Literature DB >> 23023666

In search of preclinical robustness.

Ian S Peers1, Peter R Ceuppens, Chris Harbron.   

Abstract

Systematic engagement of statisticians in preclinical research could help address the weaknesses that are undermining the likelihood of subsequent success in drug discovery and development.

Mesh：

Year:  2012        PMID： 23023666     DOI： 10.1038/nrd3849

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


  3 in total

1.  Drug development: Raise standards for preclinical cancer research.

Authors:  C Glenn Begley; Lee M Ellis
Journal:  Nature       Date:  2012-03-28       Impact factor: 49.962

2.  Believe it or not: how much can we rely on published data on potential drug targets?

Authors:  Florian Prinz; Thomas Schlange; Khusru Asadullah
Journal:  Nat Rev Drug Discov       Date:  2011-08-31       Impact factor: 84.694

3.  Why most published research findings are false.

Authors:  John P A Ioannidis
Journal:  PLoS Med       Date:  2005-08-30       Impact factor: 11.613
  3 in total
  18 in total

1.  Preclinical data reproducibility for R&D--the challenge for neuroscience.

Authors:  Thomas Steckler
Journal:  Psychopharmacology (Berl)       Date:  2015-01-14       Impact factor: 4.530

Review 2.  Introducing Therioepistemology: the study of how knowledge is gained from animal research.

Authors:  Joseph P Garner; Brianna N Gaskill; Elin M Weber; Jamie Ahloy-Dallaire; Kathleen R Pritchett-Corning
Journal:  Lab Anim (NY)       Date:  2017-03-22       Impact factor: 12.625

Review 3.  Advances in exercise, fitness, and performance genomics in 2014.

Authors:  Ruth J F Loos; James M Hagberg; Louis Pérusse; Stephen M Roth; Mark A Sarzynski; Bernd Wolfarth; Tuomo Rankinen; Claude Bouchard
Journal:  Med Sci Sports Exerc       Date:  2015-06       Impact factor: 5.411

Review 4.  The significance of meaning: why do over 90% of behavioral neuroscience results fail to translate to humans, and what can we do to fix it?

Authors:  Joseph P Garner
Journal:  ILAR J       Date:  2014

5.  From viability to cell death: Claims with insufficient evidence in high-impact cell culture studies.

Authors:  Ali Burak Özkaya; Caner Geyik
Journal:  PLoS One       Date:  2022-02-22       Impact factor: 3.240

Review 6.  Guidelines for in vivo mouse models of myocardial infarction.

Authors:  Merry L Lindsey; Keith R Brunt; Jonathan A Kirk; Petra Kleinbongard; John W Calvert; Lisandra E de Castro Brás; Kristine Y DeLeon-Pennell; Dominic P Del Re; Nikolaos G Frangogiannis; Stefan Frantz; Richard J Gumina; Ganesh V Halade; Steven P Jones; Rebecca H Ritchie; Francis G Spinale; Edward B Thorp; Crystal M Ripplinger; Zamaneh Kassiri
Journal:  Am J Physiol Heart Circ Physiol       Date:  2021-10-08       Impact factor: 5.125

7.  Editorial: preclinical data reproducibility for R&D - the challenge for neuroscience.

Authors:  Thomas Steckler
Journal:  Springerplus       Date:  2015-01-13

8.  Assessments of Research Competencies for Clinical Investigators: A Systematic Review.

Authors:  Phillip A Ianni; Elias M Samuels; Brenda L Eakin; Thomas E Perorazio; Vicki L Ellingrod
Journal:  Eval Health Prof       Date:  2019-12-23       Impact factor: 2.651

9.  Improving basic and translational science by accounting for litter-to-litter variation in animal models.

Authors:  Stanley E Lazic; Laurent Essioux
Journal:  BMC Neurosci       Date:  2013-03-22       Impact factor: 3.288

10.  Helping to drive the robustness of preclinical research - the assay capability tool.

Authors:  Katrina Gore; Phil Stanley
Journal:  Pharmacol Res Perspect       Date:  2015-07-24
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.