Song Liu1, Hao Wang2, Wenxian Guan2, Liang Pan1, Zhuping Zhou1, Haiping Yu1, Tian Liu3, Xiaofeng Yang3, Jian He1, Zhengyang Zhou1. 1. Department of Radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China. 2. Department of Gastrointestinal Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China. 3. Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
Abstract
BACKGROUND: To determine if the apparent diffusion coefficient (ADC) values of gastric cancers on the preoperative diffusion weighted imaging (DWI) correlate with the postoperative TNMs of the lesions. METHODS: In a retrospective clinical study, seventy patients with gastric cancers were enrolled and each underwent a MRI before surgery. DWI was obtained with a single-shot, echo-planar imaging sequence in the axial plane (b values: 0 and 1000 s/mm(2) ). The mean and minimum ADC values of the gastric cancers were calculated and compared among various postoperative TNM staging. RESULTS: Both mean and minimum ADC values of the gastric cancers correlated with the postoperative T staging (r = -0.464, -0.476; both P < 0.001), N staging (r = -0.402, -0.397; P = 0.001, 0.002) and TNM staging (r = -0.446, -0.437; both P < 0.001). The areas under the receiver operating characteristic (ROC) curves for the differentiating lymph node metastasis were 0.788 for the mean ADC values (P = 0.001) and 0.778 for the minimum ADC values (P = 0.001). CONCLUSION: The preoperative ADC values of gastric cancers can help to assess the postoperative TNM staging.
BACKGROUND: To determine if the apparent diffusion coefficient (ADC) values of gastric cancers on the preoperative diffusion weighted imaging (DWI) correlate with the postoperative TNMs of the lesions. METHODS: In a retrospective clinical study, seventy patients with gastric cancers were enrolled and each underwent a MRI before surgery. DWI was obtained with a single-shot, echo-planar imaging sequence in the axial plane (b values: 0 and 1000 s/mm(2) ). The mean and minimum ADC values of the gastric cancers were calculated and compared among various postoperative TNM staging. RESULTS: Both mean and minimum ADC values of the gastric cancers correlated with the postoperative T staging (r = -0.464, -0.476; both P < 0.001), N staging (r = -0.402, -0.397; P = 0.001, 0.002) and TNM staging (r = -0.446, -0.437; both P < 0.001). The areas under the receiver operating characteristic (ROC) curves for the differentiating lymph node metastasis were 0.788 for the mean ADC values (P = 0.001) and 0.778 for the minimum ADC values (P = 0.001). CONCLUSION: The preoperative ADC values of gastric cancers can help to assess the postoperative TNM staging.
Authors: Alicia S Borggreve; Lucas Goense; Hylke J F Brenkman; Stella Mook; Gert J Meijer; Frank J Wessels; Marcel Verheij; Edwin P M Jansen; Richard van Hillegersberg; Peter S N van Rossum; Jelle P Ruurda Journal: Br J Radiol Date: 2019-03-05 Impact factor: 3.039