Literature DB >> 30464862

An Initial Investigation of Unmanned Aircraft Systems (UAS) and Real-Time Organ Status Measurement for Transporting Human Organs.

Joseph R Scalea1, Stephen Restaino2, Matthew Scassero3, Gil Blankenship2, Stephen T Bartlett1,4, Norman Wereley5.   

Abstract

Organ transportation has yet to be substantially innovated. If organs could be moved by drone, instead of ill-timed commercial aircraft or expensive charter flights, lifesaving organs could be transplanted more quickly. A modified, six-rotor UAS was used to model situations relevant to organ transportation. To monitor the organ, we developed novel technologies that provided the real-time organ status using a wireless biosensor combined with an organ global positioning system. Fourteen drone organ missions were performed. Temperatures remained stable and low (2.5 °C). Pressure changes (0.37-0.86 kPa) correlated with increased altitude. Drone travel was associated with less vibration (<0.5 G) than was observed with fixed-wing flight (>2.0 G). Peak velocity was 67.6 km/h (42 m/h). Biopsies of the kidney taken prior to and after organ shipment revealed no damage resulting from drone travel. The longest flight was 3.0 miles, modeling an organ flight between two inner city hospitals. Organ transportation may be an ideal use-case for drones. With the development of faster, larger drones, long-distance drone organ shipment may result in substantially reduced cold ischemia times, subsequently improved organ quality, and thousands of lives saved.

Entities:  

Keywords:  Drone transportation; organ transplantation; transplant; transportation innovation; unmanned aircraft systems

Year:  2018        PMID: 30464862      PMCID: PMC6242697          DOI: 10.1109/JTEHM.2018.2875704

Source DB:  PubMed          Journal:  IEEE J Transl Eng Health Med        ISSN: 2168-2372            Impact factor:   3.316


  17 in total

1.  Kidney transplantation between seven pairs of identical twins.

Authors:  J E MURRAY; J P MERRILL; J H HARRISON
Journal:  Ann Surg       Date:  1958-09       Impact factor: 12.969

2.  Time to Delivery of an Automated External Defibrillator Using a Drone for Simulated Out-of-Hospital Cardiac Arrests vs Emergency Medical Services.

Authors:  Andreas Claesson; Anders Bäckman; Mattias Ringh; Leif Svensson; Per Nordberg; Therese Djärv; Jacob Hollenberg
Journal:  JAMA       Date:  2017-06-13       Impact factor: 56.272

3.  The Impact of Total Ischemic Time, Donor Age and the Pathway of Donor Death on Graft Outcomes After Deceased Donor Kidney Transplantation.

Authors:  Germaine Wong; Armando Teixeira-Pinto; Jeremy R Chapman; Jonathan C Craig; Henry Pleass; Stephen McDonald; Wai H Lim
Journal:  Transplantation       Date:  2017-06       Impact factor: 4.939

Review 4.  Drone delivery of medications: Review of the landscape and legal considerations.

Authors:  Connie A Lin; Karishma Shah; Lt Col Cherie Mauntel; Sachin A Shah
Journal:  Am J Health Syst Pharm       Date:  2017-12-13       Impact factor: 2.637

5.  Drone transportation of blood products.

Authors:  Timothy Amukele; Paul M Ness; Aaron A R Tobian; Joan Boyd; Jeff Street
Journal:  Transfusion       Date:  2016-11-11       Impact factor: 3.157

6.  The impact of proposed changes in liver allocation policy on cold ischemia times and organ transportation costs.

Authors:  D A DuBay; P A MacLennan; R D Reed; M Fouad; M Martin; C B Meeks; G Taylor; M L Kilgore; M Tankersley; S H Gray; J A White; D E Eckhoff; J E Locke
Journal:  Am J Transplant       Date:  2015-02       Impact factor: 8.086

7.  Organ transplantation in Switzerland: impact of the new transplant law on cold ischaemia time and organ transports.

Authors:  Nadine B Uehlinger; Franziska Beyeler; Julius Weiss; Hans-Peter Marti; Franz F Immer
Journal:  Swiss Med Wkly       Date:  2010-04-17       Impact factor: 2.193

8.  Impact of Operational Theater on Combat and Noncombat Trauma-Related Infections.

Authors:  David R Tribble; Ping Li; Tyler E Warkentien; Bradley A Lloyd; Elizabeth R Schnaubelt; Anuradha Ganesan; William Bradley; Deepak Aggarwal; M Leigh Carson; Amy C Weintrob; Clinton K Murray
Journal:  Mil Med       Date:  2016-10       Impact factor: 1.437

9.  Improving organ procurement practices in Michigan.

Authors:  R J Lynch; A K Mathur; J C Hundley; J Kubus; R E Pietroski; B J Mattice; J D Punch; M J Englesbe
Journal:  Am J Transplant       Date:  2009-07-28       Impact factor: 8.086

10.  Each additional hour of cold ischemia time significantly increases the risk of graft failure and mortality following renal transplantation.

Authors:  Agnes Debout; Yohann Foucher; Katy Trébern-Launay; Christophe Legendre; Henri Kreis; Georges Mourad; Valérie Garrigue; Emmanuel Morelon; Fanny Buron; Lionel Rostaing; Nassim Kamar; Michèle Kessler; Marc Ladrière; Alexandra Poignas; Amina Blidi; Jean-Paul Soulillou; Magali Giral; Etienne Dantan
Journal:  Kidney Int       Date:  2014-09-17       Impact factor: 10.612

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  6 in total

1.  Pathologic Blood Samples Tolerate Exposure to Vibration and High Turbulence in Simulated Drone Flights, but Plasma Samples Should be Centrifuged After Flight.

Authors:  Karl Arne Johannessen; Nina Kristin Steen Wear; Karin Toska; Morten Hansbo; Jens Petter Berg; Erik Fosse
Journal:  IEEE J Transl Eng Health Med       Date:  2021-01-20       Impact factor: 3.316

2.  A Drone Logistic Model for Transporting the Complete Analytic Volume of a Large-Scale University Laboratory.

Authors:  Karl-Arne Johannessen; Hans Comtet; Erik Fosse
Journal:  Int J Environ Res Public Health       Date:  2021-04-26       Impact factor: 3.390

3.  Modeling quarantine during epidemics and mass-testing using drones.

Authors:  Leonid Sedov; Alexander Krasnochub; Valentin Polishchuk
Journal:  PLoS One       Date:  2020-06-24       Impact factor: 3.240

4.  Realities of Using Drones to Transport Laboratory Samples: Insights from Attended Routes in a Mixed-Methods Study.

Authors:  Hans E Comtet; Martina Keitsch; Karl-Arne Johannessen
Journal:  J Multidiscip Healthc       Date:  2022-08-31

5.  Substance Use Disorders and COVID-19: Multi-Faceted Problems Which Require Multi-Pronged Solutions.

Authors:  Wossenseged Birhane Jemberie; Jennifer Stewart Williams; Malin Eriksson; Ann-Sofie Grönlund; Nawi Ng; Marcus Blom Nilsson; Mojgan Padyab; Kelsey Caroline Priest; Mikael Sandlund; Fredrik Snellman; Dennis McCarty; Lena M Lundgren
Journal:  Front Psychiatry       Date:  2020-07-21       Impact factor: 4.157

6.  The Moderating Role of Pro-Innovative Leadership and Gender as an Enabler for Future Drone Transports in Healthcare Systems.

Authors:  Hans E Comtet; Karl-Arne Johannessen
Journal:  Int J Environ Res Public Health       Date:  2021-03-05       Impact factor: 3.390

  6 in total

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