| Literature DB >> 25576985 |
Tiago Casella1, María Margarita Rodríguez2, Juliana Tiemi Takahashi3, Barbara Ghiglione2, Milena Dropa4, Ednei Assunção5, Maurício Lacerda Nogueira3, Nilton Lincopan6, Gabriel Gutkind2, Mara Corrêa Lelles Nogueira7.
Abstract
CTX-M-type extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae have been increasingly identified in humans and animals, and their potential transmission by contaminated food has been highlighted. In this study, we report for the first time the isolation of multidrug-resistant (MDR) Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis strains harboring blaCTXM-2 or blaCTXM-8 gene variants in chicken meat sold in markets in southeast Brazil. In this regard, the genetic environment of the blaCTX-M-2 gene is composed of a complex class 1 integron and an ISCR1-associated sequence with dfr and/or aadA gene cassettes located within the variable region. In summary, chicken meat may be a reservoir of MDR Enterobacteriaceae harboring blaCTX-M-type genes, which is a public health concern.Entities:
Keywords: CTX-M; Chicken meat; ISCR1; Poultry
Mesh：
Substances：
Year: 2014 PMID： 25576985 DOI： 10.1016/j.ijfoodmicro.2014.12.001
Source DB: PubMed Journal: Int J Food Microbiol ISSN： 0168-1605 Impact factor: 5.277