| Literature DB >> 25565201 |
Maria Chiara Maiuri1, Guido Kroemer2.
Abstract
Cancers are often affected by derangements in mitochondrial (mt) function, as well as mtDNA mutations. In this issue, Tan et al. (2015) demonstrate that only mtDNA-depleted cancer cells capable of recovering mtDNA from the host form metastasizing cancers in vivo, revealing an essential requirement for oxidative phosphorylation in tumor progression.Entities:
Mesh：
Year: 2015 PMID： 25565201 DOI： 10.1016/j.cmet.2014.12.013
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287