Darragh Halpenny1, Carole A Ridge2, Sara Hayes1, Junting Zheng3, Chaya S Moskowitz3, Andreas Rimner4, Michelle S Ginsberg5. 1. Department of Radiology, Memorial Sloan-Kettering Cancer Center (MSKCC), New York. 2. Department of Radiology, Mater Misericordiae University Hospital, Dublin, Ireland. 3. Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York. 4. Department of Thoracic Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York. 5. Department of Radiology, Memorial Sloan-Kettering Cancer Center (MSKCC), New York. Electronic address: ginsberm@MSKCC.ORG.
Abstract
INTRODUCTION: The objective of this study is to identify computed tomography (CT) features of local recurrence (LR) after stereotactic body radiation therapy (SBRT) for lung cancer. METHODS: Two hundred eighteen patients underwent SBRT for lung cancer from January 1st, 2006 to March 1st, 2011. Signs of LR recorded: opacity with new bulging margin, opacification of air bronchograms, enlarging pleural effusion, new or enlarging mass, and increased lung density at the treatment site. RESULTS: A new bulging margin at the treatment site was the only feature significantly associated with LR (P<.005). CONCLUSION: Most CT features classically associated with LR following conventional radiation therapy are unreliable for predicting LR following SBRT.
INTRODUCTION: The objective of this study is to identify computed tomography (CT) features of local recurrence (LR) after stereotactic body radiation therapy (SBRT) for lung cancer. METHODS: Two hundred eighteen patients underwent SBRT for lung cancer from January 1st, 2006 to March 1st, 2011. Signs of LR recorded: opacity with new bulging margin, opacification of air bronchograms, enlarging pleural effusion, new or enlarging mass, and increased lung density at the treatment site. RESULTS: A new bulging margin at the treatment site was the only feature significantly associated with LR (P<.005). CONCLUSION: Most CT features classically associated with LR following conventional radiation therapy are unreliable for predicting LR following SBRT.
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