Literature DB >> 25585680

Preclinical data reproducibility for R&D--the challenge for neuroscience.

Thomas Steckler1.   

Abstract

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Year:  2015        PMID: 25585680     DOI: 10.1007/s00213-014-3836-3

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN: 0033-3158            Impact factor:   4.530


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  34 in total

1.  Therapeutic area influences drug development costs.

Authors:  Simon Frantz
Journal:  Nat Rev Drug Discov       Date:  2004-06       Impact factor: 84.694

2.  In search of preclinical robustness.

Authors:  Ian S Peers; Peter R Ceuppens; Chris Harbron
Journal:  Nat Rev Drug Discov       Date:  2012-10       Impact factor: 84.694

Review 3.  Power failure: why small sample size undermines the reliability of neuroscience.

Authors:  Katherine S Button; John P A Ioannidis; Claire Mokrysz; Brian A Nosek; Jonathan Flint; Emma S J Robinson; Marcus R Munafò
Journal:  Nat Rev Neurosci       Date:  2013-04-10       Impact factor: 34.870

4.  Irish university labs face external audits.

Authors:  Richard Van Noorden
Journal:  Nature       Date:  2014-06-19       Impact factor: 49.962

5.  Social science. Publication bias in the social sciences: unlocking the file drawer.

Authors:  Annie Franco; Neil Malhotra; Gabor Simonovits
Journal:  Science       Date:  2014-08-28       Impact factor: 47.728

6.  The costs and underappreciated consequences of research misconduct: a case study.

Authors:  Arthur M Michalek; Alan D Hutson; Camille P Wicher; Donald L Trump
Journal:  PLoS Med       Date:  2010-08-17       Impact factor: 11.069

7.  Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models".

Authors:  Nicholas F Fitz; Andrea A Cronican; Iliya Lefterov; Radosveta Koldamova
Journal:  Science       Date:  2013-05-24       Impact factor: 47.728

8.  Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models".

Authors:  Ina Tesseur; Adrian C Lo; Anouk Roberfroid; Sofie Dietvorst; Bianca Van Broeck; Marianne Borgers; Harrie Gijsen; Diederik Moechars; Marc Mercken; John Kemp; Rudi D'Hooge; Bart De Strooper
Journal:  Science       Date:  2013-05-24       Impact factor: 47.728

9.  Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models".

Authors:  Ashleigh R Price; Guilian Xu; Zoe B Siemienski; Lisa A Smithson; David R Borchelt; Todd E Golde; Kevin M Felsenstein
Journal:  Science       Date:  2013-05-24       Impact factor: 47.728

10.  P-values in genomics: apparent precision masks high uncertainty.

Authors:  L C Lazzeroni; Y Lu; I Belitskaya-Lévy
Journal:  Mol Psychiatry       Date:  2014-01-14       Impact factor: 15.992

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  9 in total

1.  Editorial: Reproducibility in Research: A Cautionary Tale and Lessons Not Learned.

Authors:  Agnes Schonbrunn
Journal:  Mol Endocrinol       Date:  2015-09

2.  Editorial: Reporting guidelines for psychopharmacology.

Authors:  Thomas Steckler; H Valerie Curran; Harriet de Wit; Oliver Howes; Daniel Hoyer; Irwin Lucki; Klaus A Miczek; A Leslie Morrow; Lawrence H Price; Trevor W Robbins
Journal:  Psychopharmacology (Berl)       Date:  2016-04       Impact factor: 4.530

Review 3.  The subchronic phencyclidine rat model: relevance for the assessment of novel therapeutics for cognitive impairment associated with schizophrenia.

Authors:  Sanna K Janhunen; Heta Svärd; John Talpos; Gaurav Kumar; Thomas Steckler; Niels Plath; Linda Lerdrup; Trine Ruby; Marie Haman; Roger Wyler; Theresa M Ballard
Journal:  Psychopharmacology (Berl)       Date:  2015-06-14       Impact factor: 4.530

4.  Acetaldehyde sequestration by D-penicillamine prevents ethanol relapse-like drinking in rats: evidence from an operant self-administration paradigm.

Authors:  Lucía Martí-Prats; Teodoro Zornoza; José Antonio López-Moreno; Luis Granero; Ana Polache
Journal:  Psychopharmacology (Berl)       Date:  2015-07-09       Impact factor: 4.530

Review 5.  Toward more predictive genetic mouse models of Alzheimer's disease.

Authors:  Kristen D Onos; Stacey J Sukoff Rizzo; Gareth R Howell; Michael Sasner
Journal:  Brain Res Bull       Date:  2015-12-17       Impact factor: 4.077

6.  Optimizing reproducibility of operant testing through reinforcer standardization: identification of key nutritional constituents determining reward strength in touchscreens.

Authors:  Eun Woo Kim; Benjamin U Phillips; Christopher J Heath; So Yeon Cho; Hyunjeong Kim; Jemeen Sreedharan; Ho-Taek Song; Jong Eun Lee; Timothy J Bussey; Chul Hoon Kim; Eosu Kim; Lisa M Saksida
Journal:  Mol Brain       Date:  2017-07-17       Impact factor: 4.041

Review 7.  Pre-Clinical Studies with D-Penicillamine as a Novel Pharmacological Strategy to Treat Alcoholism: Updated Evidences.

Authors:  Alejandro Orrico; Lucía Martí-Prats; María J Cano-Cebrián; Luis Granero; Ana Polache; Teodoro Zornoza
Journal:  Front Behav Neurosci       Date:  2017-03-07       Impact factor: 3.558

8.  Reliability of the chronic mild stress model of depression: A user survey.

Authors:  Paul Willner
Journal:  Neurobiol Stress       Date:  2016-08-22

9.  Assessment of Cognitive Impairment in a Mouse Model of High-Fat Diet-Induced Metabolic Stress with Touchscreen-Based Automated Battery System.

Authors:  Saeram Lee; Jong Youl Kim; Eosu Kim; KyoungYul Seo; Youn Jae Kang; Jae Young Kim; Chul-Hoon Kim; Ho Taek Song; Lisa M Saksida; Jong Eun Lee
Journal:  Exp Neurobiol       Date:  2018-08-30       Impact factor: 3.261

  9 in total

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