Literature DB >> 25559791

Working with asbestos and the possible health risks.

D Sen1.   

Abstract

BACKGROUND: The generic term asbestos refers to a group of crystalline mineral silicates that occur naturally in various forms. Because of their properties of strength, heat and electrical resistance and their ability to withstand corrosion by acids and sea water, asbestos was used extensively both in the UK and worldwide. AIMS: To provide a historical perspective of this ubiquitous occupational hazard, consider the key changes in UK legislation aimed at improving the management of this occupational health risk and describe the evidence from the scientific literature concerning asbestos and disease.
METHODS: Original articles, reviews (including reference textbooks) and scientific literature in PubMed and other principal medical science databases, 1960-2014, were searched. Publications by regulatory agencies and by governmental organizations were also considered and included where relevant.
RESULTS: Asbestos remains the biggest cause of cancer deaths worldwide. For malignant mesothelioma deaths alone, it is estimated that in the UK, between 2015 and 2020, the number of cases will peak at 2500 cases annually. It is not clear whether there is a safe level of asbestos fibres in air. Evidence for the efficacy of health surveillance is lacking.
CONCLUSIONS: Although the use of asbestos was banned in the UK in 1985 (amosite and crocidolite) and 1999 (chrysotile), it remains a significant occupational risk factor for work-related morbidity and mortality, causing both benign and malignant diseases, often with long latency. Further research is needed regarding exposure levels and health surveillance. © Crown copyright 2015.

Entities:  

Keywords:  Asbestos; asbestosis; long latency; lung cancer; mesothelioma; screening.

Mesh:

Substances:

Year:  2015        PMID: 25559791     DOI: 10.1093/occmed/kqu175

Source DB:  PubMed          Journal:  Occup Med (Lond)        ISSN: 0962-7480            Impact factor:   1.611


  9 in total

1.  Pleural and peritoneal mesotheliomas in the Friuli Venezia Giulia register: data analysis from 1995 to 2015 in Northeastern Italy.

Authors:  Flavia D'Agostin; Paola De Michieli; Carolin Chermaz; Corrado Negro
Journal:  J Thorac Dis       Date:  2017-04       Impact factor: 2.895

2.  Exosomes from asbestos-exposed cells modulate gene expression in mesothelial cells.

Authors:  Phillip Munson; Ying-Wai Lam; Julie Dragon; Maximilian MacPherson; Arti Shukla
Journal:  FASEB J       Date:  2018-03-19       Impact factor: 5.191

3.  Current and future risks of asbestos exposure in the Australian community.

Authors:  Corie Gray; Renee N Carey; Alison Reid
Journal:  Int J Occup Environ Health       Date:  2016-09-09

Review 4.  Diagnostic value of microRNAs in asbestos exposure and malignant mesothelioma: systematic review and qualitative meta-analysis.

Authors:  Luigina Micolucci; Most Mauluda Akhtar; Fabiola Olivieri; Maria Rita Rippo; Antonio Domenico Procopio
Journal:  Oncotarget       Date:  2016-09-06

5.  Clustering of malignant pleural mesothelioma in asbestos factories: a subgroup analysis in a 29-year follow-up study to identify high-risk industries in Taiwan.

Authors:  Lukas Jyuhn-Hsiarn Lee; Cheng-Kuan Lin; Chih-Hong Pan; Yawen Cheng; Yu-Yin Chang; Saou-Hsing Liou; Jung-Der Wang
Journal:  BMJ Open       Date:  2018-12-09       Impact factor: 2.692

6.  The influence of genetic variability of DNA repair mechanisms on the risk of malignant mesothelioma.

Authors:  Kristina Levpuscek; Katja Goricar; Viljem Kovac; Vita Dolzan; Alenka Franko
Journal:  Radiol Oncol       Date:  2019-03-14       Impact factor: 2.991

7.  Using a Mobile Phone App to Identify and Assess Remaining Stocks of In Situ Asbestos in Australian Residential Settings.

Authors:  Matthew Govorko; Lin Fritschi; Alison Reid
Journal:  Int J Environ Res Public Health       Date:  2019-12-05       Impact factor: 3.390

Review 8.  Molecular Alterations in Malignant Pleural Mesothelioma: A Hope for Effective Treatment by Targeting YAP.

Authors:  Gérard Zalcman; Guénaëlle Levallet; Fatéméh Dubois; Céline Bazille; Jérôme Levallet; Elodie Maille; Solenn Brosseau; Jeannick Madelaine; Emmanuel Bergot
Journal:  Target Oncol       Date:  2022-07-30       Impact factor: 4.864

9.  Asbestosis is prevalent in a variety of construction industry trades.

Authors:  G I Walters; A S Robertson; P S Bhomra; P S Burge
Journal:  NPJ Prim Care Respir Med       Date:  2018-04-03       Impact factor: 2.871

  9 in total

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