Literature DB >> 25574373

An evaluation of recruitment methods utilized for a clinical trial with periodontal and diabetes enrollment criteria: the Diabetes and Periodontal Therapy Trial.

Elinor R Schoenfeld1, Leslie Hyman1, Leslie Long Simpson2, Bryan Michalowicz3, Michael Reddy4, Marie Gelato5, Wei Hou1, Steven P Engebretson6, Catherine Hytner1, Pat Lenton7.   

Abstract

BACKGROUND: Diabetes and its complications are a major United States public health concern.
METHODS: The Diabetes and Periodontal Therapy Trial (DPTT) evaluated whether non-surgical treatment of periodontal disease influenced diabetes management among persons with Type 2 diabetes and periodontitis. The aim of this study was to evaluate DPTT's many recruitment strategies in terms of enrollment success. RESULTS/
CONCLUSION: Targeted recruitment strategies were more effective in identifying individuals who met periodontal and diabetes eligibility criteria. Individuals eligible for a baseline visit/enrollment were more often male, had a younger age at diabetes diagnosis, a longer diabetes duration, more often Hispanic and less often African-American. Tracking and evaluating recruitment sources during study enrollment optimized recruitment methods to enroll a diverse participant population based upon gender, race and ethnicity.

Entities:  

Keywords:  Type 2; clinical trial; diabetes; diabetes mellitus; periodontal disease; periodontitis; recruitment

Year:  2014        PMID: 25574373      PMCID: PMC4283836          DOI: 10.4155/cli.14.99

Source DB:  PubMed          Journal:  Clin Investig (Lond)        ISSN: 2041-6792


  23 in total

1.  Response to direct and indirect recruitment for a randomised dental clinical trial in a multicultural population of elders.

Authors:  Michael I MacEntee; Christopher Wyatt; H Asuman Kiyak; Philippe P Hujoel; Rigmor E Persson; G Rutger Persson; L Virginia Powell
Journal:  Community Dent Oral Epidemiol       Date:  2002-10       Impact factor: 3.383

2.  Recruitment of participants to a multiple sclerosis trial: the CombiRx experience.

Authors:  Minal J Bhanushali; Tarah Gustafson; Steve Powell; Robin A Conwit; Jerry S Wolinsky; Gary R Cutter; Fred D Lublin; Stacey S Cofield
Journal:  Clin Trials       Date:  2014-04       Impact factor: 2.486

3.  Subject recruitment, retention, and compliance in clinical trials in periodontics.

Authors:  P M Milgrom; P P Hujoel; P Weinstein; D W Holborow
Journal:  Ann Periodontol       Date:  1997-03

4.  Prevalence of periodontitis in adults in the United States: 2009 and 2010.

Authors:  P I Eke; B A Dye; L Wei; G O Thornton-Evans; R J Genco
Journal:  J Dent Res       Date:  2012-08-30       Impact factor: 6.116

5.  Periodontal disease and NIDDM in Pima Indians.

Authors:  R G Nelson; M Shlossman; L M Budding; D J Pettitt; M F Saad; R J Genco; W C Knowler
Journal:  Diabetes Care       Date:  1990-08       Impact factor: 19.112

6.  Does periodontal care improve glycemic control? The Department of Veterans Affairs Dental Diabetes Study.

Authors:  Judith A Jones; Donald R Miller; Carolyn J Wehler; Sharron E Rich; Elizabeth A Krall-Kaye; Linda C McCoy; Cindy L Christiansen; James A Rothendler; Raul I Garcia
Journal:  J Clin Periodontol       Date:  2006-11-24       Impact factor: 8.728

7.  Periodontal status of diabetics compared with nondiabetics: a meta-analysis.

Authors:  Yousef S Khader; Ali S Dauod; Saleh S El-Qaderi; Ahmed Alkafajei; Walid Q Batayha
Journal:  J Diabetes Complications       Date:  2006 Jan-Feb       Impact factor: 2.852

8.  Dialogues on diversifying clinical trials: successful strategies for engaging women and minorities in clinical trials.

Authors:  Meghan Coakley; Emmanuel Olutayo Fadiran; L Jo Parrish; Rachel A Griffith; Eleanor Weiss; Christine Carter
Journal:  J Womens Health (Larchmt)       Date:  2012-07       Impact factor: 2.681

9.  Recruitment strategies in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial.

Authors:  Connie Kingry; Arnaud Bastien; Gillian Booth; Therese S Geraci; Brenda R Kirpach; Laura C Lovato; Karen L Margolis; Yves Rosenberg; JoAnne M Sperl-Hillen; Laura Vargo; Jeff D Williamson; Jeffrey L Probstfield
Journal:  Am J Cardiol       Date:  2007-04-12       Impact factor: 2.778

10.  Design features of the Diabetes and Periodontal Therapy Trial (DPTT): a multicenter randomized single-masked clinical trial testing the effect of nonsurgical periodontal therapy on glycosylated hemoglobin (HbA1c) levels in subjects with type 2 diabetes and chronic periodontitis.

Authors:  S Engebretson; M Gelato; L Hyman; B S Michalowicz; E Schoenfeld
Journal:  Contemp Clin Trials       Date:  2013-09-27       Impact factor: 2.226

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