri@parcdesalutmar.cat. 2. Department of Endocrinology and Nutrition, Parc de Salut Mar, Barcelona, Spain Cardiovascular Risk and Nutrition Research Group (CARIN-ULEC), IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain Department of Medicine, Universitat Autonoma de Barcelona, Spain. 3. Cardiovascular Risk and Nutrition Research Group (CARIN-ULEC), IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain CIBER Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Spain. 4. CIBER Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, Spain Department of Nutrition and Food Science, School of Pharmacy, University of Barcelona, Barcelona, Spain. 5. Unit of Gastrointestinal Surgery, Parc de Salut Mar, IMIM-Hospital del mar, Medical Research Institute, Barcelona, Spain. 6. Department of Endocrinology and Nutrition, Parc de Salut Mar, Barcelona, Spain Cardiovascular Risk and Nutrition Research Group (CARIN-ULEC), IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain CIBER Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, Spain. 7. Department of Endocrinology and Nutrition, Parc de Salut Mar, Barcelona, Spain Cardiovascular Risk and Nutrition Research Group (CARIN-ULEC), IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain CIBER Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, Spain Department of Medicine, Universitat Autonoma de Barcelona, Spain.
Abstract
BACKGROUND: This study evaluated the influence of patient characteristics, preoperative weight loss, and type of surgical procedure on long-term weight loss after bariatric surgery (BS). METHODS: Subjects were a prospective cohort of 95 patients who underwent BS with 4 years of follow-up. Seventy-seven patients (81.1%) underwent laparoscopic Roux-en-Y gastric bypass, and 18 (18.9%) had laparoscopic sleeve gastrectomy. Age, gender, initial body mass index (BMI), preoperative percentage of excess weight loss, presence of type 2 diabetes mellitus, current smoking status, and surgical technique were analyzed via multivariate linear regression analysis to identify predictors of weight loss during the 4 years after the surgery. RESULTS: Maximum percentage of excess weight loss was obtained at 18 months. Age and preoperative BMI were negatively associated with percentage of excess weight loss at 1, 2, 3, and 4 years after BS (P < .005). At 4 years, laparoscopic Roux-en-Y gastric bypass was independently associated with a higher weight loss than laparoscopic sleeve gastrectomy (P < .05). CONCLUSIONS: Younger age, lower BMI, and laparoscopic Roux-en-Y gastric bypass are independent predictors of long-term weight loss after BS.
BACKGROUND: This study evaluated the influence of patient characteristics, preoperative weight loss, and type of surgical procedure on long-term weight loss after bariatric surgery (BS). METHODS: Subjects were a prospective cohort of 95 patients who underwent BS with 4 years of follow-up. Seventy-seven patients (81.1%) underwent laparoscopic Roux-en-Y gastric bypass, and 18 (18.9%) had laparoscopic sleeve gastrectomy. Age, gender, initial body mass index (BMI), preoperative percentage of excess weight loss, presence of type 2 diabetes mellitus, current smoking status, and surgical technique were analyzed via multivariate linear regression analysis to identify predictors of weight loss during the 4 years after the surgery. RESULTS: Maximum percentage of excess weight loss was obtained at 18 months. Age and preoperative BMI were negatively associated with percentage of excess weight loss at 1, 2, 3, and 4 years after BS (P < .005). At 4 years, laparoscopic Roux-en-Y gastric bypass was independently associated with a higher weight loss than laparoscopic sleeve gastrectomy (P < .05). CONCLUSIONS: Younger age, lower BMI, and laparoscopic Roux-en-Y gastric bypass are independent predictors of long-term weight loss after BS.
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